{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T16:27:16Z","timestamp":1790958436572,"version":"4.1.0"},"reference-count":15,"publisher":"Oceanside Publications Inc.","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Food Allergy"],"published-print":{"date-parts":[[2020,9,1]]},"abstract":"<jats:p>Genetic modification of foods is one of the many ways of processing that can enhance foods to increase desirable qualities, such as herbicide tolerance, bacteria and insect resistance, improved nutritional value, and delayed ripening. However, a theoretical potential to increase the\n allergenicity of food proteins has been the subject of concern from critics. To prevent adverse effects from genetically modified (GM) crops, national and international organizations tightly regulate their production and recommend rigorous safety testing. Some safety tests were developed to\n assess potential allergenicity by studying the product\u2019s similarity to known allergenic proteins, its resistance to pepsin digestion, and its binding to immunoglobulin E (IgE) from sera of patients with known relevant allergies. To date, these safety assessments have only identified\n rare GM foods with the potential to lead to immunologic reactions. These foods were stopped from being marketed commercially, and the products on the market now have passed required safety assessments. The rise in the prevalence of food allergy preceded the commercialization of GM foods and\n has also occurred in countries with limited access to GM crops, which highlights a lack of causative association between the two. Several studies provided further reassurance with no evidence of higher potency in specific IgE binding to GM foods. There are no studies that demonstrate adverse\n reactions due to GM food consumption, and GM foods may have the beneficial potential to silence major allergenic proteins. Therefore, physicians and other health-care professionals should counsel patients that the scientific data do not support an increased risk of allergic responses to GM\n foods.<\/jats:p>","DOI":"10.2500\/jfa.2020.2.200012","type":"journal-article","created":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T04:40:03Z","timestamp":1598935203000},"page":"111-114","source":"Crossref","is-referenced-by-count":12,"title":["Genetically modified foods and food allergy"],"prefix":"10.2500","volume":"2","author":[{"given":"Stefani","family":"Su","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Idil Daloglu","family":"Ezhuthachan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Punita","family":"Ponda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1355","reference":[{"key":"B1","first-page":"508","article-title":"Effect of the food matrix and processing on the allergenic activity of foods","volume-title":"In:","author":"Mills","year":"2014"},{"key":"B2","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.anai.2017.07.010","article-title":"The allergenicity of genetically modified foods from genetically engineered crops: a narrative and systematic review","volume":"119","author":"Dunn","year":"2017","journal-title":"Ann Allergy Asthma Immunol"},{"key":"B3","doi-asserted-by":"crossref","first-page":"S20","DOI":"10.1016\/j.fct.2008.07.021","article-title":"Current codex guidelines for assessment of potential protein allergenicity","volume":"46","author":"Ladics","year":"2008","journal-title":"Food Chem Toxicol"},{"key":"B4","first-page":"291","article-title":"Genetically modified foods and allergy","volume":"23","author":"Lee","year":"2017","journal-title":"Hong Kong Med J"},{"key":"B5","first-page":"22984","article-title":"Statement of policy\u2014foods derived from new plant variations","volume":"57","year":"1992","journal-title":"Fed Regist"},{"key":"B6","first-page":"4862","article-title":"Guidance on allergenicity assessment of genetically modified plants","volume":"15","author":"Naegeli","year":"2017","journal-title":"EFSA J"},{"key":"B7","doi-asserted-by":"crossref","first-page":"1700278","DOI":"10.1002\/mnfr.201700278","article-title":"Current (food) allergenic risk assessment: is it fit for novel foods? 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