{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T04:05:18Z","timestamp":1793592318747,"version":"4.5.0"},"reference-count":25,"publisher":"Scientific Scholar","content-domain":{"domain":["ijmr.org.in"],"crossmark-restriction":true},"short-container-title":["Indian J Med Res"],"abstract":"\n Background & objectives<\/jats:title>\n Non-alcoholic fatty liver disease (NAFLD) is an emerging public health issue and affects 20\u201330 per cent of the general population globally and 9\u201353 per cent in India. We aimed to estimate the prevalence of NAFLD and associated risk factors among adults at high risk for NAFLD (\u226530 yr) in Puducherry.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n A community-based cross-sectional study was conducted among 350 adults at high risk for NAFLD (simple random sampling) in a rural area of Puducherry. Clinical assessment, and blood investigations (liver function tests, lipid profile) were performed. NAFLD was diagnosed using the fatty liver index and risk stratification for advanced liver fibrosis by using the FIB-4 score. The indeterminate\/high-risk participants underwent vibration controlled transient elastography (VCTE). Prevalence of NAFLD [proportions with 95 per cent confidence interval (CI)] and risk factors associated with NAFLD (multivariable regression) were reported.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Prevalence of NAFLD among adults at high risk was 22.8 per cent (95% CI:18.7% \u201327.5%); and higher among men (35.2%), those with diabetes mellitus (33.3%) and obesity (40.2%). Male sex, diabetes mellitus and elevated alanine transferase were significantly associated with high risk of NAFLD.<\/jats:p>\n <\/jats:sec>\n \n Interpretation & conclusions<\/jats:title>\n One in four screened adults had NAFLD, increasing to one in two among those with comorbidities.<\/jats:p>\n <\/jats:sec>","DOI":"10.25259\/ijmr_1634_2025","type":"journal-article","created":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T17:34:34Z","timestamp":1769880874000},"page":"786-791","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Screening for non-alcoholic fatty liver disease (NAFLD) among adults in Puducherry, India: A community-based cross-sectional study"],"prefix":"10.25259","volume":"162","author":[{"given":"Divya","family":"Harshini","sequence":"first","affiliation":[{"name":"Department of Community Medicine, Pondicherry Institute of Medical Sciences, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Subitha","family":"Lakshminarayanan","sequence":"additional","affiliation":[{"name":"Department of Preventive and Social Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mukta","family":"Wyawahare","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Balasubramaniyan","family":"Vairappan","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramkumar","family":"Govindarajalou","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2026,1,31]]},"reference":[{"key":"10.25259\/IJMR_1634_2025\/ref-1","first-page":"167","article-title":"Pathogenesis and prevention of hepatic steatosis","volume":"11","author":"Nassir","year":"2015","journal-title":"Gastroenterol Hepatol"},{"key":"10.25259\/IJMR_1634_2025\/ref-2","doi-asserted-by":"publisher","first-page":"147","DOI":"10.15386\/cjmed-993","article-title":"Non-alcoholic fatty liver disease: an update on diagnosis","volume":"91","author":"Dumitrascu","year":"2018","journal-title":"Clujul Med"},{"key":"10.25259\/IJMR_1634_2025\/ref-3","doi-asserted-by":"publisher","first-page":"794","DOI":"10.1111\/j.1440-1746.2007.04952.x","article-title":"What are the risk factors and settings for non-alcoholic fatty liver disease in 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