{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T01:31:02Z","timestamp":1792978262143,"version":"4.5.0"},"reference-count":46,"publisher":"S.C. JURNALUL PENTRU MEDICINA SI VIATA S.R.L","issue":"6","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JMedLife"],"DOI":"10.25122\/jml-2024-0322","type":"journal-article","created":{"date-parts":[[2024,10,29]],"date-time":"2024-10-29T11:11:02Z","timestamp":1730200262000},"page":"549-554","source":"Crossref","is-referenced-by-count":11,"title":["MiRNAs as potential biomarkers in early breast cancer detection: a systematic review"],"prefix":"10.25122","volume":"17","author":[{"given":"Ana-Maria","family":"Mihai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Polizu Department, Alessandrescu-Rusescu National Institute for Mother and Child Health, Bucharest, Romania","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura Maria","family":"Ianculescu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Polizu Department, Alessandrescu-Rusescu National Institute for Mother and Child Health, Bucharest, Romania","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolae","family":"Suciu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Polizu Department, Alessandrescu-Rusescu National Institute for Mother and Child Health, Bucharest, Romania","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Carol Davila University of Medicine and Pharmacy, Bucharest, Romania","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10755","published-online":{"date-parts":[[2024,6]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1186\/s13578-016-0071-0","article-title":"miRNAs as potential biomarkers in early breast cancer detection following mammography","volume":"6","author":"Fu SW, Lee W, Coffey C, Lean A, Wu X, Tan X","year":"2016","unstructured":"1. Fu SW, Lee W, Coffey C, Lean A, Wu X, Tan X, miRNAs as potential biomarkers in early breast cancer detection following mammography, Cell Biosci, 2016;66","journal-title":"Cell Biosci"},{"issue":"2","key":"ref2","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1002\/path.2808","article-title":"The molecular pathology of breast cancer progression","volume":"223","author":"Bombonati A, Sgroi DC","year":"2011","unstructured":"2. Bombonati A, Sgroi DC, The molecular pathology of breast cancer progression, J Pathol, 2011;223(2):307-17","journal-title":"J Pathol"},{"issue":"18","key":"ref3","doi-asserted-by":"publisher","first-page":"7564","DOI":"10.1073\/pnas.0702507104","article-title":"Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity","volume":"104","author":"Saal LH, Johansson P, Holm K, Gruvberger-Saal SK, She QB, Maurer M","year":"2007","unstructured":"3. Saal LH, Johansson P, Holm K, Gruvberger-Saal SK, She QB, Maurer M, Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity, Proc Natl Acad Sci U S A, 2007;104(18):7564-9","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"7418","key":"ref4","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1038\/nature11412","article-title":"Comprehensive molecular portraits of human breast tumours","volume":"490","author":"Cancer Genome Atlas Network","year":"2012","unstructured":"4. Cancer Genome Atlas Network, Comprehensive molecular portraits of human breast tumours, Nature, 2012;490(7418):61-70","journal-title":"Nature"},{"issue":"11","key":"ref5","doi-asserted-by":"publisher","first-page":"1148","DOI":"10.1056\/NEJMra072067","article-title":"Epigenetics in cancer","volume":"358","author":"Esteller M","year":"2008","unstructured":"5. Esteller M, Epigenetics in cancer, N Engl J Med, 2008;358(11):1148-59","journal-title":"N Engl J Med"},{"issue":"2","key":"ref6","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1002\/path.1691","article-title":"Molecular evolution of breast cancer","volume":"205","author":"Simpson PT, Reis-Filho JS, Gale T, Lakhani SR","year":"2005","unstructured":"6. Simpson PT, Reis-Filho JS, Gale T, Lakhani SR, Molecular evolution of breast cancer, J Pathol, 2005;205(2):248-54","journal-title":"J Pathol"},{"issue":"10","key":"ref7","doi-asserted-by":"publisher","first-page":"3786","DOI":"10.1172\/JCI60534","article-title":"Heterogeneity