{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T17:20:52Z","timestamp":1787505652560,"version":"build-2736575974"},"reference-count":21,"publisher":"Scientific Scholar","content-domain":{"domain":["ijdvl.com"],"crossmark-restriction":true},"short-container-title":["IJDVL"],"abstract":"\n Background:<\/jats:title>\n Lichen planus pigmentosus can have a negative impact on the quality of life; however, this has not been studied in detail.<\/jats:p>\n <\/jats:sec>\n \n Objectives:<\/jats:title>\n To study the quality of life in patients with lichen planus pigmentosus and compare it with patients with vitiligo and melasma.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n \n This was a cross-sectional study conducted in a tertiary-care center in north India from January 2018 to May 2019. Patients \u2265 18 years of age with lichen planus pigmentosus (\n n<\/jats:italic>\n = 125), vitiligo (\n n<\/jats:italic>\n = 113) and melasma (\n n<\/jats:italic>\n = 121) completed the Dermatology Life Quality Index (DLQI) questionnaire and answered a global question on the effect of disease on their lives. In addition, patients with vitiligo completed the Vitiligo Impact Scale (VIS)-22 questionnaire, while those with lichen planus pigmentosus and melasma filled a modified version of VIS-22.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n The mean DLQI scores in patients with lichen planus pigmentosus, vitiligo and melasma were 10.9 \u00b1 5.95, 9.73 \u00b1 6.51 and 8.39 \u00b1 5.92, respectively, the difference being statistically significant only between lichen planus pigmentosus and melasma (\n P<\/jats:italic>\n < 0.001). The corresponding mean modified VIS-22\/VIS-22 scores were 26.82 \u00b1 11.89, 25.82 \u00b1 14.03 and 18.87 \u00b1 11.84, respectively. This difference was statistically significant between lichen planus pigmentosus and melasma, and between vitiligo and melasma (\n P<\/jats:italic>\n < 0.001 for both). As compared to vitiligo, patients with lichen planus pigmentosus had a significantly greater impact on \u201csymptoms and feelings\u201d domain (\n P<\/jats:italic>\n < 0.001) on DLQI, and on \u201csocial interactions\u201d (\n P<\/jats:italic>\n = 0.02) and \u201cdepression\u201d (\n P<\/jats:italic>\n = 0.04) domains on VIS-22. As compared to melasma, patients with lichen planus pigmentosus had significantly higher scores for \u201csymptoms and feelings,\u201d \u201cdaily activities,\u201d \u201cleisure\u201d and \u201cwork and school\u201d domains of DLQI, and all domains of VIS-22. Female gender was more associated with impairment in quality of life in patients with lichen planus pigmentosus, while lower education, marriage, younger age and increasing disease duration showed a directional trend.\n <\/jats:p>\n <\/jats:sec>\n \n Limitations:<\/jats:title>\n Use of DLQI and modified version of VIS-22 scales in the absence of a pigmentary disease-specific quality-of-life instrument.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Patients with lichen planus pigmentosus have a significantly impaired quality of life. The psychosocial burden of lichen planus pigmentosus is quantitatively similar to that of vitiligo, but significantly greater than melasma.<\/jats:p>\n <\/jats:sec>","DOI":"10.25259\/ijdvl_877_19","type":"journal-article","created":{"date-parts":[[2021,4,23]],"date-time":"2021-04-23T06:54:55Z","timestamp":1619160895000},"page":"341-347","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Psychosocial burden of lichen planus pigmentosus is similar to vitiligo, but greater than melasma: A cross-sectional study from a tertiary-care center in north India"],"prefix":"10.25259","volume":"87","author":[{"given":"Vishal","family":"Gupta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepika","family":"Yadav","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sujata","family":"Satapathy","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashish","family":"Upadhyay","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, All India Institute of Medical Sciences, New Delhi, 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