{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T16:15:57Z","timestamp":1790957757971,"version":"4.1.0"},"reference-count":15,"publisher":"Scientific Scholar","content-domain":{"domain":["ijdvl.com"],"crossmark-restriction":true},"short-container-title":["IJDVL"],"abstract":"\nBackground<\/jats:title>\nPsoriasis is a chronic inflammatory disease that presents as scaly patches on the skin that affects about 3% of the world's population. Adherence to treatment and discrimination against people are common problems, adversely impacts quality of life.<\/jats:p>\n<\/jats:sec>\n\nObjectives<\/jats:title>\nThe aim of this study was to investigate the use of medicinal plants as therapeutic adjuvants in the treatment of plaque psoriasis through a systematic review and meta-analysis.<\/jats:p>\n<\/jats:sec>\n\nMethods<\/jats:title>\nA systematic review and meta-analysis of randomized controlled trials in patients with plaque psoriasis was carried out, comparing the efficacy of herbal treatments alone or in association with other therapies. The search was performed in the databases of The Cochrane Library, Lilacs, Medline via PubMed and Embase, only including studies published from 2016 to 2020.The certainty of evidence was assessed using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) framework. A systematic review and meta-analysis of randomized controlled trials (RCT) in patients with plaque psoriasis was carried out, comparing the efficacy of herbal treatments alone or in association with other therapies. We comprehensively searched the MEDLINE, Embase, Lilacs and Cochrane Library databases, only including studies published from 2016 to 2020. The certainty of evidence was assessed using the GRADE approach.<\/jats:p>\n<\/jats:sec>\n\nResults<\/jats:title>\nOut of 2,268 articles evaluated, only seven RCT were eligible for final analysis. Five of these studies evidenced low risk of bias and a high level of evidence.<\/jats:p>\n<\/jats:sec>\n\nLimitations<\/jats:title>\nFew RCT of medicinal plants.<\/jats:p>\n<\/jats:sec>\n\nConclusion<\/jats:title>\nThis meta-analysis indicates that medicinal plants may be used as topical or oral products, either alone or combined with other forms of treatment. These products have the potential to greatly improve the quality of life of the patient.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/ijdvl_46_2022","type":"journal-article","created":{"date-parts":[[2022,11,21]],"date-time":"2022-11-21T11:32:05Z","timestamp":1669030325000},"page":"543-548","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["The use of medicinal plants for the treatment of psoriasis: A systematic review and meta-analysis"],"prefix":"10.25259","volume":"89","author":[{"given":"Gisele MS","family":"Gon\u00e7alves","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laina R","family":"Wenceslau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose Alexandre","family":"Mendon\u00e7a","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2022,11,18]]},"reference":[{"key":"10.25259\/IJDVL_46_2022\/ref-1","first-page":"246","article-title":"Perfil epidemiol\u00f3gico e qualidade de vida na psor\u00edase","volume":"15","author":"Silveira","year":"2017","journal-title":"Ver Soc Bras Clin Med"},{"key":"10.25259\/IJDVL_46_2022\/ref-2","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1038\/s41423-020-0519-3","article-title":"\u201cAutoinflammatory psoriasis\u201d\u2014genetics and biology of pustular psoriasis","volume":"18","author":"Uppala","year":"2020","journal-title":"Cell Mol Immunol"},{"key":"10.25259\/IJDVL_46_2022\/ref-3","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-019-7778-x","article-title":"Analyzing the value of an educational program for psoriasis patients: A prospective controlled pilot 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