{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,2,22]],"date-time":"2024-02-22T00:52:14Z","timestamp":1708563134367},"reference-count":30,"publisher":"Scientific Scholar","content-domain":{"domain":["ijdvl.com"],"crossmark-restriction":true},"short-container-title":["IJDVL"],"abstract":"<jats:sec id=\"st1\">\n<jats:title>Background<\/jats:title>\n<jats:p>Of all the tissue or cellular grafting techniques used in the treatment of vitiligo, melanocyte transplant\/transfer through ultrathin skin grafting (UTSG) provides rapid onset of regimentation. The regimentation process is further accelerated with a combination of psoralen and ultraviolet A radiation, or psoralen and ultraviolet A obtained by sunlight or narrowband ultraviolet light B, or excimer laser\/lamp (308 nm).<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st2\">\n<jats:title>Aims<\/jats:title>\n<jats:p>We assessed the efficacy of carbon dioxide laser ablation followed by melanocyte transplant\/transfer through ultrathin skin graft sheet\/sheets and further treated by excimer lamp therapy in patients with stable vitiligo.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st3\">\n<jats:title>Methods<\/jats:title>\n<jats:p>One hundred ninety-two patients with stable vitiligo were treated with UTSG following carbon dioxide laser ablation and patients were then put on excimer lamp therapy. Primary efficacy was determined in terms of grades of regimentation and colour match at the end of 1-year.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st4\">\n<jats:title>Results<\/jats:title>\n<jats:p>A total of 192 stable vitiligo patients with a mean age of 32.71 \u00b1 8.55 years were recruited. Of the total 410 lesions, 394 showed excellent regimentation indicating a success rate of 96.1% at 1-year follow-up, whereas 16 (3.9%) lesions present on fingertips and toe tips showed poor or no regimentation at 3-month and 1-year follow-up. With regards to colour match, 394 (96.1%) lesions had achieved excellent colour match, and 16 lesions (3.9%) had poor or no colour match at 1-year follow-up.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st5\">\n<jats:title>Limitations<\/jats:title>\n<jats:p>This was a single-center study with a small sample size.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st6\">\n<jats:title>Conclusion<\/jats:title>\n<jats:p>The effectiveness of carbon dioxide laser ablation followed by melanocyte transfer\/transplant through ultra-thin skin graft sheet\/sheets when combined with excimer lamp therapy provides favourable cosmetic outcomes with rapid onset of regimentation in stable vitiligo.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/ijdvl_408_2022","type":"journal-article","created":{"date-parts":[[2023,5,8]],"date-time":"2023-05-08T09:41:34Z","timestamp":1683538894000},"page":"150-157","update-policy":"http:\/\/dx.doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Retrospective analysis of ultrathin skin grafting over carbon dioxide ablated lesions supplemented with excimer lamp (308 nm) therapy in stable vitiligo"],"prefix":"10.25259","volume":"90","author":[{"given":"Sushil S.","family":"Savant Jr","sequence":"first","affiliation":[{"name":"Department of Dermatology, The Humanitarian Clinic: Skin, Hair and Laser Centre, Mumbai, Maharashtra, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satish S.","family":"Savant","sequence":"additional","affiliation":[{"name":"Department of Dermatology, The Humanitarian Clinic: Skin, Hair and Laser Centre, Mumbai, Maharashtra, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2023,5,3]]},"reference":[{"key":"10.25259\/IJDVL_408_2022\/ref-1","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1046\/j.1468-3083.2003.00718.x","article-title":"Surgical treatment of vitiligo; why, when and how","volume":"17","author":"Falabella","year":"2003","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.25259\/IJDVL_408_2022\/ref-2","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1046\/j.1468-3083.2002.00590.x","article-title":"Psychiatric morbidity in vitiligo: Prevalence and correlates in India","volume":"16","author":"Mattoo","year":"2002","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.25259\/IJDVL_408_2022\/ref-3","doi-asserted-by":"publisher","first-page":"E1","DOI":"10.1111\/j.1755-148X.2012.00997.x","article-title":"Revised classification\/nomenclature of vitiligo and related issues: The Vitiligo Global Issues Consensus Conference","volume":"25","author":"Ezzedine","year":"2012","journal-title":"Pigment Cell Melanoma Res"},{"key":"10.25259\/IJDVL_408_2022\/ref-4","first-page":"S37","article-title":"IADVL dermatosurgery task force. Standard guidelines of care for vitiligo