{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T09:09:46Z","timestamp":1788772186375,"version":"build-2803163510"},"reference-count":48,"publisher":"S.C. JURNALUL PENTRU MEDICINA SI VIATA S.R.L","issue":"6","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.25122\/jml-2026-0019","type":"journal-article","created":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T08:34:27Z","timestamp":1788770067000},"page":"426-432","source":"Crossref","is-referenced-by-count":0,"title":["Autoimmune thyroiditis in pregnancy: epidemiology, clinical impact, and contemporary management challenges"],"prefix":"10.25122","volume":"19","author":[{"given":"Octavian","family":"Munteanu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Carol Davila University of Medicine and Pharmacy, Bucharest, Romania","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of Obstetrics and Gynecology, University Emergency Hospital Bucharest, Bucharest, Romania","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alina","family":"Potorac","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Doctoral School, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Carol Davila University of Medicine and Pharmacy, Bucharest, Romania","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandru","family":"Baros","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Carol Davila University of Medicine and Pharmacy, Bucharest, Romania","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of Obstetrics and Gynecology, University Emergency Hospital Bucharest, Bucharest, Romania","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena Evelina","family":"Stoica","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Carol Davila University of Medicine and Pharmacy, Bucharest, Romania","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of Obstetrics and Gynecology, University Emergency Hospital Bucharest, Bucharest, Romania","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica Mihaela","family":"Cirstoiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Carol Davila University of Medicine and Pharmacy, Bucharest, Romania","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of Obstetrics and Gynecology, University Emergency Hospital Bucharest, Bucharest, Romania","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10755","reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"8520","DOI":"10.3390\/jcm14238520","article-title":"Effect of autoimmune thyroid disease on pregnancy outcomes: a systematic review and meta-analysis","volume":"14","author":"Sayed AA, Abdulaal MM, Emam EM, Daftardar LM, Kurdi RE, Alahmadi YB","year":"2025","unstructured":"1. Sayed AA, Abdulaal MM, Emam EM, Daftardar LM, Kurdi RE, Alahmadi YB, Effect of autoimmune thyroid disease on pregnancy outcomes: a systematic review and meta-analysis, J Clin Med, 2025;148520","journal-title":"J Clin Med"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"190","DOI":"10.3390\/jcm14010190","article-title":"Autoimmune thyroid disease and pregnancy: the interaction between genetics, epigenetics and environmental factors","volume":"14","author":"Bogovi\u0107 Crn\u010di\u0107 T, \u0106urko-Cofek B, Bati\u010di\u0107 L, Girotto N, Toma\u0161 MI, Kr\u0161ek A","year":"2024","unstructured":"2. Bogovi\u0107 Crn\u010di\u0107 T, \u0106urko-Cofek B, Bati\u010di\u0107 L, Girotto N, Toma\u0161 MI, Kr\u0161ek A, Autoimmune thyroid disease and pregnancy: the interaction between genetics, epigenetics and environmental factors, J Clin Med, 2024;14190","journal-title":"J Clin Med"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"50","DOI":"10.3389\/fendo.2017.00050","article-title":"Environmental issues in thyroid diseases","volume":"8","author":"Ferrari SM, Fallahi P, Antonelli A, Benvenga S","year":"2017","unstructured":"3. Ferrari SM, Fallahi P, Antonelli A, Benvenga S, Environmental issues in thyroid diseases, Front Endocrinol (Lausanne), 2017;850","journal-title":"Front Endocrinol (Lausanne)"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"249","DOI":"10.30699\/jogcr.9.3.249","article-title":"Comparison