{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T18:23:40Z","timestamp":1770056620644,"version":"3.49.0"},"reference-count":25,"publisher":"Global Health and Education Projects, Inc","content-domain":{"domain":["mchandaids.org"],"crossmark-restriction":true},"short-container-title":["IJMA"],"abstract":"<jats:sec id=\"st1\">\n                    <jats:title>Background and Objective:<\/jats:title>\n                    <jats:p>Sickle cell disease is a neglected inherited condition that affects the hemoglobin in red blood cells and impacts at least 2% of the West African population. This hemoglobinopathy presents with high mobility and mortality as a result of infections and vaso-occlusive pain crises as a result of structural abnormality of the red blood, making it fragile and rigid. The objective of our study was to describe the oral health status of sickle cell patients in Yaound\u00e9 Central Hospital, Cameroon.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"st2\">\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A descriptive cross-sectional study was carried out in the hematology unit of the Yaound\u00e9 Central Hospital from June to October 2022.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"st3\">\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A total of 63 patients, made up of 41 (65%) males and 22 (35%) females, were recruited in the study. The majority, 60 (95%), consumed sugary foods, while 43 (68%) brushed their teeth before meals, and 27 (43%) brushed their teeth once a day. A third, 24 (38%), presented with pallor of the palatal mucosa, and 24 (74.6%) had dental caries. The mean decayed, missing, and filled teeth index of this population was 2.6 (moderate) and 11 (17.5%) periodontitis. Less than a third, 17 (26.9%) of the patients had been to a dentist, 26 (41.3%) did not see it necessary to consult a dentist, while 23 (37%) thought that oral conditions are not serious. Two-thirds, 38 (60.5%), did not receive any treatment for caries. Tooth extraction 18 (27.9%) was the most common treatment given, 5 (7%) conservative treatment, and no treatment was administered for periodontitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"st4\">\n                    <jats:title>Conclusion and Global Health Implications:<\/jats:title>\n                    <jats:p>There was a high prevalence of periodontal diseases, moderate levels of dental caries, and elevated prevalence of oral mucosal lesions like tonsillar hypertrophy, pallor of the palate, lingual mycosis inflammation, and mucositis among sickle cell patients. The poor oral health-seeking behavior of the patients and poor oral hygiene practices might be responsible for the high burden of carious and periodontal diseases.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.25259\/ijma_28_2024","type":"journal-article","created":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T01:06:09Z","timestamp":1747184769000},"page":"e010","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Oral Health Status of People with Sickle Cell Disease at a Major Hospital in Cameroon"],"prefix":"10.21106","volume":"14","author":[{"given":"Ashu Michael","family":"Agbor","sequence":"first","affiliation":[{"name":"Department of Oral Health\/Dentistry, Universit\u00e9 des Montagnes Dental School, Bangangte, Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kepwa Florence","family":"Mekendja","sequence":"additional","affiliation":[{"name":"Department of Oral Health\/Dentistry, Universit\u00e9 des Montagnes Dental School, Bangangte, Cameroon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Blek","family":"Che","sequence":"additional","affiliation":[{"name":"Department of Community Oral Health, University of the Western Cape, Cape Town, Republic of South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sudeshni","family":"Naidoo","sequence":"additional","affiliation":[{"name":"Department of Community Oral Health, University of the Western Cape, Cape Town, Republic of