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Donegan S Novel treatment for the management of ifosfamide neurotoxicity: Rationale for the use of methylene blue J Oncol Pharm Pract 200164153165 10.1177\/107815520100600404","journal-title":"J Oncol Pharm Pract"},{"issue":"9","key":"ref26","doi-asserted-by":"publisher","first-page":"1254","DOI":"10.7150\/ijbs.4679","article-title":"Interleukin-6, a major cytokine in the central nervous system","volume":"8","author":"Erta M Quintana A Hidalgo J","year":"2012","unstructured":"26. 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Al-hussainy HA AL-Biati HA Ali IS The Effect of Nefopam Hydrochloride on the Liver, Heart, and Brain of Rats: Acute Toxicity and Mechanisms of Nefopam Toxicity J Pharm Negative Results 2022133393 10.47750\/pnr.2022.13.03.061","journal-title":"J Pharm Negative Results"},{"issue":"3","key":"ref28","doi-asserted-by":"publisher","first-page":"1308","DOI":"10.1080\/01480545.2020.1822390","article-title":"The protective effect of Morin against ifosfamide-induced acute liver injury in rats associated with the inhibition of DNA damage and apoptosis","volume":"45","author":"\u00d6zdemir S Kucukler S \u00c7omakl\u0131 S Kandemir FM","year":"2022","unstructured":"28. \u00d6zdemir S Kucukler S \u00c7omakl\u0131 S Kandemir FM The protective effect of Morin against ifosfamide-induced acute liver injury in rats associated with the inhibition of DNA damage and apoptosis Drug Chem Toxicol 202245313081317 10.1080\/01480545.2020.1822390","journal-title":"Drug Chem Toxicol"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"45673","DOI":"10.1155\/2007\/45673","article-title":"Anti-inflammatory effects of flavonoids: genistein, kaempferol, quercetin, and daidzein inhibit STAT-1 and NF-kappaB activations, whereas flavone, isorhamnetin, naringenin, and pelargonidin inhibit only NF-kappaB activation along with their inhibitory effect on iNOS expression and NO production in activated macrophages","volume":"2007","author":"H\u00e4m\u00e4l\u00e4inen M Nieminen R Vuorela P Heinonen M Moilanen E","year":"2007","unstructured":"29. 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Beshna E Alwafi SA Lazrak RR Evaluation of the Quality of life of Zawia (Libya) patients undergoing hemodialysis Med Pharm J 202321416 10.55940\/medphar202229","journal-title":"Med Pharm J"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"108","DOI":"10.3390\/nu8060361","article-title":"Isoflavone genistein and daidzein up-regulate lps-induced inducible nitric oxide synthase activity through estrogen receptor pathway in raw2647 cells","volume":"71","author":"Nakaya M Tachibana H Yamada K","year":"2005","unstructured":"31. Nakaya M Tachibana H Yamada K Isoflavone genistein and daidzein up-regulate lps-induced inducible nitric oxide synthase activity through estrogen receptor pathway in raw2647 cells Biochem. Pharmacol 2005 71108114 10.3390\/nu8060361","journal-title":"Biochem. 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Meng H Fu G Shen J Shen K Ameliorative Effect of Daidzein on Cisplatin-Induced Nephrotoxicity in Mice via Modulation of Inflammation, Oxidative Stress, and Cell Death Oxid Med Cell Longev 201720173140680 10.1155\/2017\/3140680","journal-title":"Oxid Med Cell Longev"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1016\/j.neuro.2019.11.004","article-title":"Morin attenuates ifosfamide-induced neurotoxicity in rats via suppression of oxidative stress, neuroinflammation and neuronal apoptosis","volume":"76","author":"\u00c7elik H Kucukler S \u00c7omakl\u0131 S \u00d6zdemir S","year":"2020","unstructured":"35. \u00c7elik H Kucukler S \u00c7omakl\u0131 S \u00d6zdemir S Morin attenuates ifosfamide-induced neurotoxicity in rats via suppression of oxidative stress, neuroinflammation and neuronal apoptosis Neurotoxicology 2020 76 12637 10.1016\/j.neuro.2019.11.004","journal-title":"Neurotoxicology"},{"issue":"10","key":"ref36","doi-asserted-by":"publisher","first-page":"4594","DOI":"10.52711\/0974-360X.2022.00771","article-title":"Panax ginseng as Antioxidant and Anti-inflammatory to reduce the Cardiotoxicity of Doxorubicin on rat module","volume":"15","author":"Al-Hussaniy HA Mohammed ZN Alburghaif AH Naji MA","year":"2022","unstructured":"36. Al-Hussaniy HA Mohammed ZN Alburghaif AH Naji MA Panax ginseng as Antioxidant and Anti-inflammatory to reduce the Cardiotoxicity of Doxorubicin on rat module Res J Pharm Tech 202215104594600 10.52711\/0974-360X.2022.00771","journal-title":"Res J Pharm Tech"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"981","DOI":"10.1016\/j.biopha.2018.06.048","article-title":"Therapeutic efficacy of zingerone against vancomycin-induced oxidative stress, inflammation, apoptosis and aquaporin 1 permeability in rat kidney","volume":"105","author":"Kandemir FM Yildirim S Kucukler S Caglayan C","year":"2018","unstructured":"37. Kandemir FM Yildirim S Kucukler S Caglayan C Therapeutic efficacy of zingerone against vancomycin-induced oxidative stress, inflammation, apoptosis and aquaporin 1 permeability in rat kidney Biomed Pharmacother 2018105981991 10.1016\/j.biopha.2018.06.048","journal-title":"Biomed Pharmacother"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"650","DOI":"10.1016\/j.fct.2017.12.017","article-title":"Chrysin attenuates testosterone-induced benign prostate hyperplasia in rats","volume":"111","author":"Shoieb SM Esmat A Khalifa AE Abdel-Naim AB","year":"2018","unstructured":"38. Shoieb SM Esmat A Khalifa AE Abdel-Naim AB Chrysin attenuates testosterone-induced benign prostate hyperplasia in rats Food Chem Toxicol 2018111650659 10.1016\/j.fct.2017.12.017","journal-title":"Food Chem Toxicol"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1186\/1742-2094-9-175","article-title":"JNK signaling is the shared pathway linking neuroinflammation, blood-brain barrier disruption, and oligodendroglial apoptosis in the white matter injury of the immature brain","volume":"9","author":"Wang LW Tu YF Huang CC Ho CJ","year":"2012","unstructured":"39. Wang LW Tu YF Huang CC Ho CJ JNK signaling is the shared pathway linking neuroinflammation, blood-brain barrier disruption, and oligodendroglial apoptosis in the white matter injury of the immature brain J Neuroinflammation 2012 9175 10.1186\/1742-2094-9-175","journal-title":"J Neuroinflammation"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"905828","DOI":"10.3389\/fphar.2022.905828","article-title":"Combination of Panax ginseng CA Mey and Febuxostat Boasted Cardioprotective Effects Against Doxorubicin-Induced Acute Cardiotoxicity in Rats","volume":"13","author":"Al-Kuraishy HM Al-Hussaniy HA Al-Gareeb AI Negm WA","year":"2022","unstructured":"40. Al-Kuraishy HM Al-Hussaniy HA Al-Gareeb AI Negm WA Combination of Panax ginseng CA Mey and Febuxostat Boasted Cardioprotective Effects Against Doxorubicin-Induced Acute Cardiotoxicity in Rats Front Pharmacol 202213 905828905828 10.3389\/fphar.2022.905828","journal-title":"Front Pharmacol"},{"issue":"1","key":"ref41","doi-asserted-by":"crossref","first-page":"27","DOI":"10.31351\/vol21iss1pp27-33","article-title":"Protective Effect of Ginger Extract Against Cisplatin-Induced Hepatotoxicity and Cardiotoxicity in Rats","volume":"21","author":"Attyah AM Ismail SH","year":"2012","unstructured":"41. 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