{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T09:16:45Z","timestamp":1780391805855,"version":"3.54.1"},"reference-count":52,"publisher":"Oxford University Press (OUP)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,2,1]]},"abstract":"<jats:sec><jats:title>Background and Purpose<\/jats:title><jats:p>Traditional vestibular function testing has measured horizontal semicircular canal function only. Otolith function tests have recently been developed, but their clinical significance has not been determined. The purpose of this study was to investigate the influence of otolith dysfunction on the clinical presentation of individuals with a peripheral vestibular disorder.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects and Methods<\/jats:title><jats:p>Twenty-one subjects with loss of horizontal semicircular canal function only and 37 subjects with combined loss of horizontal semicircular canal and otolith organ function were recruited. All subjects received a comprehensive clinical assessment, including self-report questionnaires and measures of balance performance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>No significant differences were identified between subjects with or without otolith dysfunction with respect to symptom severity, self-perceived handicap, functional limitations, or balance performance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion and Conclusion<\/jats:title><jats:p>Otolith dysfunction does not significantly influence the clinical presentation of individuals with a peripheral vestibular disorder. Other factors, including symptom severity, may be more influential.<\/jats:p><\/jats:sec>","DOI":"10.2522\/ptj.20060004","type":"journal-article","created":{"date-parts":[[2007,2,16]],"date-time":"2007-02-16T22:08:35Z","timestamp":1171663715000},"page":"143-152","source":"Crossref","is-referenced-by-count":18,"title":["The Influence of Otolith Dysfunction on the Clinical Presentation of People With a Peripheral Vestibular Disorder"],"prefix":"10.1093","volume":"87","author":[{"given":"Kate J","family":"Murray","sequence":"first","affiliation":[{"name":"KJ Murray, PhD, is Physiotherapist, Dizzy Day Clinics, Melbourne, Victoria, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith D","family":"Hill","sequence":"additional","affiliation":[{"name":"KD Hill, PhD, is Director, Preventive and Public Health Division, National Ageing Research Institute, and School of Physiotherapy, The University of Melbourne, Melbourne, Victoria, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bev","family":"Phillips","sequence":"additional","affiliation":[{"name":"B Phillips, PhD, is Associate Professor of Allied Health, School of Physiotherapy, LaTrobe University, Melbourne, Victoria, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Waterston","sequence":"additional","affiliation":[{"name":"J Waterston, MD, FRACP, is Neurologist and Senior Lecturer, Department of Medicine, Monash University, Melbourne, Victoria, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","reference":[{"key":"2019123111382314100_B1","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1093\/brain\/115.3.647","article-title":"Neurology of otolith function: peripheral and central disorders","volume":"115","author":"Gresty","year":"1992","journal-title":"Brain"},{"key":"2019123111382314100_B2","first-page":"23","article-title":"Role of the vestibular system in postural control","volume-title":"Vestibular Rehabilitation","author":"Horak","year":"1994"},{"key":"2019123111382314100_B3","first-page":"132","article-title":"Testing the vestibulo-ocular reflex","volume":"53","author":"Halmagyi","year":"1997","journal-title":"Adv Otolaryngol"},{"key":"2019123111382314100_B4","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1080\/00016489950181495","article-title":"The Subjective Visual Vertical as a clinical parameter for acute and chronic vestibular (otolith) disorders","volume":"119","author":"Bohmer","year":"1999","journal-title":"Acta Otolaryngol (Stock)"},{"key":"2019123111382314100_B5","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1111\/j.1749-6632.1999.tb09187.x","article-title":"Assessing otolith function by the Subjective Visual Vertical","volume":"871","author":"Bohmer","year":"1999","journal-title":"Ann NY Acad Sci"},{"key":"2019123111382314100_B6","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1001\/archotol.128.1.21","article-title":"Vibration-induced shift of the Subjective Visual Horizontal","volume":"128","author":"Karlberg","year":"2002","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"2019123111382314100_B7","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.1212\/WNL.42.8.1635","article-title":"Vestibular evoked potentials in human neck muscles before and after unilateral deafferentation","volume":"42","author":"Colebatch","year":"1992","journal-title":"Neurology"},{"key":"2019123111382314100_B8","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1097\/00019052-200102000-00004","article-title":"Vestibular evoked potentials","volume":"14","author":"Colebatch","year":"2001","journal-title":"Curr Opin Neurol"},{"key":"2019123111382314100_B9","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1136\/jnnp.66.6.787","article-title":"Click evoked myogenic potentials in the differential diagnosis of acute vertigo","volume":"66","author":"Heide","year":"1999","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"2019123111382314100_B10","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1016\/S1388-2457(02)00155-4","article-title":"Vestibular evoked myogenic potentials in multiple sclerosis patients","volume":"113","author":"Versino","year":"2002","journal-title":"Clin Neurophysiol"},{"key":"2019123111382314100_B11","doi-asserted-by":"crossref","first-page":"170","DOI":"10.3109\/00016489609137816","article-title":"Diplopia from skew deviation in unilateral peripheral vestibular lesions","volume":"116","author":"Vibert","year":"1996","journal-title":"Acta Otolaryngol. 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