{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T02:58:08Z","timestamp":1778122688949,"version":"3.51.4"},"reference-count":24,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2016,3,1]],"date-time":"2016-03-01T00:00:00Z","timestamp":1456790400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Am J Rhinol\ufffdAllergy"],"published-print":{"date-parts":[[2016,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Allergic rhinitis is a type 1 hypersensitivity reaction of the nasal mucosa, the primary mediator of which is immunoglobulin E. Allergic rhinitis occurs in children and adolescents.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study examined the relationship between allergies and the eosinophil-to-lymphocyte ratio in children with allergic rhinitis with a positive skin-prick test.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>This study was planned and performed as a case-control study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>There were 695 patients who presented to our clinic who were enrolled in the study. Only group 4 fit the criteria for allergic rhinitis. Group 1 (nonsensitized asymptomatic [control group]), group 2 (nonsensitized symptomatic), group 3 (sensitized asymptomatic), and group 4 (sensitized symptomatic). The patients\u2019 allergy symptoms and skin test results were assessed and compared. The eosinophil-to-lymphocyte ratio for each patient was calculated. The eosinophil and lymphocyte counts and the eosinophil-to-lymphocyte ratio were calculated for each group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The eosinophil-to-lymphocyte ratio and eosinophil counts in groups 3 and 4 were significantly higher (p &lt; 0.001 and p &lt; 0.001, respectively) than those in groups 1 and 2. The lymphocyte counts in groups 3 and 4 were significantly lower (p = 0.046) than those of groups 1 and 2.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The eosinophil-to-lymphocyte ratio may be used in conjunction with skin-prick testing in pediatric patients with allergic rhinitis. This parameter is inexpensive to measure and easy to use and calculate.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2500\/ajra.2016.30.4296","type":"journal-article","created":{"date-parts":[[2016,3,14]],"date-time":"2016-03-14T23:54:51Z","timestamp":1457999691000},"page":"e21-e25","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":31,"title":["Evaluation of the Eosinophil-to-lymphocyte Ratio in Pediatric Patients with Allergic Rhinitis"],"prefix":"10.1177","volume":"30","author":[{"given":"Alper","family":"Yenigun","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology, Faculty of Medicine, Bezmialem Vakif University, Fatih, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seda","family":"Sezen","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Faculty of Medicine, Bezmialem Vakif University, Fatih, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omer Faruk","family":"Calim","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Faculty of Medicine, Bezmialem Vakif University, Fatih, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Orhan","family":"Ozturan","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Faculty of Medicine, Bezmialem Vakif University, Fatih, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,3,1]]},"reference":[{"key":"bibr1-ajra.2016.30.4296","doi-asserted-by":"publisher","DOI":"10.2500\/108854100778249088"},{"key":"bibr2-ajra.2016.30.4296","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3038.2009.00933.x"},{"key":"bibr3-ajra.2016.30.4296","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)69283-0"},{"key":"bibr4-ajra.2016.30.4296","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2001.118891"},{"key":"bibr5-ajra.2016.30.4296","doi-asserted-by":"publisher","DOI":"10.1016\/S1081-1206(10)62550-1"},{"key":"bibr6-ajra.2016.30.4296","doi-asserted-by":"publisher","DOI":"10.1586\/ehm.11.81"},{"key":"bibr7-ajra.2016.30.4296","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2007.02.010"},{"key":"bibr8-ajra.2016.30.4296","doi-asserted-by":"publisher","DOI":"10.4065\/mcp.2009.0503"},{"key":"bibr9-ajra.2016.30.4296","doi-asserted-by":"publisher","DOI":"10.1016\/S1081-1206(10)62550-1"},{"key":"bibr10-ajra.2016.30.4296","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2008.05.006"},{"key":"bibr11-ajra.2016.30.4296","doi-asserted-by":"publisher","DOI":"10.3109\/00016480903311880"},{"key":"bibr12-ajra.2016.30.4296","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2009.12.989"},{"key":"bibr13-ajra.2016.30.4296","doi-asserted-by":"publisher","DOI":"10.2500\/ar.2014.5.0078"},{"key":"bibr14-ajra.2016.30.4296","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.2012.04048.x"},{"key":"bibr15-ajra.2016.30.4296","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.1994.tb00803.x"},{"key":"bibr16-ajra.2016.30.4296","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.1993.tb00742.x"},{"key":"bibr17-ajra.2016.30.4296","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(98)70329-X"},{"key":"bibr18-ajra.2016.30.4296","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2012.06.010"},{"key":"bibr19-ajra.2016.30.4296","first-page":"188","volume":"22","author":"Emin O.","year":"2012","journal-title":"J Investig Allergol Clin Immunol"},{"key":"bibr20-ajra.2016.30.4296","first-page":"494","volume":"26","author":"Luo H.","year":"2012","journal-title":"Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi"},{"key":"bibr21-ajra.2016.30.4296","doi-asserted-by":"publisher","DOI":"10.1097\/00063198-200301000-00008"},{"key":"bibr22-ajra.2016.30.4296","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2000.110156"},{"key":"bibr23-ajra.2016.30.4296","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2257.1997.00204.x"},{"key":"bibr24-ajra.2016.30.4296","doi-asserted-by":"publisher","DOI":"10.3109\/00365513.2013.769625"}],"container-title":["American Journal of Rhinology &amp; 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