of pregnancy outcomes in pregnant women with positive and negative anti-thyroid peroxidase antibody","volume":"9","author":"Shahbazian N, Zargar M, Barati M, Saadati N, Direkvand E","year":"2024","unstructured":"4. Shahbazian N, Zargar M, Barati M, Saadati N, Direkvand E, Comparison of pregnancy outcomes in pregnant women with positive and negative anti-thyroid peroxidase antibody, J Obstet Gynecol Cancer Res, 2024;9249-256","journal-title":"J Obstet Gynecol Cancer Res"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"56","DOI":"10.3390\/endocrines6040056","article-title":"The impact of chronic autoimmune thyroiditis during pregnancy on maternal and fetal outcomes","volume":"6","author":"Scrinic O, Circo E, Musledin S","year":"2025","unstructured":"5. Scrinic O, Circo E, Musledin S, The impact of chronic autoimmune thyroiditis during pregnancy on maternal and fetal outcomes, Endocrines, 2025;656","journal-title":"Endocrines"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"8520","DOI":"10.3390\/jcm14238520","article-title":"Effect of autoimmune thyroid disease on pregnancy outcomes: a systematic review and meta-analysis","volume":"14","author":"Sayed AA, Abdulaal MM, Emam EM, Daftardar LM, Kurdi RE, Alahmadi YB","year":"2025","unstructured":"6. Sayed AA, Abdulaal MM, Emam EM, Daftardar LM, Kurdi RE, Alahmadi YB, Effect of autoimmune thyroid disease on pregnancy outcomes: a systematic review and meta-analysis, J Clin Med, 2025;148520","journal-title":"J Clin Med"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"37060","DOI":"10.31083\/CEOG37060","article-title":"The role of thyroid autoimmunity in assisted reproductive techniques outcomes: an updated comprehensive meta-analysis","volume":"52","author":"Ghaderkhanzadeh H, Asadi J, Hemmati Z, Saed L, Nouri E, Moradi Y","year":"2025","unstructured":"7. Ghaderkhanzadeh H, Asadi J, Hemmati Z, Saed L, Nouri E, Moradi Y, The role of thyroid autoimmunity in assisted reproductive techniques outcomes: an updated comprehensive meta-analysis, Clin Exp Obstet Gynecol, 2025;5237060","journal-title":"Clin Exp Obstet Gynecol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"1711369","DOI":"10.3389\/fendo.2025.1711369","article-title":"Association of thyroid autoimmunity and pregnancy outcomes in unexplained recurrent pregnancy loss women: a prospective cohort study","volume":"16","author":"Wang R, Liu L, Zhang W, Zhang J, Wang K, Wang F","year":"2025","unstructured":"8. Wang R, Liu L, Zhang W, Zhang J, Wang K, Wang F, Association of thyroid autoimmunity and pregnancy outcomes in unexplained recurrent pregnancy loss women: a prospective cohort study, Front Endocrinol (Lausanne), 2025;161711369","journal-title":"Front Endocrinol (Lausanne)"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"18","DOI":"10.21037\/aot.2018.07.03","article-title":"Autoimmune thyroid diseases and pregnancy","volume":"3","author":"Moleti M, Sturniolo G, Di Mauro M, Russo M, Vermiglio F","year":"2018","unstructured":"9. Moleti M, Sturniolo G, Di Mauro M, Russo M, Vermiglio F, Autoimmune thyroid diseases and pregnancy, Ann Thyroid, 2018;318","journal-title":"Ann Thyroid"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1016\/S2213-8587(17)30402-3","article-title":"Autoimmune thyroid disease during pregnancy","volume":"6","author":"De Leo S, Pearce EN","year":"2018","unstructured":"10. De Leo S, Pearce EN, Autoimmune thyroid disease during pregnancy, Lancet Diabetes Endocrinol, 2018;6575-586","journal-title":"Lancet Diabetes Endocrinol"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"630","DOI":"10.1186\/s12905-024-03473-6","article-title":"Prevalence of thyroid autoantibody positivity in women with infertility: a systematic review and meta-analysis","volume":"24","author":"Huang Y, Xie B, Li J, Hang F, Hu Q, Jin Y","year":"2024","unstructured":"11. Huang Y, Xie B, Li J, Hang F, Hu Q, Jin Y, Prevalence of thyroid autoantibody positivity in women with infertility: a systematic review and