{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T02:50:26Z","timestamp":1777949426913,"version":"3.51.4"},"reference-count":25,"publisher":"Universidad del Valle","issue":"3","license":[{"start":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T00:00:00Z","timestamp":1759190400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},{"start":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T00:00:00Z","timestamp":1759190400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":["colombiamedica.univalle.edu.co"],"crossmark-restriction":true},"short-container-title":["Colomb Med"],"abstract":"<jats:p>Descripci\u00f3n del caso:Se presenta el primer caso humano en un entorno urbano de infecci\u00f3n por Rickettsia parkeri, cepa Atlantic Rainforest, en un paciente masculino de 8 a\u00f1os .\nHallazgos cl\u00ednicos:El paciente, quien refiri\u00f3 una picadura de garrapata, present\u00f3 fiebre (38 \u00b0C), mialgia, dolor abdominal, artralgia y linfadenopat\u00eda leve en la axila derecha. Se observ\u00f3 una lesi\u00f3n en el sitio de la picadura de la garrapata.\nTratamiento y resultados:Se obtuvo una muestra de biopsia del \u00e1rea de la picadura para diagn\u00f3stico mediante PCR y secuenciaci\u00f3n del fragmento de ADN, que mostr\u00f3 una homolog\u00eda del 100 % con Rickettsia parkeri, cepa Atlantic Rainforest, reportada en casos humanos en Brasil. El tratamiento consisti\u00f3 en 100 mg de doxiciclina durante 10 d\u00edas, con desaparici\u00f3n de los s\u00edntomas a las 24 horas de iniciado el tratamiento.\nRelevancia cl\u00ednica:Reportamos el primer caso de rickettsiosis por Rickettsia parkeri en un \u00e1rea urbana de M\u00e9xico. La infecci\u00f3n se considera de curso leve a moderado, aunque es inusual en ambientes urbanos. Los m\u00e9dicos deben estar atentos a las manifestaciones cl\u00ednicas asociadas a las picaduras de garrapata, especialmente cuando se presenta linfadenopat\u00eda.<\/jats:p>","DOI":"10.25100\/cm.v56i3.5779","type":"journal-article","created":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T16:44:44Z","timestamp":1763657084000},"page":"e5005779","update-policy":"https:\/\/doi.org\/10.25100\/cm.crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Primer caso urbano de rickettsiosis por Rickettsia parkeri (cepa Atlantic Rainforest) en M\u00e9rida, M\u00e9xico","First Urban Case of Rickettsia parkeri (Atlantic Rainforest Strain) Rickettsiosis in M\u00e9rida, Mexico"],"prefix":"10.25100","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5202-937X","authenticated-orcid":false,"given":"Gaspar Fernando","family":"Peniche-Lara","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3729-3797","authenticated-orcid":false,"given":"Karla","family":"Dzul-Rosado","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10728","published-online":{"date-parts":[[2025,9,30]]},"reference":[{"key":"99173","doi-asserted-by":"crossref","unstructured":"Labruna MB, Salim Mattar V, Nava S, et al. Rickettsioses in Latin America, Caribbean, Spain and Portugal. Rev MVZ Cordoba [Internet]. 2011 [cited 2022 Feb 7];16:2435-2457. Available from: https:\/\/revistamvz.unicordoba.edu.co\/article\/view\/282. https:\/\/doi.org\/10.21897\/rmvz.282","DOI":"10.21897\/rmvz.282"},{"key":"99174","doi-asserted-by":"crossref","unstructured":"Moo-Llanes DA, de Oca-Aguilar ACM, Romero-Salas D, et al. Inferring the Potential Distribution of an Emerging Rickettsiosis in America: The Case of Rickettsia parkeri. Pathogens [Internet]. 