{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T22:09:06Z","timestamp":1788905346277,"version":"build-2803163510"},"reference-count":13,"publisher":"S.C. JURNALUL PENTRU MEDICINA SI VIATA S.R.L","issue":"4","license":[{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JMedLife"],"abstract":"<jats:p>Osteogenesis imperfecta (OI) is a genetically determined systemic pathology that involves a disturbance in the synthesis of type one collagen and is mainly characterized by bone brittleness and other abnormalities. The musculoskeletal system is the most affected by bone fracture after mild mechanical stress occurs. Pathologic bowing appears without trauma, and hyperlaxity is jeopardizing joint stability. Having such an abrupt debut, some patients report in-utero fractures, and treatment is very challenging since surgery has to be postponed until the children grow and become good candidates for intramedullary nailing. In this paper, we discuss the experience of \u201cGrigore Alexandrescu\u201d Hospital for Children in treating these patients and the results we obtained regarding the revision surgeries that we had done. Revision surgery is mandatory for OI patients, and there are multiple factors in deciding to use an implant. We looked back at the data collected for those cases where revision was not related to infection, trauma, or disengagement of the male-female system due to the overlengthening of the implant. The conclusions made are comparable to other centers worldwide with respect to lower limb surgery, and we changed the management protocol according to the problems encountered.<\/jats:p>","DOI":"10.25122\/jml-2020-0161","type":"journal-article","created":{"date-parts":[[2022,11,18]],"date-time":"2022-11-18T08:33:11Z","timestamp":1668760391000},"page":"543-547","source":"Crossref","is-referenced-by-count":6,"title":["Revision Rates for Osteogenesis Imperfecta Patients Treated with Telescopic Nails. A follow-up Study After a 7-year Experience"],"prefix":"10.25122","volume":"13","author":[{"given":"Alin Gabriel","family":"Sterian","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of Pediatric Orthopedics, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Alin Gabriel Sterian, MD, Department of Pediatric Orthopedics, Carol Davila University of Medicine and Pharmacy,37 Dionisie Lupu, 050474, Bucharest, Romania.E-mail: drsterian@gmail.com","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandru","family":"Ulici","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of Pediatric Orthopedics, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10755","published-online":{"date-parts":[[2020,10]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","unstructured":"1. Sillence DO, Senn A, Danks DM. Genetic heterogeneity in osteogenesis imperfecta. J Med Genet. 1979; 16:101-16.","DOI":"10.1136\/jmg.16.2.101"},{"key":"ref2","doi-asserted-by":"crossref","unstructured":"2. Forlino A, Cabral WA, Barnes AM, Marini JC. New perspectives on osteogenesis imperfecta. Nat Rev Endocrinol. 2011; 7:540-57.","DOI":"10.1038\/nrendo.2011.81"},{"key":"ref3","doi-asserted-by":"crossref","unstructured":"3. Van Dijk FS, Sillence DO. 2014. Osteogenesis imperfecta: Clinical diagnosis, nomenclature and severity assessment. Am J Med Genet Part A 164A:1470\u20131481.","DOI":"10.1002\/ajmg.a.36545"},{"key":"ref4","unstructured":"4. Bailey RW, Dubow HI. Studies of longitudinal bone growth resulting in an extensible nail. Surg Forum. 1963;14:455\u2013458."},{"key":"ref5","doi-asserted-by":"crossref","unstructured":"5. Nicolaou N, Bowe JD, Wilkinson JM, Fernandes JA, Bell MJ. Use of the Sheffield telescopic intramedullary rod system for the management of osteogenesis imperfecta: clinical outcomes at an average follow-up of nineteen years. J Bone Joint Surg Am. 2011;93-A(21):1994\u20132000.","DOI":"10.2106\/JBJS.J.01893"},{"key":"ref6","doi-asserted-by":"crossref","unstructured":"6. Ruck J, Dahan-Oliel N, Montpetit K, Rauch F, Fassier F. Fassier- Duval femoral rodding in children with osteogenesis imperfecta receiving bisphosphonates: functional outcomes at one year. J Child Orthop. 2011;5(3):217-224. doi:10.1007\/s11832-011-0341-7.","DOI":"10.1007\/s11832-011-0341-7"},{"key":"ref7","doi-asserted-by":"crossref","unstructured":"7. Scollan JP, Jauregui JJ, Jacobsen CM, et al. The outcomes of nonelongating intramedullary fixation of the lower extremity for pediatric osteogenesis imperfecta patients: a meta-analysis. J Pediatr Orthop. 2017;37:e313\u2013e316.","DOI":"10.1097\/BPO.0000000000000970"},{"key":"ref8","unstructured":"8. Bone plating in patients with type III osteogenesis imperfecta: results and complications. Enright WJ, Noonan KJ.; Iowa Orthop J. 2006;26:37-40. PMCID: PMC1888596."},{"key":"ref9","unstructured":"9. https:\/\/www.pegamedical.com\/medias\/iw\/FD_surg_tech_revJ_FD-ST-EN.pdf."},{"key":"ref10","doi-asserted-by":"crossref","unstructured":"10. Ruck J, Dahan-Oliel N, Montpetit K, Rauch F, Fassier F. Fassier- Duval femoral rodding in children with osteogenesis imperfecta receiving bisphosphonates: functional outcomes at one year. J Child Orthop. 2011;5(3):217-224. doi:10.1007\/s11832-011-0341-7.","DOI":"10.1007\/s11832-011-0341-7"},{"key":"ref11","doi-asserted-by":"crossref","unstructured":"11. Sofield HA, Millar EA. Fragmentation, realignment, and intra-medullary rod fixation of deformities of the long bones in children: a ten year appraisal. J Bone Joint Surg Am. 1959;41-A(8):1371\u20131391.","DOI":"10.2106\/00004623-195941080-00001"},{"key":"ref12","doi-asserted-by":"crossref","unstructured":"12. Su\u0142ko J, Oberc A. Advantages and Complications Following Fassier-Duval Intramedullary Rodding in Children. Pilot Study. Ortop Traumatol Rehabil. 2015;17(5):523-530. doi:10.5604\/15093492.1186830.","DOI":"10.5604\/15093492.1186830"},{"key":"ref13","doi-asserted-by":"crossref","unstructured":"13. Cox I, Al Mouazzen L, Bleibleh S, et al. Combined two-centre experience of single-entry telescopic rods identifies characteristic modes of failure. Bone Joint J. 2020;102-B(8):1048-1055. doi:10.1302\/0301-620X.102B8.BJJ-2020-0131.R1.","DOI":"10.1302\/0301-620X.102B8.BJJ-2020-0131.R1"}],"container-title":["Journal of Medicine and Life"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/medandlife.org\/wp-content\/uploads\/JMedLife-13-543.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,18]],"date-time":"2022-11-18T08:33:18Z","timestamp":1668760398000},"score":1,"resource":{"primary":{"URL":"https:\/\/medandlife.org\/wp-content\/uploads\/JMedLife-13-543.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10]]},"references-count":13,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,10]]}},"alternative-id":["JMedLife-13-543"],"URL":"https:\/\/doi.org\/10.25122\/jml-2020-0161","relation":{},"ISSN":["1844-122X","1844-3117"],"issn-type":[{"value":"1844-122X","type":"print"},{"value":"1844-3117","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10]]}}}