in breast cancer","volume":"121","author":"Polyak K","year":"2011","unstructured":"7. Polyak K, Heterogeneity in breast cancer, J Clin Invest, 2011;121(10):3786-8","journal-title":"J Clin Invest"},{"issue":"11","key":"ref8","doi-asserted-by":"publisher","first-page":"a003244","DOI":"10.1101\/cshperspect.a003244","article-title":"The role of the microenvironment in mammary gland development and cancer","volume":"2","author":"Polyak K, Kalluri R","year":"2010","unstructured":"8. Polyak K, Kalluri R, The role of the microenvironment in mammary gland development and cancer, Cold Spring Harb Perspect Biol, 2010;2(11):a003244","journal-title":"Cold Spring Harb Perspect Biol"},{"issue":"6","key":"ref9","doi-asserted-by":"publisher","first-page":"CD001877","DOI":"10.1002\/14651858.CD001877.pub5","article-title":"Screening for breast cancer with mammography","volume":"2013","author":"G\u00f8tzsche PC, J\u00f8rgensen KJ","year":"2013","unstructured":"9. G\u00f8tzsche PC, J\u00f8rgensen KJ, Screening for breast cancer with mammography, Cochrane Database Syst Rev, 2013;2013(6):CD001877","journal-title":"Cochrane Database Syst Rev"},{"issue":"9","key":"ref10","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1093\/jnci\/djq099","article-title":"Overdiagnosis in cancer","volume":"102","author":"Welch HG, Black WC","year":"2010","unstructured":"10. Welch HG, Black WC, Overdiagnosis in cancer, J Natl Cancer Inst, 2010;102(9):605-13","journal-title":"J Natl Cancer Inst"},{"issue":"1","key":"ref11","doi-asserted-by":"publisher","first-page":"14301","DOI":"10.1118\/1.4770279","article-title":"A review of breast tomosynthesis Part I The image acquisition process","volume":"40","author":"Sechopoulos I","year":"2013","unstructured":"11. Sechopoulos I, A review of breast tomosynthesis Part I The image acquisition process, Med Phys, 2013;40(1):14301","journal-title":"Med Phys"},{"issue":"5","key":"ref12","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1186\/s13058-014-0435-5","article-title":"miR-638 mediated regulation of BRCA1 affects DNA repair and sensitivity to UV and cisplatin in triple-negative breast cancer","volume":"16","author":"Tan X, Peng J, Fu Y, An S, Rezaei K, Tabbara S","year":"2014","unstructured":"12. Tan X, Peng J, Fu Y, An S, Rezaei K, Tabbara S, miR-638 mediated regulation of BRCA1 affects DNA repair and sensitivity to UV and cisplatin in triple-negative breast cancer, Breast Cancer Res, 2014;16(5):435","journal-title":"Breast Cancer Res"},{"issue":"2","key":"ref13","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1016\/j.cell.2009.01.002","article-title":"MicroRNAs: target recognition and regulatory functions","volume":"136","author":"Bartel DP","year":"2009","unstructured":"13. Bartel DP, MicroRNAs: target recognition and regulatory functions, Cell, 2009;136(2):215-33","journal-title":"Cell"},{"issue":"1","key":"ref14","doi-asserted-by":"publisher","first-page":"315","DOI":"10.3892\/mmr.2014.2222","article-title":"microRNA-200c downregulates XIAP expression to suppress proliferation and promote apoptosis of triple-negative breast cancer cells","volume":"10","author":"Ren Y, Han X, Yu K, Sun S, Zhen L, Li Z","year":"2014","unstructured":"14. Ren Y, Han X, Yu K, Sun S, Zhen L, Li Z, microRNA-200c downregulates XIAP expression to suppress proliferation and promote apoptosis of triple-negative breast cancer cells, Mol Med Rep, 2014;10(1):315-21","journal-title":"Mol Med Rep"},{"issue":"7","key":"ref15","doi-asserted-by":"publisher","first-page":"1602","DOI":"10.1002\/ijc.27799","article-title":"Circulating microRNAs in plasma as early detection markers for breast cancer","volume":"132","author":"Cuk K, Zucknick M, Heil J, Madhavan D, Schott S, Turchinovich A","year":"2013","unstructured":"15. Cuk K, Zucknick M, Heil J, Madhavan D, Schott S, Turchinovich A, Circulating microRNAs in plasma as early detection markers for breast cancer, Int J Cancer, 2013;132(7):1602-12","journal-title":"Int J Cancer"},{"issue":"3","key":"ref16","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1007\/s12094-013-1132-z","article-title":"MicroRNA-21 