{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T07:57:57Z","timestamp":1723017477262},"reference-count":20,"publisher":"S.C. JURNALUL PENTRU MEDICINA SI VIATA S.R.L","issue":"3","license":[{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JMedLife"],"abstract":"<jats:p>Owing to the early tooth loss in a large population, the need for removable prosthodontic therapy has widely increased. Loss of teeth can occur due to trauma, periodontal disease, dental caries, and\/or oral health negligence. The removable prosthesis is preferred over other teeth replacement methods owing to its cost-effectiveness. However, due to continuous alveolar bone resorption, relining of the removable prosthesis is needed regularly. We aimed to assess the prevalence of vitamin D deficiency and bone turnover marker concerning bone mineral density. Eighty complete denture wearers either in the maxilla or in the mandible or both constituted the study sample. Before the study, all subjects were explained the procedures of the study, and informed consent was obtained before proceeding with the study. Subjects were instructed to provide an early morning sample in a fasting state as serum osteocalcin (OCN) and C-terminal telopeptide (C-Tx) have diurnal variations. Blood samples were collected, and samples were ruled out for 25-OH vitamin D, serum OCN, and C-TX. To determine the association between frequency of relining and bone turnover marker, the collected data were subjected to statistical evaluation. Significant correlations were seen between bone C-Tx, turnover markers (p&lt;0.001), and frequency of denture relining and osteocalcin (p&lt;0.001). No statistically significant effect of gender, vitamin D levels, age, calcium levels, vitamin D supplements, and diabetes was seen on denture relining frequency. The present study concludes that an elevated level of the bone turnover markers such as OCN and C-Tx increases the frequency of relining.<\/jats:p>","DOI":"10.25122\/jml-2020-0113","type":"journal-article","created":{"date-parts":[[2021,10,15]],"date-time":"2021-10-15T01:44:15Z","timestamp":1634262255000},"page":"397-401","source":"Crossref","is-referenced-by-count":0,"title":["Prevalence of vitamin D inadequacy and bone turnover markers concerning bone mineral density in older persons"],"prefix":"10.25122","volume":"14","author":[{"given":"Abhinav","family":"Jha","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Oral Pathology and Microbiology, Sarjug Dental College and Hospital, Darbhanga, Bihar, India","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aditi Singh","family":"Tanwar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Laxmi Dental Clinic, Varanasi, India","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Aditi Singh Tanwar, MDS (Pedodontics and Preventive Dentistry), Consultant, Laxmi Dental Clinic, Varanasi, India. E-mail: drpriyakasture@gmail.com","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manish","family":"Bhargava","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Oral Pathology and Microbiology, Manav Rachna Dental College, Faridabad, Haryana, India","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anil","family":"Raj","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Public Health Dentistry, Sarjug Dental College and Hospital, Darbhanga, Bihar, India","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shrimant","family":"Raman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Prosthodontics and Crown and Bridge, Sarjug Dental College and Hospital, Darbhanga, Bihar, India","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vishal","family":"Patil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Prosthodontics and Crown and Bridge, Vasantdada Patil Dental College, Sangli, Maharashtra, India","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10755","published-online":{"date-parts":[[2021,6]]},"reference":[{"key":"ref1","unstructured":"Beltran-Aguilar ED, Barker LK, Canto MT, et al. Surveillance for dental caries, dental sealants, tooth retention, Edentulism, and enamel fluorosis \u2013 United States, 1988\u20131994 and 1999\u20132002. MMWR Surveill Summ 2005; 54(3):1\u201343."},{"key":"ref2","doi-asserted-by":"crossref","unstructured":"Groen JJ, Duyuensz F, Halstead JA. Diffuse alveolar atrophy of jaw and presenile osteoporosis. Gerontol. Clin 2; 68\u201386,1960.","DOI":"10.1159\/000244610"},{"key":"ref3","unstructured":"Nussbaum PE. Atrophy of alveolar bone as a precursor sign of presenile osteoporosis. Schweiz Monatsschr Zahnheilkd. 81;1069\u20131098,1971."