meta-analysis, BMC Womens Health, 2024;24630","journal-title":"BMC Womens Health"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"3720","DOI":"10.3390\/nu16213720","article-title":"Iodine nutritional status and thyroid autoimmunity in Chinese children and adolescents aged 6-17 years","volume":"16","author":"Li X, Zhang J, Ding H, Tu P, Wu L, Xing M","year":"2024","unstructured":"12. Li X, Zhang J, Ding H, Tu P, Wu L, Xing M, Iodine nutritional status and thyroid autoimmunity in Chinese children and adolescents aged 6-17 years, Nutrients, 2024;163720","journal-title":"Nutrients"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1530\/ETJ-23-0230","article-title":"The Danish investigation on iodine intake and thyroid disease (DanThyr): history and implications","volume":"13","author":"Tang M\u00f8llehave L, Knudsen N, Linneberg A, B\u00fclow Pedersen I, Ravn-Haren G, Madsen AL","year":"2024","unstructured":"13. Tang M\u00f8llehave L, Knudsen N, Linneberg A, B\u00fclow Pedersen I, Ravn-Haren G, Madsen AL, The Danish investigation on iodine intake and thyroid disease (DanThyr): history and implications, Eur Thyroid J, 2024;13","journal-title":"Eur Thyroid J"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"526","DOI":"10.1038\/nrendo.2010.91","article-title":"Serum TSH determinations in pregnancy: how, when and why?","volume":"6","author":"Glinoer D, Spencer CA","year":"2010","unstructured":"14. Glinoer D, Spencer CA, Serum TSH determinations in pregnancy: how, when and why?, Nat Rev Endocrinol, 2010;6526-529","journal-title":"Nat Rev Endocrinol"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"1756216","DOI":"10.3389\/fendo.2025.1756216","article-title":"Correction: Association of thyroid autoimmunity and pregnancy outcomes in unexplained recurrent pregnancy loss women: a prospective cohort study","volume":"16","author":"Wang R, Liu L, Zhang W, Zhang J, Wang K, Wang F","year":"2025","unstructured":"15. Wang R, Liu L, Zhang W, Zhang J, Wang K, Wang F, Correction: Association of thyroid autoimmunity and pregnancy outcomes in unexplained recurrent pregnancy loss women: a prospective cohort study, Front Endocrinol (Lausanne), 2025;161756216","journal-title":"Front Endocrinol (Lausanne)"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"646","DOI":"10.1089\/thy.2023.0646","article-title":"Risk factors for thyroid dysfunction in pregnancy: an individual participant data meta-analysis","volume":"34","author":"Osinga JAJ, Liu Y, M\u00e4nnist\u00f6 T, Vafeiadi M, Tao FB, Vaidya B","year":"2024","unstructured":"16. Osinga JAJ, Liu Y, M\u00e4nnist\u00f6 T, Vafeiadi M, Tao FB, Vaidya B, Risk factors for thyroid dysfunction in pregnancy: an individual participant data meta-analysis, Thyroid, 2024;34646-658","journal-title":"Thyroid"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/S2213-8587(15)00327-7","article-title":"Association of maternal thyroid function during early pregnancy with offspring IQ and brain morphology in childhood: a population-based prospective cohort study","volume":"4","author":"Korevaar TIM, Muetzel R, Medici M, Chaker L, Jaddoe VWV, De Rijke YB","year":"2016","unstructured":"17. Korevaar TIM, Muetzel R, Medici M, Chaker L, Jaddoe VWV, De Rijke YB, Association of maternal thyroid function during early pregnancy with offspring IQ and brain morphology in childhood: a population-based prospective cohort study, Lancet Diabetes Endocrinol, 2016;435-43","journal-title":"Lancet Diabetes Endocrinol"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"1400","DOI":"10.18203\/2320-1770.ijrcog20181324","article-title":"Thyroid peroxidase antibody positivity among euthyroid pregnant women and its association with foeto-maternal outcome","volume":"7","author":"Gulati K, Sharma M, Bharti R, Biswas K, Batra A, Aggarwal A","year":"2018","unstructured":"18. Gulati K, Sharma M, Bharti R, Biswas K, Batra A, Aggarwal A, Thyroid peroxidase antibody positivity among euthyroid pregnant women and its association with foeto-maternal outcome, Int J Reprod Contracept Obstet Gynecol, 