in breast cancer: diagnostic and prognostic potential","volume":"16","author":"Chen J, Wang X","year":"2014","unstructured":"16. Chen J, Wang X, MicroRNA-21 in breast cancer: diagnostic and prognostic potential, Clin Transl Oncol, 2014;16(3):225-33","journal-title":"Clin Transl Oncol"},{"issue":"5","key":"ref17","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1080\/08830180903093796","article-title":"miR-155: on the crosstalk between inflammation and cancer","volume":"28","author":"Tili E, Croce CM, Michaille JJ","year":"2009","unstructured":"17. Tili E, Croce CM, Michaille JJ, miR-155: on the crosstalk between inflammation and cancer, Int Rev Immunol, 2009;28(5):264-84","journal-title":"Int Rev Immunol"},{"issue":"5","key":"ref18","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1038\/ncb1722","article-title":"The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1","volume":"10","author":"Gregory PA, Bert AG, Paterson EL, Barry SC, Tsykin A, Farshid G","year":"2008","unstructured":"18. Gregory PA, Bert AG, Paterson EL, Barry SC, Tsykin A, Farshid G, The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1, Nat Cell Biol, 2008;10(5):593-601","journal-title":"Nat Cell Biol"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"448","DOI":"10.1186\/1471-2407-14-448","article-title":"Oncogenic microRNAs: miR-155, miR-19a, miR-181b, and miR-24 enable monitoring of early breast cancer in serum","volume":"14","author":"Sochor M, Basova P, Pesta M, Dusilkova N, Bartos J, Burda P","year":"2014","unstructured":"19. Sochor M, Basova P, Pesta M, Dusilkova N, Bartos J, Burda P, Oncogenic microRNAs: miR-155, miR-19a, miR-181b, and miR-24 enable monitoring of early breast cancer in serum, BMC Cancer, 2014;14448","journal-title":"BMC Cancer"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1186\/s13058-015-0526-y","article-title":"Dysregulation of microRNAs in breast cancer and their potential role as prognostic and predictive biomarkers in patient management","volume":"17","author":"van Schooneveld E, Wildiers H, Vergote I, Vermeulen PB, Dirix LY, Van Laere SJ","year":"2015","unstructured":"20. van Schooneveld E, Wildiers H, Vergote I, Vermeulen PB, Dirix LY, Van Laere SJ, Dysregulation of microRNAs in breast cancer and their potential role as prognostic and predictive biomarkers in patient management, Breast Cancer Res, 2015;1721","journal-title":"Breast Cancer Res"},{"issue":"1","key":"ref21","doi-asserted-by":"publisher","first-page":"e53141","DOI":"10.1371\/journal.pone.0053141","article-title":"Circulating microRNAs as specific biomarkers for breast cancer detection","volume":"8","author":"Ng EK, Li R, Shin VY, Jin HC, Leung CP, Ma ES","year":"2013","unstructured":"21. Ng EK, Li R, Shin VY, Jin HC, Leung CP, Ma ES, Circulating microRNAs as specific biomarkers for breast cancer detection, PLoS One, 2013;8(1):e53141","journal-title":"PLoS One"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"149","DOI":"10.3389\/fgene.2014.00149","article-title":"Different miRNA expression profiles between human breast cancer tumors and serum","volume":"5","author":"Zhu J, Zheng Z, Wang J, Sun J, Wang P, Cheng X","year":"2014","unstructured":"22. Zhu J, Zheng Z, Wang J, Sun J, Wang P, Cheng X, Different miRNA expression profiles between human breast cancer tumors and serum, Front Genet, 2014;5149","journal-title":"Front Genet"},{"issue":"3","key":"ref23","doi-asserted-by":"publisher","first-page":"1303","DOI":"10.1074\/jbc.M113.502278","article-title":"Characterization of a stem-like subpopulation in basal-like ductal carcinoma in situ (DCIS) lesions","volume":"289","author":"Li Q, Eades G, Yao Y, Zhang Y, Zhou Q","year":"2014","unstructured":"23. Li Q, Eades G, Yao Y, Zhang Y, Zhou Q, Characterization of a stem-like subpopulation in basal-like ductal carcinoma in situ (DCIS) lesions, J Biol Chem, 2014;289(3):1303-12","journal-title":"J Biol Chem"},{"issue":"2","key":"ref24","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1038\/nprot.2007.528","article-title":"MicroRNA detection by northern blotting using locked