South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"8847","published-online":{"date-parts":[[2025,5,14]]},"reference":[{"key":"10.25259\/IJMA_28_2024\/ref-1","article-title":"Regional Committee for Africa, 56: Sickle Cell Disease in the African Region: Current Situation and Prospects: Report of the Director-General","author":"World Health Organization","year":"2006"},{"issue":"1","key":"10.25259\/IJMA_28_2024\/ref-2","first-page":"6","article-title":"Epidemiology of sickle cell disease: Clinics in mother and child health","volume":"1","author":"Owono","year":"2004"},{"key":"10.25259\/IJMA_28_2024\/ref-3","first-page":"1","volume-title":"Sickle cell anemia","author":"Labe","year":"2003"},{"key":"10.25259\/IJMA_28_2024\/ref-5","first-page":"704","article-title":"Inherited haemoglobin disorders: An increasing global health problem","volume":"79","author":"Weatherall","year":"2001","journal-title":"Bull World Health Organ"},{"key":"10.25259\/IJMA_28_2024\/ref-6","first-page":"1543","article-title":"Diagnosis and screening of sickle cell disease","volume":"54","author":"Wajcman","year":"2004","journal-title":"Rev Prat"},{"key":"10.25259\/IJMA_28_2024\/ref-7","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1186\/s12913-021-06286-7","article-title":"Improvement of SCD morbimortality in children: Experience in a remote area of an African country","volume":"21","author":"Mbiya","year":"2021","journal-title":"BMC Health Serv Res"},{"issue":"4","key":"10.25259\/IJMA_28_2024\/ref-8","first-page":"360","article-title":"Reasons for late dental consultations at the central hospital of yaound\u00e9. Cameroon\"","volume":"17","author":"Agbor","year":"2018","journal-title":"EC Dent Sci"},{"issue":"7","key":"10.25259\/IJMA_28_2024\/ref-9","doi-asserted-by":"publisher","first-page":"154","DOI":"10.4081\/jphia.2023.2223","article-title":"Methods of payment for oral health care in Yaound\u00e9","volume":"14","author":"Agbor","year":"2023","journal-title":"J Public Health Afr"},{"issue":"1","key":"10.25259\/IJMA_28_2024\/ref-10","doi-asserted-by":"publisher","first-page":"1","DOI":"10.24018\/ejdent.2020.1.1.1","article-title":"Oral health practices and status of 12-year-old pupils in the western region of Cameroon","volume":"1","author":"Agbor","year":"2020","journal-title":"Eur J Dent Oral Health"},{"key":"10.25259\/IJMA_28_2024\/ref-11","doi-asserted-by":"publisher","first-page":"121","DOI":"10.3109\/00016356408993968","article-title":"Periodontal disease in pregnancy. II. Correlation between oral hygiene and periodontal condition","volume":"22","author":"Silness","year":"1964","journal-title":"Acta Odontol Scand"},{"key":"10.25259\/IJMA_28_2024\/ref-12","doi-asserted-by":"publisher","first-page":"S398","DOI":"10.1016\/j.amepre.2011.09.013","article-title":"Sickle cell disease in Africa: A neglected cause of early childhood mortality","volume":"41","author":"Grosse","year":"2011","journal-title":"Am J Prev Med"},{"key":"10.25259\/IJMA_28_2024\/ref-13","article-title":"Management of haemoglobin disorders-report of joint WHO-TIF meeting","author":"World Health Organization","year":"2006"},{"key":"10.25259\/IJMA_28_2024\/ref-14","doi-asserted-by":"publisher","first-page":"85","DOI":"10.11604\/pamj.2019.34.85.16432","article-title":"A cross sectional study of growth of children with sickle cell disease, aged 2 to 5 years in Yaound\u00e9, Cameroon","volume":"34","author":"Ngo Um","year":"2019","journal-title":"Pan Afr Med J"},{"key":"10.25259\/IJMA_28_2024\/ref-15","doi-asserted-by":"publisher","first-page":"140","DOI":"10.3389\/fmolb.2019.00140","article-title":"Gender-related differences in sickle cell disease in a pediatric cohort: A single-center retrospective study","volume":"6","author":"Ceglie","year":"2019","journal-title":"Front Mol Biosci"},{"issue":"3","key":"10.25259\/IJMA_28_2024\/ref-16","doi-asserted-by":"publisher","first-page":"179","DOI":"10.5144\/0256-4947.2004.179","article-title":"Differences between males and females in adult sickle cell pain crisis in eastern Saudi Arabia","volume":"24","author":"Udezue","year":"2004","journal-title":"Ann Saudi