{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T01:24:29Z","timestamp":1787793869116,"version":"build-2784847793"},"reference-count":11,"publisher":"S.C. JURNALUL PENTRU MEDICINA SI VIATA S.R.L","issue":"1","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JMedLife"],"abstract":"<jats:p>This case report describes a rare case of progressive muscle weakness in a patient treated for eosinophilic fasciitis (EF) for many years before being diagnosed with a second autoimmune disease: dermatomyositis. Our case is a report of a 65-year-old male diagnosed with eosinophilic fasciitis 7 years before being evaluated in our service at Mayo Clinic in Jacksonville, Florida, due to progressive muscle weakness despite the chronic treatment with methotrexate. Contrast-enhanced magnetic resonance imaging of the lower extremity showed enhancement throughout the thigh musculature, which led us to pursue biopsies of the fascia and muscle in order to confirm the diagnosis of EF associated with myopathy. This case illustrates the need to consider the possibility of myopathy in patients diagnosed with EF whenever muscle weakness is more prominent than expected.<\/jats:p>","DOI":"10.25122\/jml-2021-0015","type":"journal-article","created":{"date-parts":[[2021,4,16]],"date-time":"2021-04-16T07:38:49Z","timestamp":1618558729000},"page":"121-124","source":"Crossref","is-referenced-by-count":3,"title":["Not just eosinophilic fasciitis"],"prefix":"10.25122","volume":"14","author":[{"given":"Razvan","family":"Chirila","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of Internal Medicine, Mayo Clinic, Jacksonville, Florida, United States of America","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena Raluca","family":"Cristea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Faculty of Medicine, Complutense University of Madrid, Spain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica Roxana","family":"Purcarea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of Nephrology, \u201cCarol Davila\u201d Clinical Nephrology Hospital, Bucharest, Romania","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura Carina","family":"Tribus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of Gastroenterology, Bucharest Emergency University Hospital","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"\u201cCarol Davila\u201d University of Medicine and Pharmacy, Bucharest, Romania","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"* Corresponding Author: Laura Carina Tribus, MD Emergency University Hospital of Bucharest 169 Independentei Avenue, 050098 Bucharest, Romania. Phone: +40745105155. E-mail: ltribusro@yahoo.com","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10755","published-online":{"date-parts":[[2021,1]]},"reference":[{"key":"ref1","unstructured":"1. Rodnan GP, DiBartolomeo A, Medsger TA, Jr. Proceedings: Eosinophilic fasciitis. Report of six cases of a newly recognized scleroderma-like syndrome. Arthritis Rheum. 1975 Sep-Oct; 18(5):525."},{"key":"ref2","doi-asserted-by":"crossref","unstructured":"2. Doyle JA, Ginsburg WW. Eosinophilic fasciitis. Med Clin North Am. 1989 Sep; 73(5):1157\u20131166.","DOI":"10.1016\/S0025-7125(16)30625-3"},{"key":"ref3","unstructured":"3. Varga J, Griffin R, Newman JH, Jimenez SA. Eosinophilic fasciitis is clinically distinguishable from the eosinophilia-myalgia syndrome and is not associated with L-tryptophan use. J Rheumatol. 1991 Feb; 18(2):259\u2013263."},{"key":"ref4","doi-asserted-by":"crossref","unstructured":"4. Dalakas MC, Hohlfeld R. Polymyositis and dermatomyositis. Lancet. 2003 Sep 20; 362(9388):971\u2013982.","DOI":"10.1016\/S0140-6736(03)14368-1"},{"key":"ref5","doi-asserted-by":"crossref","unstructured":"5. Plotz PH, Dalakas M, Leff RL, Love LA, Miller FW, Cronin ME. Current concepts in the idiopathic inflammatory myopathies: polymyositis, dermatomyositis, and related disorders. Ann Intern Med. 1989 Jul 15; 111(2):143\u2013157.","DOI":"10.7326\/0003-4819-111-2-143"},{"key":"ref6","doi-asserted-by":"crossref","unstructured":"6. Dobloug C, Garen T, Bitter H. Prevalence and clinical characteristics of adult polymyositis and derm atomyositis; data from a large and unselected Norwegian cohort. Annals of the Rheumatic Diseases 2015;74:1551\u20131556.","DOI":"10.1136\/annrheumdis-2013-205127"},{"key":"ref7","doi-asserted-by":"crossref","unstructured":"7. Berianu F, Cohen MD, Abril A, Ginsburg WW. Eosinophilic fasciitis: clinical characteristics and response to methotrexate. Int J Rheum Dis. 2014 Dec 20.","DOI":"10.1111\/1756-185X.12499"},{"key":"ref8","doi-asserted-by":"crossref","unstructured":"8. Helfgott SM, BVarga J. Eosinophilic fasciitis. An Bras Dermatol. 2016 Sep-Oct; 91(5 Suppl 1).","DOI":"10.1590\/abd1806-4841.20164683"},{"key":"ref9","doi-asserted-by":"crossref","unstructured":"9. Allen JA, Peterson A, Sufit R, Hinchcliff ME, Mahoney JM, Wood TA, et al. Post-epidemic eosinophilia-myalgia syndrome associated with L-tryptophan. Arthritis Rheum. 2011 Nov; 63(11):3633\u20133639.","DOI":"10.1002\/art.30514"},{"key":"ref10","doi-asserted-by":"crossref","unstructured":"10. Moulton SJ, Kransdorf MJ, Ginsburg WW, Abril A, Persellin S. Eosinophilic fasciitis: spectrum of MRI findings. AJR Am J Roentgenol. 2005 Mar; 184(3):975\u2013978.","DOI":"10.2214\/ajr.184.3.01840975"},{"key":"ref11","doi-asserted-by":"crossref","unstructured":"11. Levine TD. Rituximab in the treatment of dermatomyositis: an open-label pilot study. Arthritis Rheum. 2005 Feb; 52(2):601\u2013607.","DOI":"10.1002\/art.20849"}],"container-title":["Journal of Medicine and Life"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/medandlife.org\/wp-content\/uploads\/21.-jml-2021-0015.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,16]],"date-time":"2021-04-16T07:39:28Z","timestamp":1618558768000},"score":1,"resource":{"primary":{"URL":"https:\/\/medandlife.org\/wp-content\/uploads\/21.-jml-2021-0015.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["JMedLife-14-121"],"URL":"https:\/\/doi.org\/10.25122\/jml-2021-0015","relation":{},"ISSN":["1844-122X","1844-3117"],"issn-type":[{"value":"1844-122X","type":"print"},{"value":"1844-3117","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1]]}}}