2018;71400","journal-title":"Int J Reprod Contracept Obstet Gynecol"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1016\/S2213-8587(14)70225-6","article-title":"Iodine deficiency and thyroid disorders","volume":"3","author":"Zimmermann MB, Boelaert K","year":"2015","unstructured":"19. Zimmermann MB, Boelaert K, Iodine deficiency and thyroid disorders, Lancet Diabetes Endocrinol, 2015;3286-295","journal-title":"Lancet Diabetes Endocrinol"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"1081851","DOI":"10.3389\/fendo.2023.1081851","article-title":"Thyroid autoimmunity and adverse pregnancy outcomes: a multiple center retrospective study","volume":"14","author":"Xu Y, Chen H, Ren M, Gao Y, Sun K, Wu H","year":"2023","unstructured":"20. Xu Y, Chen H, Ren M, Gao Y, Sun K, Wu H, Thyroid autoimmunity and adverse pregnancy outcomes: a multiple center retrospective study, Front Endocrinol (Lausanne), 2023;141081851","journal-title":"Front Endocrinol (Lausanne)"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1186\/s40748-025-00208-9","article-title":"Overview of thyroid disorders in pregnancy","volume":"11","author":"Puthiyachirakal MA, Hopkins M, AlNatsheh T, Das A","year":"2025","unstructured":"21. Puthiyachirakal MA, Hopkins M, AlNatsheh T, Das A, Overview of thyroid disorders in pregnancy, Matern Health Neonatol Perinatol, 2025;119","journal-title":"Matern Health Neonatol Perinatol"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1186\/s12937-022-00760-6","article-title":"Iodine nutrition status and thyroid autoimmunity during pregnancy: a cross-sectional study of 4635 pregnant women","volume":"21","author":"Chen X, Wu C, Wang Z, Wu C, Guo Y, Zhu X","year":"2022","unstructured":"22. Chen X, Wu C, Wang Z, Wu C, Guo Y, Zhu X, Iodine nutrition status and thyroid autoimmunity during pregnancy: a cross-sectional study of 4635 pregnant women, Nutr J, 2022;217","journal-title":"Nutr J"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"632","DOI":"10.1001\/jama.2019.10931","article-title":"Association of thyroid function test abnormalities and thyroid autoimmunity with preterm birth: a systematic review and meta-analysis","volume":"322","author":"Korevaar TIM, Derakhshan A, Taylor PN, Meima M, Chen L, Bliddal S","year":"2019","unstructured":"23. Korevaar TIM, Derakhshan A, Taylor PN, Meima M, Chen L, Bliddal S, Association of thyroid function test abnormalities and thyroid autoimmunity with preterm birth: a systematic review and meta-analysis, JAMA, 2019;322632-641","journal-title":"JAMA"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d2616","article-title":"Association between thyroid autoantibodies and miscarriage and preterm birth: meta-analysis of evidence","volume":"342","author":"Thangaratinam S, Tan A, Knox E, Kilby MD, Franklyn J, Coomarasamy A","year":"2011","unstructured":"24. Thangaratinam S, Tan A, Knox E, Kilby MD, Franklyn J, Coomarasamy A, Association between thyroid autoantibodies and miscarriage and preterm birth: meta-analysis of evidence, BMJ, 2011;342","journal-title":"BMJ"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-025-08294-5","article-title":"Maternal endocrine and metabolic health and outcomes (MEMO): a prospective cohort study of gestational diabetes mellitus and subclinical hypothyroidism in China","author":"Zeng Y, Yu J, Ren Y, Ren J, Chen H, Zhang Q","year":"2025","unstructured":"25. Zeng Y, Yu J, Ren Y, Ren J, Chen H, Zhang Q, Maternal endocrine and metabolic health and outcomes (MEMO): a prospective cohort study of gestational diabetes mellitus and subclinical hypothyroidism in China, BMC Pregnancy Childbirth, 2025;","journal-title":"BMC Pregnancy Childbirth"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1016\/S2213-8587(22)00007-9","article-title":"Association between maternal thyroid function and risk of gestational hypertension and pre-eclampsia: a systematic review and individual-participant data meta-analysis","volume":"10","author":"Toloza FJK, Derakhshan A, M\u00e4nnist\u00f6 T, Bliddal S, Popova PV, Carty