nucleic acid probes","volume":"3","author":"V\u00e1rallyay E, Burgy\u00e1n J, Havelda Z","year":"2008","unstructured":"24. V\u00e1rallyay E, Burgy\u00e1n J, Havelda Z, MicroRNA detection by northern blotting using locked nucleic acid probes, Nat Protoc, 2008;3(2):190-6","journal-title":"Nat Protoc"},{"issue":"6","key":"ref25","doi-asserted-by":"publisher","first-page":"1077","DOI":"10.1038\/nprot.2008.67","article-title":"Improved northern blot method for enhanced detection of small RNA","volume":"3","author":"Pall GS, Hamilton AJ","year":"2008","unstructured":"25. Pall GS, Hamilton AJ, Improved northern blot method for enhanced detection of small RNA, Nat Protoc, 2008;3(6):1077-84","journal-title":"Nat Protoc"},{"issue":"1","key":"ref26","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1038\/nmeth0106-12","article-title":"microRNA detection comes of age","volume":"3","author":"Hammond SM","year":"2006","unstructured":"26. Hammond SM, microRNA detection comes of age, Nat Methods, 2006;3(1):12-3","journal-title":"Nat Methods"},{"issue":"26","key":"ref27","doi-asserted-by":"publisher","first-page":"9740","DOI":"10.1073\/pnas.0403293101","article-title":"An oligonucleotide microchip for genome-wide microRNA profiling in human and mouse tissues","volume":"101","author":"Liu CG, Calin GA, Meloon B, Gamliel N, Sevignani C, Ferracin M","year":"2004","unstructured":"27. Liu CG, Calin GA, Meloon B, Gamliel N, Sevignani C, Ferracin M, An oligonucleotide microchip for genome-wide microRNA profiling in human and mouse tissues, Proc Natl Acad Sci U S A, 2004;101(26):9740-4","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"20","key":"ref28","doi-asserted-by":"publisher","first-page":"e179","DOI":"10.1093\/nar\/gni178","article-title":"Real-time quantification of microRNAs by stem-loop RT-PCR","volume":"33","author":"Chen C, Ridzon DA, Broomer AJ, Zhou Z, Lee DH, Nguyen JT","year":"2005","unstructured":"28. Chen C, Ridzon DA, Broomer AJ, Zhou Z, Lee DH, Nguyen JT, Real-time quantification of microRNAs by stem-loop RT-PCR, Nucleic Acids Res, 2005;33(20):e179","journal-title":"Nucleic Acids Res"},{"issue":"4","key":"ref29","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1038\/nbt1394","article-title":"Discovering microRNAs from deep sequencing data using miRDeep","volume":"26","author":"Friedl\u00e4nder MR, Chen W, Adamidi C, Maaskola J, Einspanier R, Knespel S, Rajewsky N","year":"2008","unstructured":"29. Friedl\u00e4nder MR, Chen W, Adamidi C, Maaskola J, Einspanier R, Knespel S, Rajewsky N, Discovering microRNAs from deep sequencing data using miRDeep, Nat Biotechnol, 2008;26(4):407-15","journal-title":"Nat Biotechnol"},{"issue":"7043","key":"ref30","doi-asserted-by":"publisher","first-page":"834","DOI":"10.1038\/nature03702","article-title":"MicroRNA expression profiles classify human cancers","volume":"435","author":"Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, Peck D","year":"2005","unstructured":"30. Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, Peck D, MicroRNA expression profiles classify human cancers, Nature, 2005;435(7043):834-8","journal-title":"Nature"},{"issue":"4","key":"ref31","doi-asserted-by":"publisher","first-page":"1117","DOI":"10.1007\/s00216-008-2570-2","article-title":"MicroRNA detection by microarray","volume":"394","author":"Li W, Ruan K","year":"2009","unstructured":"31. Li W, Ruan K, MicroRNA detection by microarray, Anal Bioanal Chem, 2009;394(4):1117-24","journal-title":"Anal Bioanal Chem"},{"issue":"7043","key":"ref32","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1038\/nature03702","article-title":"MicroRNA expression profiles classify human cancers","volume":"435","author":"Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, Peck D","year":"2005","unstructured":"32. Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, Peck D, MicroRNA expression profiles classify human cancers, Nature, 2005;435(7043):834-838","journal-title":"Nature"},{"issue":"1","key":"ref33","doi-asserted-by":"publisher","first-page":"4504","DOI":"10.1038\/s41598-021-83888-5","article-title":"A novel approach for microRNA in situ hybridization using locked nucleic acid probes","volume":"11","author":"Paulsen IW, Bzorek M, Olsen J, Grum-Schwensen B, Troelsen JT, Pedersen OB","year":"2021","unstructured":"33. Paulsen IW, Bzorek M, Olsen J, Grum-Schwensen B, Troelsen JT, Pedersen OB, A novel approach for microRNA in situ hybridization using locked nucleic acid probes, Sci Rep, 2021;11(1):4504","journal-title":"Sci Rep"},{"issue":"1","key":"ref34","doi-asserted-by":"publisher","first-page":"17981","DOI":"10.1038\/s41598-018-36321-3","article-title":"Plasma miR-21, miR-155, miR-10b, and Let-7a as the potential biomarkers for the monitoring of breast cancer patients","volume":"8","author":"Khalighfard S, Alizadeh AM, Irani S, Omranipour R","year":"2018","unstructured":"34. Khalighfard S, Alizadeh AM, Irani S, Omranipour R, Plasma miR-21, miR-155, miR-10b, and Let-7a as the potential biomarkers for the monitoring of breast cancer patients, Sci Rep, 2018;8(1):17981","journal-title":"Sci Rep"},{"issue":"4","key":"ref35","doi-asserted-by":"publisher","first-page":"e34210","DOI":"10.1371\/journal.pone.0034210","article-title":"Circulating MiR-125b as a marker predicting chemoresistance in breast cancer","volume":"7","author":"Wang H, Tan G, Dong L, Cheng L, Li K, Wang Z","year":"2012","unstructured":"35. Wang H, Tan G, Dong L, Cheng L, Li K, Wang Z, Circulating MiR-125b as a marker predicting chemoresistance in breast cancer, PLoS One, 2012;7(4):e34210","journal-title":"PLoS One"},{"issue":"4","key":"ref36","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1038\/nbt.1618","article-title":"Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model","volume":"28","author":"Ma L, Reinhardt F, Pan E, Soutschek J, Bhat B, Marcusson EG","year":"2010","unstructured":"36. Ma L, Reinhardt F, Pan E, Soutschek J, Bhat B, Marcusson EG, Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model, Nat Biotechnol, 2010;28(4):341-7","journal-title":"Nat Biotechnol"},{"issue":"5","key":"ref37","doi-asserted-by":"publisher","first-page":"874","DOI":"10.1016\/j.molonc.2014.03.002","article-title":"Novel circulating microRNA signature as a potential non-invasive multi-marker test in ER-positive early-stage breast cancer: a case control study","volume":"8","author":"Kodahl AR, Lyng MB, Binder H, Cold S, Gravgaard K, Knoop AS","year":"2014","unstructured":"37. Kodahl AR, Lyng MB, Binder H, Cold S, Gravgaard K, Knoop AS, Novel circulating microRNA signature as a potential non-invasive multi-marker test in ER-positive early-stage breast cancer: a case control study, Mol Oncol, 2014;8(5):874-83","journal-title":"Mol Oncol"},{"issue":"5","key":"ref38","doi-asserted-by":"publisher","first-page":"6282","DOI":"10.3390\/molecules19056282","article-title":"Increased circulating microRNA-155 as a potential biomarker for breast cancer screening: a meta-analysis","volume":"19","author":"Wang F, Hou J, Jin W, Li J, Yue Y, Jin H, Wang X","year":"2014","unstructured":"38. Wang F, Hou J, Jin W, Li J, Yue Y, Jin H, Wang X, Increased circulating microRNA-155 as a potential biomarker for breast cancer screening: a meta-analysis, Molecules, 2014;19(5):6282-93","journal-title":"Molecules"},{"issue":"16","key":"ref39","doi-asserted-by":"publisher","first-page":"4477","DOI":"10.1158\/1078-0432.CCR-12-3401","article-title":"Identification of circulating microRNA signatures for breast cancer detection","volume":"19","author":"Chan M, Liaw CS, Ji SM, Tan HH, Wong CY, Thike AA","year":"2013","unstructured":"39. Chan M, Liaw CS, Ji SM, Tan HH, Wong CY, Thike AA, Identification of circulating microRNA signatures for breast cancer detection, Clin Cancer Res, 2013;19(16):4477-87","journal-title":"Clin Cancer Res"},{"issue":"7","key":"ref40","doi-asserted-by":"publisher","first-page":"1602","DOI":"10.1002\/ijc.27799","article-title":"Circulating microRNAs in plasma as early detection markers for breast cancer","volume":"132","author":"Cuk K, Zucknick M, Heil J, Madhavan D, Schott S, Turchinovich A","year":"2013","unstructured":"40. Cuk K, Zucknick M, Heil J, Madhavan D, Schott S, Turchinovich A, Circulating microRNAs in plasma as early