{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T19:21:31Z","timestamp":1790709691527,"version":"4.1.0"},"reference-count":8,"publisher":"Scientific Scholar","content-domain":{"domain":["ijdvl.com"],"crossmark-restriction":true},"short-container-title":["Indian J Dermatol Venereol Leprol"],"abstract":"\n Background<\/jats:title>\n Pemphigus vulgaris is a chronic autoimmune blistering disorder that primarily affects the oral mucosa, with over two-thirds of patients developing oral lesions, often preceding skin involvement by weeks or months. The oral disease severity score (ODSS) provides a detailed, region-specific assessment of oral lesions, facilitating regular monitoring and treatment response. However, it lacks a comprehensive severity evaluation cut-offs needed for systemic therapy decisions.<\/jats:p>\n <\/jats:sec>\n \n Aim<\/jats:title>\n To categorise oral pemphigus severity into moderate, significant, and extensive using ODSS.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n The study included 25 oral pemphigus patients, confirmed histopathologically or by anti-DSG 3, evaluated severity using ODSS and PDAI scales, with statistical significance analysed between the scores and categories.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n The study comprised 25 subjects with a mean age of 47.48 years (\u00b115.692), including 8 males (32%) and 17 (68%) females. The mean ODSS and PDAI scores were 30.12 (\u00b113.902) and 20.72 (\u00b114.105), respectively. A highly significant positive correlation (r=0.962, p-value <0.001) was observed between PDAI and ODSS scores. An AUC value (>0.8) confirmed ODSS\u2019s good discriminating ability, categorising oral pemphigus severity: <21.5 as moderate, 21.5\u201348.5 as significant, and >48.5 as extensive, as per PDAI criteria.<\/jats:p>\n <\/jats:sec>\n \n Limitation<\/jats:title>\n Small sample size is the major limitation of this study.<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n This study proposes severity categories for ODSS for oral pemphigus, allowing it to be used for personalised treatment decisions.<\/jats:p>\n <\/jats:sec>","DOI":"10.25259\/ijdvl_1527_2024","type":"journal-article","created":{"date-parts":[[2025,4,16]],"date-time":"2025-04-16T06:07:22Z","timestamp":1744783642000},"page":"371-375","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Correlating pemphigus disease area index (PDAI) severity categories with oral disease severity score (ODSS) in oral mucosal pemphigus - A pilot study"],"prefix":"10.25259","volume":"92","author":[{"given":"Arun Dev","family":"Sharma","sequence":"first","affiliation":[{"name":"Department of Oral Medicine and Radiology, Government College of Dentistry, Indore, Madhya Pradesh, India,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prashanthi","family":"Reddy","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, Government College of Dentistry, Indore, Madhya Pradesh, India,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajay","family":"Parihar","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, Government College of Dentistry, Indore, Madhya Pradesh, India,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sujata","family":"Tosh","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, Government College of Dentistry, Indore, Madhya Pradesh, India,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rashi","family":"Mandlik","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, Government College of Dentistry, Indore, Madhya Pradesh, India,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nidhi","family":"Yadav","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, Government College of Dentistry, Indore, Madhya Pradesh, India,"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2025,4,15]]},"reference":[{"key":"10.25259\/IJDVL_1527_2024\/ref-1","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1080\/08916930600971414","article-title":"Pemphigus in the XXI century: New life to an old story","volume":"39","author":"Grando","year":"2006","journal-title":"Autoimmunity"},{"key":"10.25259\/IJDVL_1527_2024\/ref-2","doi-asserted-by":"publisher","first-page":"17026","DOI":"10.1038\/nrdp.2017.26","article-title":"Pemphigus","volume":"3","author":"Kasperkiewicz","year":"2017","journal-title":"Nat Rev Dis Primers"},{"key":"10.25259\/IJDVL_1527_2024\/ref-3","doi-asserted-by":"publisher","first-page":"1729","DOI":"10.1056\/NEJM199012203232503","article-title":"Paraneoplastic pemphigus. An autoimmune mucocutaneous disease associated with neoplasia","volume":"323","author":"Anhalt","year":"1990","journal-title":"N Engl J Med"},{"key":"10.25259\/IJDVL_1527_2024\/ref-4","doi-asserted-by":"publisher","first-page":"1043","DOI":"10.1016\/j.jaad.2008.01.012","article-title":"Consensus statement on definitions of disease, end points, and therapeutic response for pemphigus","volume":"58","author":"Murrell","year":"2008","journal-title":"J Am Acad Dermatol"},{"key":"10.25259\/IJDVL_1527_2024\/ref-5","doi-asserted-by":"publisher","first-page":"872","DOI":"10.1111\/bjd.16265","article-title":"An oral disease severity score validated for use in oral pemphigus vulgaris","volume":"179","author":"Ormond","year":"2018","journal-title":"Br J Dermatol"},{"key":"10.25259\/IJDVL_1527_2024\/ref-6","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1111\/j.1365-263X.2005.00640.x","article-title":"Oral pemphigus vulgaris in children and adolescents: A review of the literature and a case report","volume":"15","author":"Ariyawardana","year":"2005","journal-title":"Int J Paediatr Dent"},{"key":"10.25259\/IJDVL_1527_2024\/ref-7","first-page":"43","volume-title":"Burket\u2019s oral medicine","author":"Glick","year":"2022","edition":"13th edition"},{"key":"10.25259\/IJDVL_1527_2024\/ref-8","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1016\/j.jaad.2018.02.021","article-title":"Diagnosis and management of pemphigus: Recommendations of an international panel of experts","volume":"82","author":"Murrell","year":"2020","journal-title":"J Am Acad Dermatol"}],"container-title":["Indian Journal of Dermatology, Venereology and Leprology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ijdvl.com\/correlating-pemphigus-disease-area-index-pdai-severity-categories-with-oral-disease-severity-score-odss-in-oral-mucosal-pemphigus-a-pilot-study\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ijdvl.com\/correlating-pemphigus-disease-area-index-pdai-severity-categories-with-oral-disease-severity-score-odss-in-oral-mucosal-pemphigus-a-pilot-study\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T07:32:36Z","timestamp":1778139156000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ijdvl.com\/correlating-pemphigus-disease-area-index-pdai-severity-categories-with-oral-disease-severity-score-odss-in-oral-mucosal-pemphigus-a-pilot-study\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,15]]},"references-count":8,"alternative-id":["10.25259\/IJDVL_1527_2024"],"URL":"https:\/\/doi.org\/10.25259\/ijdvl_1527_2024","relation":{},"ISSN":["0973-3922","0378-6323"],"issn-type":[{"value":"0973-3922","type":"electronic"},{"value":"0378-6323","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4,15]]},"article-number":"371"}}