{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T12:19:14Z","timestamp":1788092354772,"version":"build-2803163510"},"reference-count":4,"publisher":"S.C. JURNALUL PENTRU MEDICINA SI VIATA S.R.L","issue":"3","license":[{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JMedLife"],"abstract":"<jats:p>Finding neuroprotective agents to counteract the deleterious effects of hypoxia on neuronal cells successfully is one of the most critical targets of clinical research since preclinical studies have identified potential neuroprotective strategies. In clinical practice, amantadine and piracetam are used with reasonable success. We present the cases of three patients with acute brain hypoxia secondary to cardiac arrest, to whom Cerebrolysin was added to the standard neuroprotective treatment regimen, leading to a notable improvement in functional outcome.<\/jats:p>","DOI":"10.25122\/jml-2019-1007","type":"journal-article","created":{"date-parts":[[2019,11,15]],"date-time":"2019-11-15T10:40:16Z","timestamp":1573814416000},"page":"233-235","source":"Crossref","is-referenced-by-count":5,"title":["Neurotrophic Factors in the Treatment of Acute Brain Hypoxia Secondary to Cardiac Arrest: a Case Report"],"prefix":"10.25122","volume":"12","author":[{"given":"D","family":"W\u0119grzyn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Anesthesiology and Intensive Care Department, Maria Sklodowska-Curie\u2019s District Hospital, Skarzysko Kamienna, Poland","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Dariusz W\u0119grzyn - Head of Intensive Care Unit, Maria Sklodowska-Curie\u2019s District Hospital, Skarzysko Kamienna, Poland; E-mail: dariuszwegrzyn@poczta.onet.pl","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Kutwin-Chojnacka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Anesthesiology and Intensive Care Department, Maria Sklodowska-Curie\u2019s District Hospital, Skarzysko Kamienna, Poland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Bilski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Anesthesiology and Intensive Care Department, Maria Sklodowska-Curie\u2019s District Hospital, Skarzysko Kamienna, Poland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K","family":"Mroszczyk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Danylo Halytskyi, Lviv National Medical University, Lviv, Ukraine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K","family":"W\u0119grzyn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Danylo Halytskyi, Lviv National Medical University, Lviv, Ukraine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10755","published-online":{"date-parts":[[2019,7]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","unstructured":"A. Guekht et al., \u201cSafety and efficacy of Cerebrolysin in motor function recovery after stroke: a meta-analysis of the CARS trials,\u201d Neurol Sci, 38 10, pp. 1761\u20131769, 2017.","DOI":"10.1007\/s10072-017-3037-z"},{"key":"ref2","doi-asserted-by":"crossref","unstructured":"D. F. Muresanu, S. Strilciuc, and A. Stan, \u201cCurrent Drug Treatment of Acute Ischemic Stroke: Challenges and Opportunities,\u201d CNS Drugs, Sep. 2019.","DOI":"10.1007\/s40263-019-00663-x"},{"key":"ref3","doi-asserted-by":"crossref","unstructured":"W. Poon et al., \u201cSafety and efficacy of Cerebrolysin in acute brain injury and neurorecovery: CAPTAIN I-a randomized, placebo-controlled, double-blind, Asian-Pacific trial,\u201d Neurol. Sci., Sep. 2019.","DOI":"10.1007\/s10072-019-04053-5"},{"key":"ref4","doi-asserted-by":"crossref","unstructured":"D. F. Muresanu et al., \u201cCerebrolysin and Recovery After Stroke (CARS): A Randomized, Placebo-Controlled, Double-Blind, Multicenter Trial,\u201d Stroke, 47, 1, pp. 151\u2013159, Jan. 2016.","DOI":"10.1161\/STROKEAHA.115.009416"}],"container-title":["Journal of Medicine and Life"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/medandlife.org\/wp-content\/uploads\/JMedLife-12-233.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,24]],"date-time":"2021-12-24T03:41:49Z","timestamp":1640317309000},"score":1,"resource":{"primary":{"URL":"https:\/\/medandlife.org\/wp-content\/uploads\/JMedLife-12-233.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7]]},"references-count":4,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,7]]}},"alternative-id":["JMedLife-12-233"],"URL":"https:\/\/doi.org\/10.25122\/jml-2019-1007","relation":{},"ISSN":["1844-122X","1844-3117"],"issn-type":[{"value":"1844-122X","type":"print"},{"value":"1844-3117","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,7]]}}}