detection markers for breast cancer, Int J Cancer, 2013;132(7):1602-12","journal-title":"Int J Cancer"},{"issue":"1","key":"ref41","doi-asserted-by":"publisher","first-page":"e53141","DOI":"10.1371\/journal.pone.0053141","article-title":"Circulating microRNAs as specific biomarkers for breast cancer detection","volume":"8","author":"Ng EK, Li R, Shin VY, Jin HC, Leung CP, Ma ES","year":"2013","unstructured":"41. Ng EK, Li R, Shin VY, Jin HC, Leung CP, Ma ES, Circulating microRNAs as specific biomarkers for breast cancer detection, PLoS One, 2013;8(1):e53141","journal-title":"PLoS One"},{"issue":"3","key":"ref42","doi-asserted-by":"publisher","first-page":"R42","DOI":"10.1186\/bcr3428","article-title":"Serum microRNA expression as an early marker for breast cancer risk in prospectively collected samples from the Sister Study cohort","volume":"15","author":"Godfrey AC, Xu Z, Weinberg CR, Getts RC, Wade PA, DeRoo LA","year":"2013","unstructured":"42. Godfrey AC, Xu Z, Weinberg CR, Getts RC, Wade PA, DeRoo LA, Serum microRNA expression as an early marker for breast cancer risk in prospectively collected samples from the Sister Study cohort, Breast Cancer Res, 2013;15(3):R42","journal-title":"Breast Cancer Res"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"950201","DOI":"10.1155\/2010\/950201","article-title":"MicroRNAs as Novel Biomarkers for Breast Cancer","volume":"2009","author":"Heneghan HM, Miller N, Lowery AJ, Sweeney KJ, Kerin MJ","year":"2009","unstructured":"43. Heneghan HM, Miller N, Lowery AJ, Sweeney KJ, Kerin MJ, MicroRNAs as Novel Biomarkers for Breast Cancer, J Oncol, 2009;2009950201","journal-title":"J Oncol"},{"issue":"16","key":"ref44","doi-asserted-by":"publisher","first-page":"7065","DOI":"10.1158\/0008-5472.CAN-05-1783","article-title":"MicroRNA gene expression deregulation in human breast cancer","volume":"65","author":"Iorio MV, Ferracin M, Liu CG, Veronese A, Spizzo R, Sabbioni S","year":"2005","unstructured":"44. Iorio MV, Ferracin M, Liu CG, Veronese A, Spizzo R, Sabbioni S, MicroRNA gene expression deregulation in human breast cancer, Cancer Res, 2005;65(16):7065-70","journal-title":"Cancer Res"},{"issue":"10","key":"ref45","doi-asserted-by":"publisher","first-page":"1985","DOI":"10.1038\/bjc.2014.489","article-title":"Serum microRNA panel as biomarkers for early diagnosis of colorectal adenocarcinoma","volume":"111","author":"Zheng G, Du L, Yang X, Zhang X, Wang L, Yang Y","year":"2014","unstructured":"45. Zheng G, Du L, Yang X, Zhang X, Wang L, Yang Y, Serum microRNA panel as biomarkers for early diagnosis of colorectal adenocarcinoma, Br J Cancer, 2014;111(10):1985-92","journal-title":"Br J Cancer"},{"issue":"3","key":"ref46","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1097\/SLA.0b013e3181cc939f","article-title":"Circulating microRNAs as novel minimally invasive biomarkers for breast cancer","volume":"251","author":"Heneghan HM, Miller N, Lowery AJ, Sweeney KJ, Newell J, Kerin MJ","year":"2010","unstructured":"46. Heneghan HM, Miller N, Lowery AJ, Sweeney KJ, Newell J, Kerin MJ, Circulating microRNAs as novel minimally invasive biomarkers for breast cancer, Ann Surg, 2010;251(3):499-505","journal-title":"Ann Surg"}],"container-title":["Journal of Medicine and Life"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/medandlife.org\/all-issues\/2024\/issue-6-2024\/review-issue-6-2024\/mirnas-as-potential-biomarkers-in-early-breast-cancer-detection-a-systematic-review\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,29]],"date-time":"2024-10-29T11:11:05Z","timestamp":1730200265000},"score":1,"resource":{"primary":{"URL":"https:\/\/medandlife.org\/all-issues\/2024\/issue-6-2024\/review-issue-6-2024\/mirnas-as-potential-biomarkers-in-early-breast-cancer-detection-a-systematic-review\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6]]},"references-count":46,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["JMedLife-17-549"],"URL":"https:\/\/doi.org\/10.25122\/jml-2024-0322","relation":{},"ISSN":["1844-3117"],"issn-type":[{"value":"1844-3117","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6]]}}}