DM","year":"2022","unstructured":"26. Toloza FJK, Derakhshan A, M\u00e4nnist\u00f6 T, Bliddal S, Popova PV, Carty DM, Association between maternal thyroid function and risk of gestational hypertension and pre-eclampsia: a systematic review and individual-participant data meta-analysis, Lancet Diabetes Endocrinol, 2022;10243-252","journal-title":"Lancet Diabetes Endocrinol"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"1081851","DOI":"10.3389\/fendo.2023.1081851","article-title":"Thyroid autoimmunity and adverse pregnancy outcomes: a multiple center retrospective study","volume":"14","author":"Xu Y, Chen H, Ren M, Gao Y, Sun K, Wu H","year":"2023","unstructured":"27. Xu Y, Chen H, Ren M, Gao Y, Sun K, Wu H, Thyroid autoimmunity and adverse pregnancy outcomes: a multiple center retrospective study, Front Endocrinol (Lausanne), 2023;141081851","journal-title":"Front Endocrinol (Lausanne)"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.18088","article-title":"Management of thyroid disorders in pregnancy: Green-top Guideline No 76.","volume":"132","author":"Chan S, Marsh MS, Gilbert J, Boelaert K, Evans C, Dhillon-Smith R","year":"2025","unstructured":"28. Chan S, Marsh MS, Gilbert J, Boelaert K, Evans C, Dhillon-Smith R, Management of thyroid disorders in pregnancy: Green-top Guideline No 76., BJOG, 2025;132","journal-title":"BJOG"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-17-0598","article-title":"Identifying and treating subclinical thyroid dysfunction in pregnancy: emerging controversies","volume":"178","author":"Velasco I, Taylor P","year":"2018","unstructured":"29. Velasco I, Taylor P, Identifying and treating subclinical thyroid dysfunction in pregnancy: emerging controversies, Eur J Endocrinol, 2018;178","journal-title":"Eur J Endocrinol"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"4227","DOI":"10.1210\/jc.2010-0415","article-title":"Maternal thyroid function during early pregnancy and cognitive functioning in early childhood: the Generation R Study","volume":"95","author":"Henrichs J, Bongers-Schokking JJ, Schenk JJ, Ghassabian A, Schmidt HG, Visser TJ","year":"2010","unstructured":"30. Henrichs J, Bongers-Schokking JJ, Schenk JJ, Ghassabian A, Schmidt HG, Visser TJ, Maternal thyroid function during early pregnancy and cognitive functioning in early childhood: the Generation R Study, J Clin Endocrinol Metab, 2010;954227-4234","journal-title":"J Clin Endocrinol Metab"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1016\/j.beem.2004.03.008","article-title":"Postpartum thyroiditis","volume":"18","author":"Stagnaro-Green A","year":"2004","unstructured":"31. Stagnaro-Green A, Postpartum thyroiditis, Best Pract Res Clin Endocrinol Metab, 2004;18303-316","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1089\/thy.2016.0457","article-title":"2017 guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and the postpartum","volume":"27","author":"Alexander EK, Pearce EN, Brent GA, Brown RS, Chen H, Dosiou C","year":"2017","unstructured":"32. Alexander EK, Pearce EN, Brent GA, Brown RS, Chen H, Dosiou C, 2017 guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and the postpartum, Thyroid, 2017;27315-389","journal-title":"Thyroid"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"610","DOI":"10.1038\/nrendo.2017.93","article-title":"Thyroid disease in pregnancy: new insights in diagnosis and clinical management","volume":"13","author":"Korevaar TIM, Medici M, Visser TJ, Peeters RP","year":"2017","unstructured":"33. Korevaar TIM, Medici M, Visser TJ, Peeters RP, Thyroid disease in pregnancy: new insights in diagnosis and clinical management, Nat Rev Endocrinol, 2017;13610-622","journal-title":"Nat Rev Endocrinol"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"182472","DOI":"10.1155\/2013\/182472","article-title":"Thyroid autoantibodies in pregnancy: their role, regulation and clinical relevance","volume":"2013","author":"Balucan FS, Morshed SA, Davies TF","year":"2013","unstructured":"34. Balucan FS, Morshed SA, Davies TF, Thyroid autoantibodies