{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T18:17:04Z","timestamp":1773339424425,"version":"3.50.1"},"reference-count":22,"publisher":"Scientific Scholar","content-domain":{"domain":["ijmr.org.in"],"crossmark-restriction":true},"short-container-title":["Indian J Med Res"],"abstract":"<jats:sec>\n                    <jats:title>Background and objectives<\/jats:title>\n                    <jats:p>Despite therapeutic advancements, patients with drug-resistant TB (DR-TB) experience substantial psychosocial challenges that adversely affect treatment adherence and outcomes. Limited research has explored these psychosocial barriers. This study aimed to explore the psychosocial challenges encountered by DR-TB patients from diagnosis through treatment completion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A cross-sectional qualitative study was conducted in the department of Pulmonary Medicine at a tertiary care hospital in eastern India from November to December 2023. Using criterion sampling, 20 DR-TB patients who had successfully completed treatment were recruited. Semi-structured, face-to-face interviews were conducted in Hindi, audio-recorded, transcribed verbatim, and thematically analysed using QDA Miner Lite software following Braun and Clarke\u2019s six-step framework.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Six major themes emerged:\n                      <jats:italic>(i)<\/jats:italic>\n                      Diagnosis-related challenges such as delays, lack of awareness, and misguidance;\n                      <jats:italic>(ii)<\/jats:italic>\n                      Physical and mental health impact, including severe drug-related side effects leading to distress and suicidal thoughts;\n                      <jats:italic>(iii)<\/jats:italic>\n                      Emotional instability, marked by fear, anxiety, and hopelessness;\n                      <jats:italic>(iv)<\/jats:italic>\n                      Family isolation and disruption of social relationships due to stigma and misconceptions;\n                      <jats:italic>(v)<\/jats:italic>\n                      Lack of social support, resulting in discrimination and reduced self-esteem; and\n                      <jats:italic>(vi)<\/jats:italic>\n                      Financial burden, including job loss, treatment-related costs, and debt.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interpretation and conclusions<\/jats:title>\n                    <jats:p>Psychosocial barriers substantially influence treatment adherence and overall well-being among DR-TB patients. Integrating mental health services, strengthening counselling, addressing stigma, and providing financial assistance within the National TB Elimination Program (NTEP) are essential to improve patient support, adherence, and clinical outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.25259\/ijmr_1697_2025","type":"journal-article","created":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T16:26:09Z","timestamp":1772382369000},"page":"62-68","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Psychosocial challenges of drug-resistant tuberculosis: A qualitative study in Deoghar, Eastern India"],"prefix":"10.25259","volume":"163","author":[{"given":"Raja","family":"Babu","sequence":"first","affiliation":[{"name":"Department of Physiology, \u2020All India Institute of Medical Sciences, Deoghar, Jharkhand, 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