{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T22:36:28Z","timestamp":1785796588777,"version":"3.56.0"},"reference-count":32,"publisher":"Scientific Scholar","content-domain":{"domain":["ijdvl.com"],"crossmark-restriction":true},"short-container-title":["IJDVL"],"abstract":"<jats:sec id=\"st1\">\n<jats:title>Background:<\/jats:title>\n<jats:p>Several epidemiological studies have shown that psoriasis increases the risk of developing atrial fibrillation but evidence of this is still scarce.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st2\">\n<jats:title>Aims:<\/jats:title>\n<jats:p>Our objective was to systematically review, synthesise and critique the epidemiological studies that provided information about the relationship between psoriasis and atrial fibrillation risk.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st3\">\n<jats:title>Methods:<\/jats:title>\n<jats:p>We searched through PubMed, EMBASE and the bibliographies for articles published between 1 January 2000, and 1 November 2017, that reported on the association between psoriasis and atrial fibrillation. All abstracts, full-text articles and sources were reviewed with duplicate data excluded. Summary relative risks (RRs) with 95% CI were pooled using a random effects model.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st4\">\n<jats:title>Results:<\/jats:title>\n<jats:p>We identified 252 articles, of these eight unique abstracts underwent full-text review. We finally selected six out of these eight studies comprising 11,187 atrial fibrillation patients. The overall pooled relative risk (RR) of atrial fibrillation was 1.39 (95% CI: 1.257\u20131.523, <jats:italic>P<\/jats:italic> &lt; 0.0001) with significant heterogeneity (I<jats:sup>2<\/jats:sup> = 80.316, Q = 45.723, \u03c4<jats:sup>2<\/jats:sup> = 0.017, <jats:italic>P<\/jats:italic> &lt; 0.0001) for the random effects model. In subgroup analysis, the greater risk was found in studies from North America, RR 1.482 (95% CI: 1.119\u20131.964, <jats:italic>P<\/jats:italic> &lt; 0.05), whereas a moderate risk was observed in studies from Europe RR 1.43 (95% CI: 1.269\u20131.628, <jats:italic>P<\/jats:italic> &lt; 0.0001).<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st5\">\n<jats:title>Limitations:<\/jats:title>\n<jats:p>We were only able to include six studies with 11,178 atrial fibrillation patients, because only a few such studies have been published.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st6\">\n<jats:title>Conclusion:<\/jats:title>\n<jats:p>Our results showed that psoriasis is significantly associated with an increased risk of developing atrial fibrillation. Therefore, physicians should monitor patient\u2019s physical condition on a timely basis.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/ijdvl_608_18","type":"journal-article","created":{"date-parts":[[2022,7,30]],"date-time":"2022-07-30T06:57:40Z","timestamp":1659164260000},"page":"18-24","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Increased risk of atrial fibrillation in patients with psoriasis: A meta-analysis of observational studies"],"prefix":"10.25259","volume":"89","author":[{"given":"Hsuan Chia","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tahmina Nasrin","family":"Poly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Md. Mohaimenul","family":"Islam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno Andreas","family":"Walther","sequence":"additional","affiliation":[{"name":"Alfred-Wegener-Institut Helmholtz-Zentrum f\u00fcr Polar-und Meeresforschung, Bremerhaven, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chieh-Chen","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Exercise and Health Promotion, College of Kinesiology and Health, Chinese Culture University, Taipei, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2022,7,30]]},"reference":[{"key":"10.25259\/IJDVL_608_18\/ref-1","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1038\/jid.2012.339","article-title":"Global epidemiology of psoriasis: a systematic review of incidence and prevalence","volume":"133","author":"Parisi","year":"2013","journal-title":"Journal 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