surgery","volume":"74","author":"Parsad","year":"2008","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"10.25259\/IJDVL_408_2022\/ref-5","doi-asserted-by":"publisher","first-page":"307","DOI":"10.4103\/0378-6323.16778","article-title":"Surgical therapy of vitiligo: Current status","volume":"71","author":"Savant","year":"2005","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"10.25259\/IJDVL_408_2022\/ref-6","first-page":"310","article-title":"Autologous miniaturepunch skin grafting in stable vitiligo","volume":"58","author":"Savant","year":"1992","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"10.25259\/IJDVL_408_2022\/ref-7","first-page":"117","article-title":"Autologous thin thiersch\u2019s grafts in vitiligo: Experience of 8000 cases, 50000 grafts (1959\u201398) with modified technique in 198 cases in the year 1997\u201398","volume":"65","author":"Behl","year":"1999","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"10.25259\/IJDVL_408_2022\/ref-8","doi-asserted-by":"publisher","first-page":"306","DOI":"10.1046\/j.1365-4362.1999.00702.x","article-title":"Modified technique of suction blistering for epidermal grafting in vitiligo","volume":"38","author":"Gupta","year":"1999","journal-title":"Int J Dermatol"},{"key":"10.25259\/IJDVL_408_2022\/ref-9","first-page":"365","article-title":"Repigmentation in vitiligo patients","volume":"24","author":"Kahn","year":"1998","journal-title":"Melanocyte transfer via ultra-thin grafts. Dermatol Surg"},{"key":"10.25259\/IJDVL_408_2022\/ref-10","first-page":"585","volume-title":"Ultrathin Skin Grafting (UTSG): Melanocyte transplant\/transfer. Textbook of dermatosurgery and cosmetology principles and practice","volume":"vol 45","author":"Savant","year":"2018","edition":"3rd ed"},{"key":"10.25259\/IJDVL_408_2022\/ref-11","doi-asserted-by":"publisher","first-page":"893","DOI":"10.1046\/j.1365-2133.2002.04837.x","article-title":"Long-term follow-up of leucoderma patients treated with transplants of autologous cultured melanocytes, ultrathin epidermal sheets and basal cell layer suspension","volume":"147","author":"Olsson","year":"2002","journal-title":"Br J Dermatol"},{"key":"10.25259\/IJDVL_408_2022\/ref-12","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1016\/0190-9622(92)70024-a","article-title":"Autologous grafting with noncultured melanocytes: A simplified method for treatment of depigmented lesions","volume":"26","author":"Gauthier","year":"1992","journal-title":"J Am Acad Dermatol"},{"key":"10.25259\/IJDVL_408_2022\/ref-13","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1016\/s0190-9622(89)70170-5","article-title":"Transplantation of in vitro-cultured epidermis bearing melanocytes for repigmenting vitiligo","volume":"21","author":"Falabella","year":"1989","journal-title":"J Am Acad Dermatol"},{"key":"10.25259\/IJDVL_408_2022\/ref-14","doi-asserted-by":"publisher","first-page":"1981","DOI":"10.1111\/dsu.12000","article-title":"Efficacy and safety of autologous cultured melanocytes delivered on poly (DL-lactic acid) film: A prospective, open-label, randomized, multicenter study","volume":"38","author":"Ghosh","year":"2012","journal-title":"Dermatol Surg"},{"key":"10.25259\/IJDVL_408_2022\/ref-15","doi-asserted-by":"publisher","first-page":"622","DOI":"10.4103\/0378-6323.45106","article-title":"Keratinocyte-Melanocyte graft technique followed by PUVA therapy for stable vitiligo","volume":"74","author":"Kachhawa","year":"2008","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"10.25259\/IJDVL_408_2022\/ref-16","doi-asserted-by":"publisher","first-page":"646","DOI":"10.1016\/0190-9622(95)91287-8","article-title":"Vitiligo: Treatment by dermabrasion and epithelial sheet grafting","volume":"33","author":"Kahn","year":"1995","journal-title":"J Am Acad Dermatol"},{"key":"10.25259\/IJDVL_408_2022\/ref-17","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1046\/j.1524-4725.1999.99093-2.x","article-title":"Repigmentation in vitiligo patients. Melanocyte transfer via ultra-thin grafts","volume":"25","author":"Kahn","year":"1999","journal-title":"Dermatol Surg"},{"key":"10.25259\/IJDVL_408_2022\/ref-18","doi-asserted-by":"publisher","first-page":"965","DOI":"10.1111\/j.1524-4725.1996.tb00642.x","article-title":"Grafting following short-pulse carbon dioxide laser de-epithelialization","volume":"22","author":"Kahn","year":"1996","journal-title":"Dermatol Surg"},{"key":"10.25259\/IJDVL_408_2022\/ref-19","doi-asserted-by":"publisher","first-page":"1291","DOI":"10.1097\/01.PRS.0000047023.07901.0A","article-title":"Carbon dioxide laser resurfacing and thin skin grafting in the treatment of \u201cstable and recalcitrant\u201d vitiligo","volume":"111","author":"Acikel","year":"2003","journal-title":"Plast Reconstr