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To address this challenge, we propose a novel approach to flight test analysis using Gaussian processes (GPs) with physics-informed mean functions to estimate aerodynamic quantities from arbitrary flight test data, validated using real T-38 aircraft data collected in collaboration with the United States Air Force Test Pilot School. We demonstrate our method by estimating the pitching moment coefficient [Formula: see text] without requiring predefined or repeated flight test points, significantly reducing the need for extensive experimental campaigns. Our approach incorporates aerodynamic models as priors within the GP framework, enhancing predictive accuracy across diverse flight conditions and providing robust uncertainty quantification. Key contributions include the integration of physics-based priors in a probabilistic model, which allows for precise computation from arbitrary flight test maneuvers, and the demonstration of our method capturing relevant dynamic characteristics such as short-period mode behavior. The proposed framework offers a scalable and generalizable solution for efficient data-driven flight test analysis and is able to accurately predict the short-period frequency and damping for the T-38 across several Mach and dynamic pressure profiles. **<\/jats:p>","DOI":"10.2514\/1.i011606","type":"journal-article","created":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T15:53:59Z","timestamp":1770306839000},"page":"271-278","update-policy":"https:\/\/doi.org\/10.2514\/aiaa_crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Physics-Informed Gaussian Processes for Efficient Envelope Expansion"],"prefix":"10.2514","volume":"23","author":[{"given":"D. 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