{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T16:11:04Z","timestamp":1791907864952,"version":"4.3.4"},"reference-count":108,"publisher":"Journal of Orthopaedic & Sports Physical Therapy (JOSPT)","issue":"2","content-domain":{"domain":["www.jospt.org"],"crossmark-restriction":true},"short-container-title":["Journal of Orthopaedic &amp; Sports Physical Therapy"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:p> OBJECTIVE: To compare the effectiveness of injury prevention programs (IPPs) for improving high-risk knee motion patterns in the context of reducing the risk of noncontact anterior cruciate ligament injury. <\/jats:p><jats:p> DESIGN: Systematic review with Bayesian network meta-analysis. <\/jats:p><jats:p> DATA SOURCES: PubMed, Embase, Web of Science, Cochrane Library, and the Cumulative Index to Nursing and Allied Health Literature were searched until September 10, 2023. <\/jats:p><jats:p> ELIGIBILITY CRITERIA: We included randomized controlled trials involving athletes without prior anterior cruciate ligament injury. The trials had to provide data on peak knee flexion and valgus angles, obtained from 2-leg drop vertical jump, single-leg drop vertical jump, or side-step cutting test. <\/jats:p><jats:p> RESULTS: The network meta-analysis synthesized data from 22 randomized controlled trials involving 878 participants, evaluating 12 different IPPs. Results of meta-analyses indicated that, in jumping tests, the external focus instructions (mean difference [MD] = 26; credible interval [CrI] = 7.5, 44; surface under the cumulative ranking curve [SUCRA] = 0.94) and internal focus of attention (MD = 19; CrI = 0.19, 37; SUCRA = 0.81) was effective for increasing peak knee flexion, and core stability training ranked first for reducing knee valgus (MD = \u22124.40; CrI = \u22127.7, \u22121.1; SUCRA = 0.96). None of the IPPs revealed statistically significant effects for the cutting test. <\/jats:p><jats:p> CONCLUSION: The external focus instructions and internal focus of attention increased knee flexion, while core stability exercise reduced knee valgus in jumping tests. Intervention effects were inconsistent for cutting tests. J Orthop Sports Phys Ther 2025;55(2):123-136. 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