in pregnancy: their role, regulation and clinical relevance, J Thyroid Res, 2013;2013182472","journal-title":"J Thyroid Res"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"719","DOI":"10.1111\/cen.14853","article-title":"Maternal hypothyroidism and adverse outcomes of pregnancy","volume":"98","author":"Kn\u00f8sgaard L, Andersen S, Hansen AB, Vestergaard P, Andersen SL","year":"2023","unstructured":"35. Kn\u00f8sgaard L, Andersen S, Hansen AB, Vestergaard P, Andersen SL, Maternal hypothyroidism and adverse outcomes of pregnancy, Clin Endocrinol (Oxf), 2023;98719-729","journal-title":"Clin Endocrinol (Oxf)"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3310\/eme06110","article-title":"Levothyroxine to increase live births in euthyroid women with thyroid antibodies trying to conceive: the TABLET RCT","volume":"6","author":"Dhillon-Smith RK, Middleton LJ, Sunner KK, Cheed V, Baker K, Farrell-Carver S","year":"2019","unstructured":"36. Dhillon-Smith RK, Middleton LJ, Sunner KK, Cheed V, Baker K, Farrell-Carver S, Levothyroxine to increase live births in euthyroid women with thyroid antibodies trying to conceive: the TABLET RCT, Effic Mech Eval, 2019;61-72","journal-title":"Effic Mech Eval"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"101320","DOI":"10.1016\/j.beem.2019.101320","article-title":"Universal screening for thyroid disease during pregnancy should be performed","volume":"34","author":"Stagnaro-Green A, Dong A, Stephenson MD","year":"2020","unstructured":"37. Stagnaro-Green A, Dong A, Stephenson MD, Universal screening for thyroid disease during pregnancy should be performed, Best Pract Res Clin Endocrinol Metab, 2020;34101320","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1089\/thy.2016.0457","article-title":"2017 guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and the postpartum","volume":"27","author":"Alexander EK, Pearce EN, Brent GA, Brown RS, Chen H, Dosiou C","year":"2017","unstructured":"38. Alexander EK, Pearce EN, Brent GA, Brown RS, Chen H, Dosiou C, 2017 guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and the postpartum, Thyroid, 2017;27315-389","journal-title":"Thyroid"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1159\/000512790","article-title":"2021 European Thyroid Association guideline on thyroid disorders prior to and during assisted reproduction","volume":"9","author":"Poppe K, Bisschop P, Fugazzola L, Minziori G, Unuane D, Weghofer A","year":"2020","unstructured":"39. Poppe K, Bisschop P, Fugazzola L, Minziori G, Unuane D, Weghofer A, 2021 European Thyroid Association guideline on thyroid disorders prior to and during assisted reproduction, Eur Thyroid J, 2020;9281-295","journal-title":"Eur Thyroid J"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"282","DOI":"10.3399\/bjgp19X703805","article-title":"Thyroid hormone replacement in the preconception period and pregnancy","volume":"69","author":"Tran A, Hyer S, Rafi I, Okosieme O","year":"2019","unstructured":"40. Tran A, Hyer S, Rafi I, Okosieme O, Thyroid hormone replacement in the preconception period and pregnancy, Br J Gen Pract, 2019;69282-283","journal-title":"Br J Gen Pract"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"1316","DOI":"10.1056\/NEJMoa1812537","article-title":"Levothyroxine in women with thyroid peroxidase antibodies before conception","volume":"380","author":"Dhillon-Smith RK, Middleton LJ, Sunner KK, Cheed V, Baker K, Farrell-Carver S","year":"2019","unstructured":"41. Dhillon-Smith RK, Middleton LJ, Sunner KK, Cheed V, Baker K, Farrell-Carver S, Levothyroxine in women with thyroid peroxidase antibodies before conception, N Engl J Med, 2019;3801316-1325","journal-title":"N Engl J Med"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"334","DOI":"10.1210\/jc.2011-2576","article-title":"Approach to the patient with postpartum thyroiditis","volume":"97","author":"Stagnaro-Green A","year":"2012","unstructured":"42. Stagnaro-Green A, Approach to the patient with postpartum thyroiditis, J Clin Endocrinol Metab, 