{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T07:56:53Z","timestamp":1723017413261},"reference-count":29,"publisher":"S.C. JURNALUL PENTRU MEDICINA SI VIATA S.R.L","issue":"1","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JMedLife"],"abstract":"<jats:p>Gonorrhea is the second most common sexually transmitted infection spreading worldwide and a serious public health problem. How\ufffdever, further data are required to improve the management of gonorrhea.<\/jats:p>\n<jats:p>Our aim was to review the features of gonococcal infection and characterize the challenges of its management.<\/jats:p>\n<jats:p>A retrospective descriptive study of the medical records of 136 adult patients with gonorrhea that visited Ternopil Regional Sexually Transmitted Infections Clinic (Ukraine) in 2013-2018 was performed.<\/jats:p>\n<jats:p>The male-to-female ratio was 6.6:1. Homosexually-acquired gonorrhoea was 3.7%. Also, most patients acquired gonorrhea in Ukraine (98.4%). The mean infectious period lasted 2-16 days, including the incubation period of 1-9 days and the period from the onset of symptoms to the first visit of the clinic of 1-7 days. The probability of <jats:italic>N. gonorrhoeae<\/jats:italic> transmission within the frame of the epidemiologic sexual chain was 1:2.4. Concurrent <jats:italic>T. vaginalis<\/jats:italic> (39.7%) and <jats:italic>C. trachomatis<\/jats:italic> (2.2%) were detected. HIV and syphilis screening rates were 1.6% and 0.7%, respectively. The examining rate of sexual partners was 11%, testing extragenital specimens - 0.7%, screening coverage for HIV - 46.3%, compliance with follow-up visits - 41.9%. Part of patients (16.2%) received monotherapy with clarithromycin, doxycycline, benzylpenicillin, azithromycin, or ofloxacin.<\/jats:p>\n<jats:p>The management of <jats:italic>N. gonorrhoeae<\/jats:italic> infections was compromised by a low rate of examining sexual partners, females and testing extragenital specimens, screening for HIV, compliance to follow-up visits, access to nucleic acid amplification tests, and receiving questionable or even obsolete antimicrobial treatment. Therefore, more accurate and comprehensive management of gonorrhea is urgently needed in Ukraine.<\/jats:p>","DOI":"10.25122\/jml-2019-0170","type":"journal-article","created":{"date-parts":[[2022,11,18]],"date-time":"2022-11-18T07:17:04Z","timestamp":1668755824000},"page":"75-81","source":"Crossref","is-referenced-by-count":1,"title":["The Clinico-Epidemiological Profile of Patients with Gonorrhoea and Challenges in the Management of Neisseria gonorrhoeae Infection in an STI clinic, Ternopil, Ukraine (2013-2018)"],"prefix":"10.25122","volume":"13","author":[{"given":"Iryna","family":"Boiko","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Functional and Laboratory Diagnostics, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Iryna Boiko, M.D., PhD student Department of Functional and Laboratory Diagnostics I.Horbachevsky Ternopil National Medical University, 46000, Maidan Voli, 1, Ternopil, Ukraine. Phone: +380676821787 E-mail: iryna.boiko.ua@gmail.com","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Viorika","family":"Akimova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Clinical Laboratory Diagnostic, Danylo Halytsky Lviv National Medical University, Lviv, Ukraine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lyudmyla","family":"Mazur","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Clinical Immunology, Allergology and General Patients\u2019 Care, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine;","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iryna","family":"Savchenko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"First Department of Internal Medicine, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine;","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ihor","family":"Kohut","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Infectious Diseases with Epidemiology, Skin and Sexually Transmitted Diseases, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine.","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Inna","family":"Krynytska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Functional and Laboratory Diagnostics, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10755","published-online":{"date-parts":[[2020,1]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","unstructured":"1. Unemo M, Seifert HS, Hook EW 3rd, Hawkes S, Ndowa F, Dillon JR. Gonorrhoea. Nat Rev Dis Primers. 2019;5(1):79.","DOI":"10.1038\/s41572-019-0128-6"},{"key":"ref2","doi-asserted-by":"crossref","unstructured":"2. 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Geneva: World Health Organization Document Production Services; 2013. p. 21-53."}],"container-title":["Journal of Medicine and Life"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/medandlife.org\/wp-content\/uploads\/JMedLife-13-75.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,18]],"date-time":"2022-11-18T07:18:02Z","timestamp":1668755882000},"score":1,"resource":{"primary":{"URL":"https:\/\/medandlife.org\/wp-content\/uploads\/JMedLife-13-75.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1]]},"references-count":29,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1]]}},"alternative-id":["JMedLife-13-75"],"URL":"https:\/\/doi.org\/10.25122\/jml-2019-0170","relation":{},"ISSN":["1844-122X","1844-3117"],"issn-type":[{"type":"print","value":"1844-122X"},{"type":"electronic","value":"1844-3117"}],"subject":[],"published":{"date-parts":[[2020,1]]}}}