Surg"},{"key":"10.25259\/IJDVL_408_2022\/ref-20","doi-asserted-by":"publisher","first-page":"159","DOI":"10.4103\/0378-6323.93632","article-title":"Ultrathin split-thickness skin grafting followed by narrowband UVB therapy for stable vitiligo: An effective and cosmetically satisfying treatment option","volume":"78","author":"Majid","year":"2012","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"10.25259\/IJDVL_408_2022\/ref-21","doi-asserted-by":"crossref","first-page":"7436","DOI":"10.14260\/jemds\/2015\/1079","article-title":"Ultra thin epidermal skin grafting for stable vitiligo: a cost effective and cosmetically satisfying treatment option","volume":"43","author":"Pinjala","year":"2015","journal-title":"J Evol Med Dent Sci"},{"key":"10.25259\/IJDVL_408_2022\/ref-22","doi-asserted-by":"publisher","first-page":"150","DOI":"10.4103\/0019-5154.53196","article-title":"Tissue grafts in vitiligo surgery - past, present, and future","volume":"54","author":"Khunger","year":"2009","journal-title":"Indian J Dermatol"},{"key":"10.25259\/IJDVL_408_2022\/ref-23","doi-asserted-by":"publisher","first-page":"1448","DOI":"10.1111\/j.1468-3083.2009.03230.x","article-title":"Comparison of recipient site preparations in epidermal grafting for vitiligo: Suction blister and CO2 laser","volume":"23","author":"Lee","year":"2009","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.25259\/IJDVL_408_2022\/ref-24","first-page":"62:743","volume-title":"The Carbon Dioxide (CO2) and Erbium: YAG. Lasers: Textbook of Dermatosurgery and Cosmetology Principles and Practice","volume":"vol 63","author":"Savant","year":"2018","edition":"3rd ed"},{"key":"10.25259\/IJDVL_408_2022\/ref-25","doi-asserted-by":"publisher","first-page":"565","DOI":"10.1046\/j.1524-4725.2001.00334.x","article-title":"Treatment of vitiligo with suction epidermal grafting by the use of an Ultrapulse CO2 laser with a computerized pattern generator","volume":"27","author":"Oh","year":"2001","journal-title":"Dermatol Surg"},{"key":"10.25259\/IJDVL_408_2022\/ref-26","doi-asserted-by":"publisher","first-page":"2209","DOI":"10.1097\/00006534-199811000-00062","article-title":"Use of octyl-2-cyanoacrylate for skin closure in facial plastic surgery","volume":"102","author":"Toriumi","year":"1998","journal-title":"Plast Reconstr Surg"},{"key":"10.25259\/IJDVL_408_2022\/ref-27","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1111\/j.1524-4725.2010.01477.x","article-title":"Long-term results of split-skin grafting in combination with excimer laser for stable vitiligo","volume":"36","author":"Al-Mutairi","year":"2010","journal-title":"Dermatol Surg"},{"key":"10.25259\/IJDVL_408_2022\/ref-28","doi-asserted-by":"publisher","first-page":"690","DOI":"10.1111\/j.1468-3083.2011.04147.x","article-title":"A randomized comparison of excimer laser versus narrow-band ultraviolet B phototherapy after punch grafting in stable vitiligo patients","volume":"26","author":"Linthorst Homan","year":"2012","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.25259\/IJDVL_408_2022\/ref-29","doi-asserted-by":"publisher","first-page":"1035","DOI":"10.1007\/s10103-012-1185-1","article-title":"Effectiveness of a 308-nm excimer laser in treatment of vitiligo: A review","volume":"28","author":"Alhowaish","year":"2013","journal-title":"Lasers Med Sci"},{"key":"10.25259\/IJDVL_408_2022\/ref-30","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1001\/archderm.138.12.1613","article-title":"Treatment of vitiligo with the 308-nm xenon chloride laser","volume":"138","author":"Balt\u00e1s","year":"2002","journal-title":"Arch Dermatol"}],"container-title":["Indian Journal of Dermatology, Venereology and Leprology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ijdvl.com\/retrospective-analysis-of-ultrathin-skin-grafting-over-carbon-dioxide-ablated-lesions-supplemented-with-excimer-lamp-308-nm-therapy-in-stable-vitiligo\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ijdvl.com\/retrospective-analysis-of-ultrathin-skin-grafting-over-carbon-dioxide-ablated-lesions-supplemented-with-excimer-lamp-308-nm-therapy-in-stable-vitiligo\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,21]],"date-time":"2024-02-21T06:30:31Z","timestamp":1708497031000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ijdvl.com\/retrospective-analysis-of-ultrathin-skin-grafting-over-carbon-dioxide-ablated-lesions-supplemented-with-excimer-lamp-308-nm-therapy-in-stable-vitiligo\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,3]]},"references-count":30,"alternative-id":["10.25259\/IJDVL_408_2022"],"URL":"https:\/\/doi.org\/10.25259\/ijdvl_408_2022","relation":{},"ISSN":["0973-3922","0378-6323"],"issn-type":[{"value":"0973-3922","type":"electronic"},{"value":"0378-6323","type":"print"}],"subject":[],"published":{"date-parts":[[2023,5,3]]},"article-number":"150"}}