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While the cornoid lamella is the classical histopathologic feature, dermoscopy and reflectance confocal microscopy make the diagnosis clearer. Development of malignancy in a few variants is a concern. Linear, disseminated superficial actinic and giant lesions are most prone to developing malignancies. Bowen\u2019s disease, squamous cell carcinoma, basal cell carcinoma and even melanoma have been reported in cases of long-standing porokeratosis. Newer modalities of therapy such as photodynamic therapy, ingenol mebutate and HMGCoA inhibitors may play a role in the future.<\/jats:p>","DOI":"10.25259\/ijdvl_806_20","type":"journal-article","created":{"date-parts":[[2021,11,18]],"date-time":"2021-11-18T01:13:34Z","timestamp":1637198014000},"page":"291-299","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":47,"title":["Porokeratosis: An enigma beginning to unravel"],"prefix":"10.25259","volume":"88","author":[{"given":"Anupam","family":"Das","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Biju","family":"Vasudevan","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Armed Forces Medical College, Pune, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ankur","family":"Talwar","sequence":"additional","affiliation":[{"name":"Talwar Skin Centre, Lucknow, Uttar Pradesh, 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