{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:55:19Z","timestamp":1787025319715,"version":"build-2736575974"},"reference-count":18,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Am J Rhinol\ufffdAllergy"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The nasoseptal flap (NSF) is a universally used surgical technique to cover defects of the skull base after extended sinonasal surgery. Long-term follow-up of complications, sequelae, and smell function is largely unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The main objective of this study was to investigate monorhinal olfaction after transsphenoidal skull base surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients who underwent skull base surgery for midline lesions (craniopharyngioma and pituitary tumors) by using a NSF, also referred to as the Haddad flap, were assessed for their long-term outcome. Endoscopic examination was conducted and the bilateral \u201cSniffin\u2019 Sticks\u201d test was performed before surgery. Each side was tested separately in the postoperative follow-up consultation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twenty patients were included in the study. No flap failures were observed. One anterior perforation and one small posterior septal perforation were found during long-term follow-up. None of the patients had nasal breathing impairment, whereas two patients had nose bleeds. A significant decrease in olfactory function was observed on the flap donor side in four patients (20%) compared with that observed in one patient (5%) on the opposite side.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>NSF reconstructions for midline lesions were efficient and safe in the long term. Olfactory impairment on the donor side was frequently encountered. Although subclinical, these findings justified a monorhinal smell testing before surgery, which possibly prevented bilateral smell impairment in patient with preexisting single-sided olfactory loss.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.2500\/ajra.2017.31.4463","type":"journal-article","created":{"date-parts":[[2017,8,31]],"date-time":"2017-08-31T23:51:28Z","timestamp":1504223488000},"page":"334-337","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":43,"title":["Long-Term Olfactory Outcome after Nasoseptal Flap Reconstructions in Midline Skull Base Surgery"],"prefix":"10.1177","volume":"31","author":[{"given":"Michael B.","family":"Soyka","sequence":"first","affiliation":[{"name":"Department Otorhinolaryngology, Head and Neck Surgery, University and University Hospital Zurich, Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Serra","sequence":"additional","affiliation":[{"name":"Department Neurosurgery, University and University Hospital Zurich, Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Regli","sequence":"additional","affiliation":[{"name":"Department Neurosurgery, University and University Hospital Zurich, Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Meier","sequence":"additional","affiliation":[{"name":"Department Otorhinolaryngology, Head and Neck Surgery, University and University Hospital Zurich, Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Holzmann","sequence":"additional","affiliation":[{"name":"Department Otorhinolaryngology, Head and Neck Surgery, University and University Hospital Zurich, Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2017,9,1]]},"reference":[{"key":"bibr1-ajra.2017.31.4463","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1952.00710020018001"},{"key":"bibr2-ajra.2017.31.4463","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000234933.37779.e4"},{"key":"bibr3-ajra.2017.31.4463","doi-asserted-by":"publisher","DOI":"10.1097\/MOO.0000000000000115"},{"key":"bibr4-ajra.2017.31.4463","doi-asserted-by":"publisher","DOI":"10.1177\/0194599814561431"},{"key":"bibr5-ajra.2017.31.4463","doi-asserted-by":"publisher","DOI":"10.1177\/0194599815571284"},{"key":"bibr6-ajra.2017.31.4463","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24863"},{"key":"bibr7-ajra.2017.31.4463","doi-asserted-by":"publisher","DOI":"10.1177\/000348940111001015"},{"key":"bibr8-ajra.2017.31.4463","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24107"},{"key":"bibr9-ajra.2017.31.4463","first-page":"156","volume":"48","author":"Welge-Lussen A.","year":"2010","journal-title":"Rhinology"},{"key":"bibr10-ajra.2017.31.4463","doi-asserted-by":"publisher","DOI":"10.1055\/s-0035-1554905"},{"key":"bibr11-ajra.2017.31.4463","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2014.28.4109"},{"key":"bibr12-ajra.2017.31.4463","doi-asserted-by":"publisher","DOI":"10.1002\/lary.21890"},{"key":"bibr13-ajra.2017.31.4463","doi-asserted-by":"publisher","DOI":"10.1002\/alr.21069"},{"key":"bibr14-ajra.2017.31.4463","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2015.29.4206"},{"key":"bibr15-ajra.2017.31.4463","doi-asserted-by":"publisher","DOI":"10.1017\/S002221511500047X"},{"key":"bibr16-ajra.2017.31.4463","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-015-3729-z"},{"key":"bibr17-ajra.2017.31.4463","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2015.29.4165"},{"key":"bibr18-ajra.2017.31.4463","doi-asserted-by":"publisher","DOI":"10.3171\/2014.7.FOCUS14350"}],"container-title":["American Journal of Rhinology &amp; 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