{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T14:54:44Z","timestamp":1772463284845,"version":"3.50.1"},"reference-count":46,"publisher":"Scientific Scholar","content-domain":{"domain":["ijdvl.com"],"crossmark-restriction":true},"short-container-title":["IJDVL"],"abstract":"Background:<\/jats:title>The prevalence of dermatophytes varies with season, geographical area, socio-economic factors and effective management strategies.<\/jats:p><\/jats:sec>Aims:<\/jats:title>The aim of the study was to assess the prevalence of pathogenic dermatophytes, clinical types of dermatophyte fungal infection, andin vitro<\/jats:italic>antifungal drug susceptibility testing against dermatophytes.<\/jats:p><\/jats:sec>Methods:<\/jats:title>Three hundred and ninety five patients with dermatophytosis were enrolled from five cities (Mumbai, Delhi, Lucknow, Kolkata and Hyderabad) across India. All patients were subjected to clinical examination and investigations, including potassium hydroxide microscopy, fungal culture and antifungal drug susceptibility testing.<\/jats:p><\/jats:sec>Results:<\/jats:title>Trichophyton rubrum<\/jats:italic>was the most common species identified (68.4%), followed byT. mentagrophytes<\/jats:italic>(29.3%). Within species,T. mentagrophytes<\/jats:italic>was prevalent in humid environmental conditions (Mumbai and Kolkata), whereasT. rubrum<\/jats:italic>was prevalent in noncoastal areas (Delhi, Lucknow and Hyderabad). Tinea corporis (71.4%) and tinea cruris (62.0%) were the common clinical types observed. antifungal drug susceptibility testing data indicated that minimum inhibitory concentration required to inhibit the growth of 90% of organisms (MIC-90) was lowest for griseofulvin (0.25\u20133.0 \u03bcg\/mL). Among oral antifungals, the mean MIC of itraconazole was within the range (0.84 [0.252] \u03bcg\/ mL), whereas high mean MIC values were reported for terbinafine (0.05 [0.043] \u03bcg\/mL). Among topical agents, lowest mean MIC values were reported for luliconazole (0.29 [0.286] \u03bcg\/mL), eberconazole (0.32 [0.251]) \u03bcg\/mL and amorolfine (0.60 [0.306]) \u03bcg\/mL.<\/jats:p><\/jats:sec>Limitations:<\/jats:title>Lack of correlation betweenin vitro<\/jats:italic>antifungal susceptibility and clinical outcome and absence of defined MIC breakpoints.<\/jats:p><\/jats:sec>Conclusion:<\/jats:title>T. rubrum<\/jats:italic>was the most common, followed byT. mentagrophytes<\/jats:italic>as an emerging\/codominant fungal isolate in India. Tinea corporis was the most common clinical type of dermatophytosis. Mean MIC of terbinafine was above the reference range, while it was within the range for itraconazole; griseofulvin had the lowest mean MIC. Luliconazole presented the lowest mean MIC values across cities.<\/jats:p><\/jats:sec>","DOI":"10.25259\/ijdvl_1025_19","type":"journal-article","created":{"date-parts":[[2021,6,7]],"date-time":"2021-06-07T18:42:54Z","timestamp":1623091374000},"page":"800-806","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Etiological prevalence and antifungal sensitivity patterns of dermatophytosis in India \u2013 A multicentric study"],"prefix":"10.25259","volume":"87","author":[{"given":"Sushil","family":"Tahiliani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abir","family":"Saraswat","sequence":"additional","affiliation":[{"name":"Indushree Skin Clinic, Near Hotel Bandhan, Faizabad Road, Indiranagar Colony, Lucknow, Uttar Pradesh, India,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. 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Narasimha","family":"Rao","sequence":"additional","affiliation":[{"name":"Comprehensive Dermatology Clinic, Plot No 4, Satya Apartment, Masab Tank, Opposite Polytechnic College, Beside Golconda Hotel, Hyderabad, Telangana, India,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Potharaju Arun","family":"Raghav","sequence":"additional","affiliation":[{"name":"Comprehensive Dermatology Clinic, Plot No 4, Satya Apartment, Masab Tank, Opposite Polytechnic College, Beside Golconda Hotel, Hyderabad, Telangana, India,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pramod","family":"Agarwal","sequence":"additional","affiliation":[{"name":"Yuva Skin and Laser Center, A-1031, A-Block, Indira Nagar, Lucknow, Uttar Pradesh, India,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. D.","family":"Kharkar","sequence":"additional","affiliation":[{"name":"Dr. Kharkar's Skin Clinic, Room No 55 , 5th Floor, Dattani Chambers, S V Road, Opposite Shantinath Shopping Centre, Malad West, Mumbai, Maharashtra, India,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. 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