2021 [cited 2022 Feb 7];10. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/34068132\/. https:\/\/doi.org\/10.3390\/pathogens10050592 PMid:34068132 PMCid:PMC8152739","DOI":"10.3390\/pathogens10050592"},{"key":"99175","doi-asserted-by":"crossref","unstructured":"Paddock CD, Sumner JW, Comer JA, et al. Rickettsia parkeri: a newly recognized cause of spotted fever rickettsiosis in the United States. Clin Infect Dis [Internet]. 2004 [cited 2022 Feb 7];38:805-811. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/14999622\/. https:\/\/doi.org\/10.1086\/381894","DOI":"10.1086\/381894"},{"key":"99176","unstructured":"PMid:14999622"},{"key":"99177","doi-asserted-by":"crossref","unstructured":"Silva-Ramos CR, Hidalgo M, Faccini-Mart\u00ednez \u00c1A. Clinical, epidemiological, and laboratory features of Rickettsia parkeri rickettsiosis: A systematic review. Ticks Tick Borne Dis. 2021;12:101734. https:\/\/doi.org\/10.1016\/j.ttbdis.2021.101734 PMid:33989945","DOI":"10.1016\/j.ttbdis.2021.101734"},{"key":"99178","doi-asserted-by":"crossref","unstructured":"Barbieri ARM, Filho JM, Nieri-Bastos FA, et al. Epidemiology of Rickettsia sp. strain Atlantic rainforest in a spotted fever-endemic area of southern Brazil. Ticks Tick Borne Dis. 2014;5:848-853. https:\/\/doi.org\/10.1016\/j.ttbdis.2014.07.010 PMid:25108786","DOI":"10.1016\/j.ttbdis.2014.07.010"},{"key":"99179","doi-asserted-by":"crossref","unstructured":"Nieri-Bastos FA, Horta MC, Barros-Battesti DM, et al. Isolation of the Pathogen Rickettsia sp. Strain Atlantic Rainforest from Its Presumed Tick Vector, Amblyomma ovale (Acari: Ixodidae), from Two Areas of Brazil. J Med Entomol. 2016;53:977-981. https:\/\/doi.org\/10.1093\/jme\/tjw062 PMid:27146681","DOI":"10.1093\/jme\/tjw062"},{"key":"99180","doi-asserted-by":"crossref","unstructured":"Paddock CD, Allerdice MEJ, Karpathy SE, et al. Unique strain of Rickettsia parkeri associated with the hard tick Dermacentor parumapertus Neumann in the western United States. Appl Environ Microbiol. 2017;83. https:\/\/doi.org\/10.1128\/AEM.03463-16 PMid:28213544 PMCid:PMC5394329","DOI":"10.1128\/AEM.03463-16"},{"key":"99181","doi-asserted-by":"crossref","unstructured":"Nieri-Bastos FA, Marcili A, de Sousa R, et al. Phylogenetic evidence for the existence of multiple strains of Rickettsia parkeri in the New World. Appl Environ Microbiol. 2018;84. https:\/\/doi.org\/10.1128\/AEM.02872-17 PMid:29439989 PMCid:PMC5881050","DOI":"10.1128\/AEM.02872-17"},{"key":"99182","doi-asserted-by":"crossref","unstructured":"S\u00e1nchez-Montes S, L\u00f3pez-P\u00e9rez AM, Guzm\u00e1n-Cornejo C, et al. Rickettsia parkeri in dermacentor parumapertus ticks, Mexico. Emerg Infect Dis. 2018;24:1108-1111. https:\/\/doi.org\/10.3201\/eid2406.180058 PMid:29774838 PMCid:PMC6004873","DOI":"10.3201\/eid2406.180058"},{"key":"99183","doi-asserted-by":"crossref","unstructured":"S\u00e1nchez-Montes S, Colunga-Salas P, Lozano-Sardaneta YN, et al. The genus Rickettsia in Mexico: Current knowledge and perspectives. Ticks Tick Borne Dis. 2021;12. https:\/\/doi.org\/10.1016\/j.ttbdis.2020.101642 PMid:33388557","DOI":"10.1016\/j.ttbdis.2020.101642"},{"key":"99184","doi-asserted-by":"crossref","unstructured":"S S-M, GG B-G, A H-V, et al. Molecular Confirmation of Rickettsia parkeri in Amblyomma ovale Ticks, Veracruz, Mexico. Emerg Infect Dis [Internet]. 2019 [cited 2021 Oct 10];25:2315-2317. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/31742525\/. https:\/\/doi.org\/10.3201\/eid2512.190964 PMid:31742525 PMCid:PMC6874242","DOI":"10.3201\/eid2512.190964"},{"key":"99185","doi-asserted-by":"crossref","unstructured":"Torres-Chable OM, Jimenez-Delgadillo BG, Alvarado-Kant\u00fan YN, et al. Rickettsia parkeri (Rickettsiales: Rickettsiaceae) detected in Amblyomma maculatum ticks collected on dogs in Tabasco, Mexico. Exp Appl Acarol [Internet]. 2020 [cited 2023 Mar 8];82:431-440. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/33025238\/. https:\/\/doi.org\/10.1007\/s10493-020-00524-z PMid:33025238","DOI":"10.1007\/s10493-020-00524-z"},{"key":"99186","doi-asserted-by":"crossref","unstructured":"L\u00f3pez-P\u00e9rez AM, S\u00e1nchez-Montes S, Maya-Badillo BA, et al. Molecular detection of Rickettsia amblyommatis and Rickettsia parkeri in ticks collected from wild pigs in Campeche, Mexico. Ticks Tick Borne Dis [Internet]. 2022 [cited 2023 Mar 8];13. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/34670190\/. https:\/\/doi.org\/10.1016\/j.ttbdis.2021.101844 PMid:34670190","DOI":"10.1016\/j.ttbdis.2021.101844"},{"key":"99187","doi-asserted-by":"crossref","unstructured":"Peniche-Lara G, Lara-Perera V. Rickettsiosis Caused by Rickettsia parkeri, Mexico. Emerg Infect Dis [Internet]. 2022 [cited 2022 Feb 7];28:478-479. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/35076372\/. https:\/\/doi.org\/10.3201\/eid2802.210454 PMid:35076372 PMCid:PMC8798671","DOI":"10.3201\/eid2802.210454"},{"key":"99188","doi-asserted-by":"crossref","unstructured":"JA O, S N, Rd S, et al. [Latinamerican guidelines of RIICER for diagnosis of tick-borne rickettsioses]. Rev Chilena Infectol [Internet]. 2014 [cited 2021 Oct 9];31:54-65. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/24740776\/. https:\/\/doi.org\/10.4067\/S0716-10182014000100009 PMid:24740776","DOI":"10.4067\/S0716-10182014000100009"},{"key":"99189","doi-asserted-by":"crossref","unstructured":"A da PS, TF M, S M-L, et al. A human case of spotted fever caused by Rickettsia parkeri strain Atlantic rainforest and its association to the tick Amblyomma ovale. Parasit Vectors [Internet]. 2019 [cited 2021 Oct 10];12. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/31604442\/. https:\/\/doi.org\/10.1186\/s13071-019-3730-2 PMid:31604442 PMCid:PMC6790035","DOI":"10.1186\/s13071-019-3730-2"},{"key":"99190","unstructured":"Torres\u2010Castro M, S\u00e1nchez\u2010Montes S, Colunga\u2010Salas P, et al. Molecular confirmation of Rickettsia parkeri in humans from Southern Mexico. Zoonoses Public Health [Internet]. 2022 [cited 2022 Feb 20]; Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/35142079\/."},{"key":"99191","doi-asserted-by":"crossref","unstructured":"Abarca K, Oteo JA. [Clinical approach and main tick-borne rickettsiosis present in Latin America]. Rev Chilena Infectol [Internet]. 2014 [cited 2022 Nov 21];31:569-576. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/25491456\/. https:\/\/doi.org\/10.4067\/S0716-10182014000500009 PMid:25491456","DOI":"10.4067\/S0716-10182014000500009"},{"key":"99192","doi-asserted-by":"crossref","unstructured":"Fournier PE, Dumler JS, Greub G, et al. Gene sequence-based criteria for identification of new rickettsia isolates and description of Rickettsia heilongjiangensis sp. nov. J Clin Microbiol [Internet]. 2003 [cited 2022 Feb 16];41:5456-5465. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/14662925\/. https:\/\/doi.org\/10.1128\/JCM.41.12.5456-5465.2003 PMid:14662925 PMCid:PMC308961","DOI":"10.1128\/JCM.41.12.5456-5465.2003"},{"key":"99193","doi-asserted-by":"crossref","unstructured":"Hidalgo M, Faccini-Mart\u00ednez \u00e1lvaro A, Valbuena G. Rickettsiosis transmitidas por garrapatas en las Am\u00e9ricas: Avances cl\u00ednicos y epidemiol\u00f3gicos, y retos en el diagn\u00f3stico. Biomedica. 2013;33:161-178. https:\/\/doi.org\/10.7705\/biomedica.v33i0.1466","DOI":"10.7705\/biomedica.v33i0.1466"},{"key":"99194","doi-asserted-by":"crossref","unstructured":"Panti-May J, Panti-May JA, Torres-Castro MA, et al. ZOONOTIC PARASITES AND MICROMAMMALS IN THE YUCATAN PENINSULA, MEXICO: CONTRIBUTIONS OF THE CCBA-UADY. Tropical and Subtropical Agroecosystems [Internet]. 2021 [cited 2022 Feb 16];24. Available from: https:\/\/www.revista.ccba.uady.mx\/ojs\/index.php\/TSA\/article\/view\/3343. https:\/\/doi.org\/10.56369\/tsaes.3343","DOI":"10.56369\/tsaes.3343"},{"key":"99195","unstructured":"Scott AT, Vondrak CJ, Sanderlin AG, et al. Rickettsia parkeri. Trends Microbiol [Internet]. 2022 [cited 2022 Feb 20]; Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/35115187\/."},{"key":"99196","doi-asserted-by":"crossref","unstructured":"Armitano RI, Guillemi E, Escalada V, et al. [Spotted fever in Argentina. Description of two clinical cases]. Rev Argent Microbiol [Internet]. 2019 [cited 2022 Feb 16];51:339-344. Available from: https:\/\/pubmed.ncbi.nlm.nih.gov\/30928146\/. https:\/\/doi.org\/10.1016\/j.ram.2018.11.001 PMid:30928146","DOI":"10.1016\/j.ram.2018.11.001"},{"key":"99197","doi-asserted-by":"crossref","unstructured":"Dzul-Rosado KR, Reyes-Novelo E, Lugo-Caballero C, et al. Urban ecology of hosts and vectors of Rickettsia in a rickettsiosis-endemic city of the Yucatan peninsula, Mexico. Acta Trop. 2021;216. https:\/\/doi.org\/10.1016\/j.actatropica.2021.105832 PMid:33465349","DOI":"10.1016\/j.actatropica.2021.105832"}],"container-title":["Colombia Medica"],"original-title":[],"link":[{"URL":"https:\/\/colombiamedica.univalle.edu.co\/index.php\/comedica\/article\/download\/5779\/8378","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/colombiamedica.univalle.edu.co\/index.php\/comedica\/article\/download\/5779\/8375","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/colombiamedica.univalle.edu.co\/index.php\/comedica\/article\/download\/5779\/8401","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/colombiamedica.univalle.edu.co\/index.php\/comedica\/article\/download\/5779\/8378","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T23:51:11Z","timestamp":1777852271000},"score":1,"resource":{"primary":{"URL":"https:\/\/colombiamedica.univalle.edu.co\/index.php\/comedica\/article\/view\/5779"}},"subtitle":["Reporte de caso","A Case Report."],"short-title":[],"issued":{"date-parts":[[2025,9,30]]},"references-count":25,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2025,11,20]]}},"URL":"https:\/\/doi.org\/10.25100\/cm.v56i3.5779","relation":{},"ISSN":["1657-9534","0120-8322"],"issn-type":[{"value":"1657-9534","type":"electronic"},{"value":"0120-8322","type":"print"}],"subject":[],"published":{"date-parts":[[2025,9,30]]},"assertion":[{"value":"Yes","name":"crosschecked","label":"CrossChecked"},{"value":"Yes","name":"peer_reviewed","label":"Peer Reviewed"},{"value":"2025-9-30","name":"published","label":"Published"}]}}