{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T05:54:06Z","timestamp":1790834046497,"version":"4.1.0"},"reference-count":68,"publisher":"Oxford University Press (OUP)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015,11,1]]},"abstract":"<jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Multiple dimensions across the biopsychosocial spectrum are relevant in the management of nonspecific chronic low back pain (NSCLBP). Cognitive functional therapy is a behaviorally targeted intervention that combines normalization of movement and abolition of pain behaviors with cognitive reconceptualization of the NSCLBP problem while targeting psychosocial and lifestyle barriers to recovery.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>The purpose of this study was to examine the effectiveness of cognitive functional therapy for people with disabling NSCLBP who were awaiting an appointment with a specialist medical consultant.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Design<\/jats:title>\n                  <jats:p>A multiple case-cohort study (n=26) consisting of 3 phases (A1\u2013B\u2013A2) was conducted.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Measurement phase A1 was a baseline phase during which measurements of pain and functional disability were collected on 3 occasions over 3 months for all participants. During phase B, participants entered a cognitive functional therapy intervention program involving approximately 8 treatments over an average of 12 weeks. Finally, phase A2 was a 12-month, no-treatment follow-up period. Outcomes were analyzed using repeated-measures analysis of variance or Friedman test (with post hoc Bonferroni correction) across 7 time intervals, depending on normality of data distribution.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Statistically significant reductions in both functional disability and pain were observed immediately postintervention and were maintained over the 12-month follow-up period. These reductions reached clinical significance for both disability and pain. Secondary psychosocial outcomes, including depression, anxiety, back beliefs, fear of physical activity, catastrophizing, and self-efficacy, were significantly improved after the intervention.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Limitations<\/jats:title>\n                  <jats:p>The study was not a randomized controlled trial. Although primary outcome data were self-reported, the assessor was not blinded.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>These promising results suggest that cognitive functional therapy should be compared with other conservative interventions for the management of disabling NSCLBP in secondary care settings in large randomized clinical trials.<\/jats:p>\n               <\/jats:sec>","DOI":"10.2522\/ptj.20140406","type":"journal-article","created":{"date-parts":[[2015,4,30]],"date-time":"2015-04-30T21:22:43Z","timestamp":1430428963000},"page":"1478-1488","source":"Crossref","is-referenced-by-count":89,"title":["Cognitive Functional Therapy for Disabling Nonspecific Chronic Low Back Pain: Multiple Case-Cohort Study"],"prefix":"10.1093","volume":"95","author":[{"given":"Kieran","family":"O'Sullivan","sequence":"first","affiliation":[{"name":"K. O'Sullivan, PhD, MManipTher, BPhysio, Department of Clinical Therapies, University of Limerick, Limerick, Ireland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wim","family":"Dankaerts","sequence":"additional","affiliation":[{"name":"W. Dankaerts, PhD, PGDipManipTher, BScPhysio, Department of Rehabilitation Sciences, University of Leuven, Leuven, Belgium."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonard","family":"O'Sullivan","sequence":"additional","affiliation":[{"name":"L. O'Sullivan, PhD, MTech, BTech, Department of Design and Manufacturing Technology, University of Limerick."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter B.","family":"O'Sullivan","sequence":"additional","affiliation":[{"name":"P.B. 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