2012;97334-342","journal-title":"J Clin Endocrinol Metab"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"11823","DOI":"10.3390\/ijms262411823","article-title":"Epigenetic mechanisms in autoimmune thyroid diseases: bridging research and clinical applications","volume":"26","author":"Xiao S, Hu Y, Wang X, Yu H","year":"2025","unstructured":"43. Xiao S, Hu Y, Wang X, Yu H, Epigenetic mechanisms in autoimmune thyroid diseases: bridging research and clinical applications, Int J Mol Sci, 2025;2611823","journal-title":"Int J Mol Sci"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"953465","DOI":"10.3389\/fimmu.2022.953465","article-title":"Emerging trends and hot spots in autoimmune thyroiditis research from 2000 to 2022: a bibliometric analysis","volume":"13","author":"Li Q, Yang W, Li J, Shan Z","year":"2022","unstructured":"44. Li Q, Yang W, Li J, Shan Z, Emerging trends and hot spots in autoimmune thyroiditis research from 2000 to 2022: a bibliometric analysis, Front Immunol, 2022;13953465","journal-title":"Front Immunol"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"1662521","DOI":"10.3389\/fimmu.2025.1662521","article-title":"Recent advances of trace elements in autoimmune thyroid disease","volume":"16","author":"Li S, Xu Q, Wang S, Peng H, Liu Y","year":"2025","unstructured":"45. Li S, Xu Q, Wang S, Peng H, Liu Y, Recent advances of trace elements in autoimmune thyroid disease, Front Immunol, 2025;161662521","journal-title":"Front Immunol"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"2234","DOI":"10.3390\/nu14112234","article-title":"Selenium supplementation in pregnant women with autoimmune thyroiditis: a practical approach","volume":"14","author":"Minnetti M, Sada V, Feola T, Giannetta E, Pozza C, Gianfrilli D","year":"2022","unstructured":"46. Minnetti M, Sada V, Feola T, Giannetta E, Pozza C, Gianfrilli D, Selenium supplementation in pregnant women with autoimmune thyroiditis: a practical approach, Nutrients, 2022;142234","journal-title":"Nutrients"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"1495","DOI":"10.3390\/biomedicines13061495","article-title":"Hashimoto\u2019s thyroiditis and female fertility: endocrine, immune, and microbiota perspectives in assisted reproduction\u2014a narrative review","volume":"13","author":"Popa EC, Maghiar L, Maghiar TA, Brihan I, Georgescu LM, Todera\u0219 BA","year":"2025","unstructured":"47. Popa EC, Maghiar L, Maghiar TA, Brihan I, Georgescu LM, Todera\u0219 BA, Hashimoto\u2019s thyroiditis and female fertility: endocrine, immune, and microbiota perspectives in assisted reproduction\u2014a narrative review, Biomedicines, 2025;131495","journal-title":"Biomedicines"},{"key":"ref48","doi-asserted-by":"publisher","DOI":"10.1097\/j.pbj.0000000000000307","article-title":"Autoimmune thyroid disease in infertility and assisted reproductive technology: a review","volume":"10","author":"Pires MI, P\u00f3voa AM, Silva-Soares S","year":"2025","unstructured":"48. Pires MI, P\u00f3voa AM, Silva-Soares S, Autoimmune thyroid disease in infertility and assisted reproductive technology: a review, Porto Biomed J, 2025;10","journal-title":"Porto Biomed J"}],"container-title":["Journal of Medicine and Life"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/medandlife.org\/all-issues\/2026\/issue-6-2026\/review-issue-6-2026\/autoimmune-thyroiditis-in-pregnancy-epidemiology-clinical-impact-and-contemporary-management-challenges\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T08:34:31Z","timestamp":1788770071000},"score":1,"resource":{"primary":{"URL":"https:\/\/medandlife.org\/all-issues\/2026\/issue-6-2026\/review-issue-6-2026\/autoimmune-thyroiditis-in-pregnancy-epidemiology-clinical-impact-and-contemporary-management-challenges\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":48,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["JMedLife-19-426"],"URL":"https:\/\/doi.org\/10.25122\/jml-2026-0019","relation":{},"ISSN":["1844-3117"],"issn-type":[{"value":"1844-3117","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6]]}}}