{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T06:51:14Z","timestamp":1792047074537,"version":"4.4.0"},"reference-count":0,"publisher":"Universidad del Valle","issue":"3","license":[{"start":{"date-parts":[[2021,6,29]],"date-time":"2021-06-29T00:00:00Z","timestamp":1624924800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":["colombiamedica.univalle.edu.co"],"crossmark-restriction":true},"short-container-title":["Colomb Med"],"abstract":"<jats:p>La gastrosquisis es un defecto estructural cong\u00e9nito de la pared abdominal, localizado con mayor frecuencia a la derecha del ombligo, a trav\u00e9s del cual sobresalen las v\u00edsceras abdominales. Durante mucho tiempo, sus aspectos evolutivos, etiol\u00f3gicos y epidemiol\u00f3gicos han sido un tema candente de controversia, aunque hallazgos recientes sugieren la participaci\u00f3n de alteraciones gen\u00e9ticas, cromos\u00f3micas, y la existencia de una v\u00eda patog\u00e9nica inductora de estr\u00e9s, en la que factores de riesgo como los demogr\u00e1ficos y ambientales pueden converger.\r\nCon el objetivo de ampliar la frontera del conocimiento sobre una malformaci\u00f3n que ha mostrado una creciente prevalencia global, hemos efectuado una revisi\u00f3n que incluye informaci\u00f3n, \u00a0del desarrollo embrionario de la pared corporal ventral, el intestino primitivo, \u00a0el complejo anillo-cord\u00f3n umbilical, y de las teor\u00edas acerca de su origen, patog\u00e9nesis e informaci\u00f3n epidemiol\u00f3gica reciente.<\/jats:p>","DOI":"10.25100\/cm.v52i3.4227","type":"journal-article","created":{"date-parts":[[2021,11,22]],"date-time":"2021-11-22T16:28:57Z","timestamp":1637598537000},"page":"e4004227","update-policy":"https:\/\/doi.org\/10.25100\/cm.crossmarkpolicy","source":"Crossref","is-referenced-by-count":14,"title":["Nuevas pistas para comprender la gastrosquisis. Embriolog\u00eda, patog\u00e9nesis y epidemiolog\u00eda"],"prefix":"10.25100","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0156-2577","authenticated-orcid":false,"given":"Lilian","family":"Chuaire-Noack","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10728","published-online":{"date-parts":[[2021,6,29]]},"container-title":["Colombia Medica"],"original-title":[],"link":[{"URL":"https:\/\/colombiamedica.univalle.edu.co\/index.php\/comedica\/article\/download\/4227\/6022","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/colombiamedica.univalle.edu.co\/index.php\/comedica\/article\/download\/4227\/6020","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/colombiamedica.univalle.edu.co\/index.php\/comedica\/article\/download\/4227\/6021","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/colombiamedica.univalle.edu.co\/index.php\/comedica\/article\/download\/4227\/6020","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,6]],"date-time":"2024-08-06T17:59:01Z","timestamp":1722967141000},"score":1,"resource":{"primary":{"URL":"https:\/\/colombiamedica.univalle.edu.co\/index.php\/comedica\/article\/view\/4227"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,29]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2021,6,29]]}},"URL":"https:\/\/doi.org\/10.25100\/cm.v52i3.4227","relation":{},"ISSN":["1657-9534","0120-8322"],"issn-type":[{"value":"1657-9534","type":"electronic"},{"value":"0120-8322","type":"print"}],"subject":[],"published":{"date-parts":[[2021,6,29]]},"assertion":[{"value":"Yes","name":"crosschecked","label":"CrossChecked"},{"value":"Yes","name":"peer_reviewed","label":"Peer Reviewed"}]}}