},{"key":"ref4","doi-asserted-by":"crossref","unstructured":"Ross PD, Knowlton W.Rapid bone loss is associated with increased levels of biochemical markers. J Bone Miner Res. 1998;13(2):297\u2013302.","DOI":"10.1359\/jbmr.1998.13.2.297"},{"key":"ref5","doi-asserted-by":"crossref","unstructured":"Garnero P. Biomarkers for osteoporosis management: utility in diagnosis, fracture risk prediction, and therapy monitoring. Mol Diagn Ther. 2008;12(3):157\u201370.","DOI":"10.1007\/BF03256280"},{"key":"ref6","doi-asserted-by":"crossref","unstructured":"Holick MF. High Prevalence of Vitamin D Inadequacy and Implications for Health.Mayo Clin Proc. 2006; 81:353\u2013373.","DOI":"10.4065\/81.3.353"},{"key":"ref7","doi-asserted-by":"crossref","unstructured":"Atwood DA. Reduction of residual ridges: a major oral disease entity. J Prosthet Dent. 1971; 26:266\u2013279.","DOI":"10.1016\/0022-3913(71)90069-2"},{"key":"ref8","doi-asserted-by":"crossref","unstructured":"Carlsson GE, Bergman B, Hedegard B. Changes in the contour of the maxillary alveolar process under immediate dentures. A longitudinal clinical and x-ray cephalometric study covering 5 years. Acta Odontol Scand. 1967;25:45\u201375.","DOI":"10.3109\/00016356709072522"},{"key":"ref9","doi-asserted-by":"crossref","unstructured":"Atwood DA. Some clinical factors are related to the rate of resorption of residual ridges. J Prosthet Dent. 2001; 86(2):119\u201325.","DOI":"10.1067\/mpr.2001.117609"},{"key":"ref10","doi-asserted-by":"crossref","unstructured":"Atwood DA, Coy WA. Clinical, cephalometric, and densitometry study of reduction of residual ridges. J Prosthet Dent. 1971; 26:28\u2013295.","DOI":"10.1016\/0022-3913(71)90070-9"},{"key":"ref11","doi-asserted-by":"crossref","unstructured":"Tallgren A. The continuing reduction of the residual alveolar ridges in complete denture wearers: a mixed-longitudinal study covering 25 years. J Prosthet Dent. 1972; 27:120\u2013132.","DOI":"10.1016\/0022-3913(72)90188-6"},{"key":"ref12","doi-asserted-by":"crossref","unstructured":"Tallgren A. Positional changes of complete dentures. A 7-year longitudinal study. Acta Odontol Scand. 1969; 27:539\u2013561.","DOI":"10.3109\/00016356908994049"},{"key":"ref13","doi-asserted-by":"crossref","unstructured":"Schlosser RO. Basic factors retarding resorptive changes of residual ridges under complete denture prostheses. J Am Dent Assoc. 1950; 40:12\u201319.","DOI":"10.14219\/jada.archive.1950.0020"},{"key":"ref14","doi-asserted-by":"crossref","unstructured":"Lammie GA. The reduction of the edentulous ridges. J Prosthet Dent. 1960; 10:605\u2013611.","DOI":"10.1016\/0022-3913(60)90239-0"},{"key":"ref15","doi-asserted-by":"crossref","unstructured":"Atwood DA. Some clinical factors related to the rate of resorption of residual ridges. J Prosthet Dent. 1962; 12:441\u2013450.","DOI":"10.1016\/0022-3913(62)90125-7"},{"key":"ref16","doi-asserted-by":"crossref","unstructured":"Kingsmill VJ, Post extraction remodeling of the adult mandible. Crit Rev Oral Biol Med 1999; 10:384\u2013404.","DOI":"10.1177\/10454411990100030801"},{"key":"ref17","doi-asserted-by":"crossref","unstructured":"Wical KE, Brussee P. Effects of a calcium and vitamin D supplement on alveolar ridge resorption in immediate denture patients. Prosthet Dent. 1979; 41:4\u201311.","DOI":"10.1016\/0022-3913(79)90347-0"},{"key":"ref18","doi-asserted-by":"crossref","unstructured":"Vestergaard P. Diabetes and Bone. J Diabetes Metab. 2011; S1:001.","DOI":"10.4172\/2155-6156.S1-001"},{"key":"ref19","unstructured":"Kalk W, Denissen HW, Kayser AF. Preventive goals in oral implantology. Int Dent J. 1993; 43:483\u201391."},{"key":"ref20","unstructured":"Sanfilippo F, Bianchi AE. Osteoporosis: the effect on maxillary bone resorption and therapeutic possibilities by means of implant prostheses \u2013 a literature review and clinical considerations. Int J Periodontics Restorative Dent. 2003; 23:447\u201357."}],"container-title":["Journal of Medicine and Life"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/medandlife.org\/wp-content\/uploads\/JMedLife-14-397.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,15]],"date-time":"2021-10-15T01:46:00Z","timestamp":1634262360000},"score":1,"resource":{"primary":{"URL":"https:\/\/medandlife.org\/wp-content\/uploads\/JMedLife-14-397.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6]]},"references-count":20,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["JMedLife-14-397"],"URL":"https:\/\/doi.org\/10.25122\/jml-2020-0113","relation":{},"ISSN":["1844-122X","1844-3117"],"issn-type":[{"type":"print","value":"1844-122X"},{"type":"electronic","value":"1844-3117"}],"subject":[],"published":{"date-parts":[[2021,6]]}}}