{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T00:38:07Z","timestamp":1791851887136,"version":"4.3.4"},"reference-count":40,"publisher":"Journal of Orthopaedic & Sports Physical Therapy (JOSPT)","issue":"1","content-domain":{"domain":["www.jospt.org"],"crossmark-restriction":true},"short-container-title":["JOSPT Open"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>OBJECTIVE: To identify patient subgroups based on their perceived importance of improvement across multiple domains (pain, fatigue, emotional distress, and interference) using the Patient-Centered Outcomes Questionnaire. Additionally, we examined the association between subgroups, treatment expectations, therapeutic alliance, and clinical outcomes.<\/jats:p>\n                  <jats:p>DESIGN: A prospective cohort study conducted in a university-based outpatient physical therapy clinic.<\/jats:p>\n                  <jats:p>METHODS: Patients (N = 169) with musculoskeletal conditions completed the Patient-Centered Outcomes Questionnaire, the Credibility and Expectancy Questionnaire, and the Working Alliance Inventory\u2013Short Form Revised (WAI-SR). Cluster analysis identified patient subgroups based on their improvement priorities. Differences between subgroups in expectations, therapeutic alliance, and changes in pain and function were analyzed using t tests and analysis of variance.<\/jats:p>\n                  <jats:p>RESULTS: Two- and three-cluster solutions were considered. In both solutions, 2 subgroups emerged rating all domains as highly important, 1 subgroup, Global Importance, and a second subgroup prioritizing pain and interference, Pain and Function. The 3-cluster solution identified a subgroup characterized by high importance ratings for pain, interference, and fatigue ( Pain and Function with Fatigue). The Global Importance groups reported significantly higher expectations for treatment success ( P = .025, P = .008). The Global Importance subgroup from the 2-cluster solution also reported stronger therapeutic alliance ( P = .032). No differences were found between subgroups in pain or functional improvements.<\/jats:p>\n                  <jats:p>CONCLUSION: In this exploratory analysis, the Global Importance subgroups had stronger therapeutic alliance and higher expectations for treatment success. JOSPT Open 2026;4(1):91-100. 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