Med"},{"issue":"1","key":"10.25259\/IJMA_28_2024\/ref-17","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1016\/j.sdentj.2014.08.003","article-title":"The association between dental and periodontal diseases and sickle cell disease. A pilot case-control study","volume":"27","author":"Al-Alawi","year":"2015","journal-title":"Saudi Dent J"},{"key":"10.25259\/IJMA_28_2024\/ref-18","first-page":"23","article-title":"Oral health status of children with sickle cells in Kinshasa, DR Congo","volume":"14","author":"Kowe","year":"2022","journal-title":"Rom J Oral Rehabil"},{"issue":"9","key":"10.25259\/IJMA_28_2024\/ref-19","doi-asserted-by":"publisher","first-page":"672","DOI":"10.1177\/000331978603700909","article-title":"Oral and dental complications of sickle cell disease in Nigerians","volume":"37","author":"Okafor","year":"1986","journal-title":"Angiology"},{"issue":"2","key":"10.25259\/IJMA_28_2024\/ref-20","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1111\/j.1600-0609.1988.tb00813.x","article-title":"Unexplained lymphadenopathy in sickle cell disease","volume":"40","author":"Keidan","year":"1988","journal-title":"Eur J Haematol"},{"key":"10.25259\/IJMA_28_2024\/ref-21","doi-asserted-by":"publisher","first-page":"e022","DOI":"10.25259\/IJMA_7_2024","article-title":"Oral manifestations of HIV infection and dental health needs of children with HIV attending HIV treatment clinics in Western Cameroon","volume":"13","author":"Agbor","year":"2024","journal-title":"Int J MCH AIDS"},{"key":"10.25259\/IJMA_28_2024\/ref-22","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1186\/s12903-015-0052-4","article-title":"Caries prevalence and impact on oral health-related quality of life in children with sickle cell disease: Cross-sectional study","volume":"15","author":"Fernandes","year":"2015","journal-title":"BMC Oral Health"},{"key":"10.25259\/IJMA_28_2024\/ref-23","doi-asserted-by":"crossref","first-page":"53","DOI":"10.4103\/2231-6027.171156","article-title":"Dental and periodontal health status of Beta thalassemia major and sickle cell anemic patients: A comparative study","volume":"5","author":"Singh","year":"2013","journal-title":"J Int Oral Health"},{"issue":"1","key":"10.25259\/IJMA_28_2024\/ref-24","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1186\/s12903-018-0629-9","article-title":"Association between sickle cell disease and the oral health condition of children and adolescents","volume":"18","author":"Brand\u00e3o","year":"2018","journal-title":"BMC Oral Health"},{"key":"10.25259\/IJMA_28_2024\/ref-25","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1016\/j.archoralbio.2012.11.006","article-title":"Serum cytokine profile among Brazilian children of African descent with periodontal inflammation and sickle cell anemia","volume":"58","author":"Veiga","year":"2013","journal-title":"Arch Oral Biol"},{"key":"10.25259\/IJMA_28_2024\/ref-26","doi-asserted-by":"publisher","first-page":"1","DOI":"10.9734\/BJMMR\/2017\/30968","article-title":"Management of odontogenic abscess in patients with sickle cell anemia: 5 case reports","volume":"20","author":"Mutombo","year":"2017","journal-title":"Br J Med Med Res"}],"container-title":["International Journal of Maternal and Child Health and AIDS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/mchandaids.org\/oral-health-status-of-people-with-sickle-cell-disease-at-a-major-hospital-in-cameroon","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/mchandaids.org\/oral-health-status-of-people-with-sickle-cell-disease-at-a-major-hospital-in-cameroon","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T07:41:11Z","timestamp":1770018071000},"score":1,"resource":{"primary":{"URL":"https:\/\/mchandaids.org\/index.php\/ijma\/article\/view\/20"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,14]]},"references-count":25,"alternative-id":["10.25259\/IJMA_28_2024"],"URL":"https:\/\/doi.org\/10.25259\/ijma_28_2024","relation":{},"ISSN":["2161-864X","2161-8674"],"issn-type":[{"value":"2161-864X","type":"electronic"},{"value":"2161-8674","type":"print"}],"subject":[],"published":{"date-parts":[[2025,5,14]]},"article-number":"e010"}}