{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T10:59:04Z","timestamp":1771066744955,"version":"3.50.1"},"reference-count":37,"publisher":"Scientific Scholar","content-domain":{"domain":["ijmr.org.in"],"crossmark-restriction":true},"short-container-title":["Indian J Med Res"],"abstract":"<jats:sec>\n<jats:title>Background &amp; objectives<\/jats:title>\n<jats:p>Cancer contributes to decreasing life expectancy, especially in low- and middle- income countries (LMIC) and countries in transition where resources for diagnosis and care are limited. As the world population is ageing, and by 2050, two-thirds of the population in LMIC will be elderly, the greater impact of cancer on the expectation of life in years at a given age of an adult will be seen in these countries.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>Estimated cancer mortality for older adults (60 yr or above) was estimated using statistics available on Globocan 2020 platform (<jats:italic>gco.iarc.fr<\/jats:italic>). This platform provided the number of deaths and age\u2010standardized truncated mortality rates (per 100,000) by sex and continent. We calculated the projected cancer deaths in 2040 by applying the projection model, considering a stable rate.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>Globally, with an estimated 7.5 million deaths, cancer deaths in older population represented a total of 71.2 per cent of all cancer-related deaths. The truncated age-adjusted mortality rate among the older population (both sexes) was estimated as 615.1 deaths per 100,000 and the mortality rate was 62.6 per cent higher in elderly (60 yr or above) males as compared to elderly females. The overall future cancer death among the elderly was estimated to increase from 7.05 to 12.7 million deaths, representing a total 80.2 per cent increase in deaths by 2040.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Interpretation &amp; conclusions<\/jats:title>\n<jats:p>The projected mortality increase will challenge existing healthcare systems, especially in lower or lower medium-income countries where resources are limited. Elderly patients are at an elevated risk of adverse outcomes due to the high prevalence of co-morbid conditions. Geriatric oncology will play an important role in the coming years to ensure the overall health and well-being of elderly patients, which needs to be supported by good stratified data on elderly cancer.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/ijmr_1671_23","type":"journal-article","created":{"date-parts":[[2024,10,18]],"date-time":"2024-10-18T07:18:41Z","timestamp":1729235921000},"page":"165-175","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Global variations in elderly cancer mortality pattern in 2020 &amp; prediction to 2040: A population-based study"],"prefix":"10.25259","volume":"160","author":[{"given":"Manoj","family":"Kalita","sequence":"first","affiliation":[{"name":"ICMR-Centre for Ageing & Mental Health, Kolkata, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Devaraja","sequence":"additional","affiliation":[{"name":"ICMR-Centre for Ageing & Mental Health, Kolkata, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Indranil","family":"Saha","sequence":"additional","affiliation":[{"name":"ICMR-Centre for Ageing & Mental Health, Kolkata, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amit","family":"Chakrabarti","sequence":"additional","affiliation":[{"name":"ICMR-Centre for Ageing & Mental Health, Kolkata, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2024,10,19]]},"reference":[{"key":"10.25259\/ijmr_1671_23\/ref-1","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1016\/S0140-6736(22)01438-6","article-title":"The global burden of cancer attributable to risk factors, 2010-19: A systematic analysis for the global burden of disease study 2019","volume":"400","author":"Tran","year":"2022","journal-title":"Lancet"},{"key":"10.25259\/ijmr_1671_23\/ref-2","doi-asserted-by":"publisher","first-page":"209","DOI":"10.3322\/caac.21660","article-title":"Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"71","author":"Sung","year":"2021","journal-title":"CA Cancer J Clin"},{"key":"10.25259\/ijmr_1671_23\/ref-3","volume-title":"Global Health Estimates 2016: Deaths by cause, age, sex, by country and by region, 2000-2016","author":"LI","year":"2018"},{"key":"10.25259\/ijmr_1671_23\/ref-4","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1002\/ijc.31664","article-title":"Global cancer incidence in older adults, 2012 and 2035: A population\u2010based study","volume":"144","author":"Pilleron","year":"2019","journal-title":"Int J Cancer"},{"key":"10.25259\/ijmr_1671_23\/ref-5","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1007\/s12254-020-00657-2","article-title":"Prevalence of comorbidities in elderly cancer patients","volume":"14","author":"Wenkstetten-Holub","year":"2021","journal-title":"Memo"},{"key":"10.25259\/ijmr_1671_23\/ref-6","doi-asserted-by":"publisher","first-page":"4868","DOI":"10.21037\/apm-20-2439","article-title":"Refusal of medical treatment by older adults with cancer: a systematic review","volume":"10","author":"Dias","year":"2021","journal-title":"Ann Palliat Med"},{"key":"10.25259\/ijmr_1671_23\/ref-7","doi-asserted-by":"publisher","first-page":"452","DOI":"10.3322\/caac.21577","article-title":"Cancer statistics for adults aged 85 years and older, 2019","volume":"69","author":"DeSantis","year":"2019","journal-title":"CA Cancer J Clin"},{"key":"10.25259\/ijmr_1671_23\/ref-12","volume-title":"Cancer incidence in five continents: A technical report","year":"1966"},{"key":"10.25259\/ijmr_1671_23\/ref-13","doi-asserted-by":"publisher","first-page":"1391","DOI":"10.1016\/S0140-6736(17)32513-8","article-title":"Alleviating the access abyss in palliative care and pain relief-an imperative of universal health coverage: The Lancet Commission report","volume":"391","author":"Knaul","year":"2018","journal-title":"Lancet"},{"key":"10.25259\/ijmr_1671_23\/ref-14","doi-asserted-by":"publisher","first-page":"480","DOI":"10.1177\/107327481502200414","article-title":"Palliative care in older patients with cancer","volume":"22","author":"Balducci","year":"2015","journal-title":"Cancer Control"},{"key":"10.25259\/ijmr_1671_23\/ref-15","doi-asserted-by":"publisher","first-page":"1458","DOI":"10.1200\/JCO.2010.31.6695","article-title":"Association of cancer with geriatric syndromes in older medicare beneficiaries","volume":"29","author":"Mohile","year":"2011","journal-title":"J Clin Oncol"},{"key":"10.25259\/ijmr_1671_23\/ref-16","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1016\/s0959-8049(01)00267-2","article-title":"Cancer burden in the year 2000. 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