{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T12:24:59Z","timestamp":1774355099809,"version":"3.50.1"},"reference-count":73,"publisher":"Scientific Scholar","content-domain":{"domain":["ijmr.org.in"],"crossmark-restriction":true},"short-container-title":["Indian J Med Res"],"abstract":"<jats:p>\n                    Diabetes mellitus and cancer are growing global health concerns with a rising prevalence and substantial associated mortality. The study aims to find impact of diabetes mellitus in cancer. A narrative review was conducted by analysing evidence from various sources, including meta-analyses, systematic reviews, retrospective studies, database analyses, and cohort studies. The review explored the complex interplay between Diabetes Mellitus and cancer, like cancer incidence, oncology outcome\n                    <jats:bold>\n                      <jats:italic>i.e.<\/jats:italic>\n                    <\/jats:bold>\n                    , acute and late toxicities, treatment compliance, overall survival (OS), and quality of life (QoL). Diabetes mellitus increases the risk of developing cancer by 10%. Diabetic patients had higher infection rates [2.6%\u201352%, odds ratio (OR) 1.38\u20131.57], increased haematologic toxicity (13%\u201365.7%,\n                    <jats:italic>P<\/jats:italic>\n                    =0.004), and greater hospital admissions (17.2%\u201374.5%, OR 2.1,\n                    <jats:italic>P<\/jats:italic>\n                    &lt; 0.001). They received significantly lower cisplatin doses (18%\u201333% reduction), experienced more surgical delays [adjusted OR 1.16, 95% confidence interval (CI) 1.05\u20131.27], higher risk of flap failure (RR=1.83, 95% CI 1.18\u20132.85,\n                    <jats:italic>P<\/jats:italic>\n                    =0.007) and were less likely to undergo breast reconstruction (adjusted OR 0.48\u20130.54, 95% CI 0.24\u20131.00). Diabetes mellitus decreases local control by 10-20%, increases mortality by 27-98%, and decreases OS by 18-50% across various cancers. It increases late toxicity and negatively impacts QOL with a 1.3\u20132.7 times higher risk of grade \u22652 genitourinary and gastrointestinal toxicity in prostate cancer, a twofold increase in grade \u22653 radiation pneumonitis in lung cancer, and a 50% higher incidence of severe peripheral neuropathy in breast cancer, leading to delayed recovery and long-term morbidity. In patients receiving cancer directed therapy, diabetes mellitus increases acute and late toxicities, decreased local control and overall survival, and have poor quality of life.\n                  <\/jats:p>","DOI":"10.25259\/ijmr_1911_2025","type":"journal-article","created":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T13:00:44Z","timestamp":1773925244000},"page":"221-230","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of diabetes mellitus in cancer"],"prefix":"10.25259","volume":"163","author":[{"given":"Hadrian Noel","family":"Alexander F.","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology, St. John\u2019s Medical College and Hospital, Bengaluru, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandeep","family":"Muzumder","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, St. John\u2019s Medical College and Hospital, Bengaluru, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silpa","family":"Johnson","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, St. John\u2019s Medical College and Hospital, Bengaluru, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nirmala","family":"Srikantia","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, St. John\u2019s Medical College and Hospital, Bengaluru, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Avinash H.","family":"Udayashankara","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, St. John\u2019s Medical College and Hospital, Bengaluru, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Jayalekshmi","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, St. John\u2019s Medical College and Hospital, Bengaluru, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2026,3,19]]},"reference":[{"key":"10.25259\/IJMR_1911_2025\/ref-1","doi-asserted-by":"publisher","first-page":"107843","DOI":"10.1016\/j.diabres.2019.107843","article-title":"Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the international diabetes federation diabetes atlas, 9th edition","volume":"157","author":"Saeedi","year":"2019","journal-title":"Diabetes Res Clin Pract."},{"key":"10.25259\/IJMR_1911_2025\/ref-2","doi-asserted-by":"publisher","first-page":"800995","DOI":"10.3389\/fendo.2022.800995","article-title":"The relationship between diabetes mellitus and cancers and its underlying mechanisms","volume":"13","author":"Zhu","year":"2022","journal-title":"Front Endocrinol (Lausanne)."},{"key":"10.25259\/IJMR_1911_2025\/ref-3","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1017\/s0022172400005702","article-title":"The relation between the cancer and diabetes death\u2013rates","volume":"14","author":"Greenwood","year":"1914","journal-title":"J Hyg (Lond)."},{"key":"10.25259\/IJMR_1911_2025\/ref-4","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1111\/cas.12043","article-title":"Diabetes mellitus and cancer risk: Review of the epidemiological evidence","volume":"104","author":"Shikata","year":"2013","journal-title":"Cancer Sci."},{"key":"10.25259\/IJMR_1911_2025\/ref-5","doi-asserted-by":"publisher","first-page":"1639","DOI":"10.1002\/ijc.26165","article-title":"Increased risk of hepatocellular carcinoma in patients with diabetes mellitus: A systematic review and meta\u2010analysis of cohort studies","volume":"130","author":"Wang","year":"2012","journal-title":"Int J Cancer."},{"key":"10.25259\/IJMR_1911_2025\/ref-6","doi-asserted-by":"publisher","first-page":"1928","DOI":"10.1016\/j.ejca.2011.03.003","article-title":"Diabetes mellitus and risk of pancreatic cancer: A meta\u2013analysis of cohort studies","volume":"47","author":"Ben","year":"2011","journal-title":"Eur J Cancer."},{"key":"10.25259\/IJMR_1911_2025\/ref-7","doi-asserted-by":"publisher","first-page":"1127","DOI":"10.1097\/MEG.0b013e32834b8d73","article-title":"Diabetes mellitus and risk of gastric cancer: A systematic review and meta\u2013analysis of observational studies","volume":"23","author":"Ge","year":"2011","journal-title":"Eur J Gastroenterol Hepatol."},{"key":"10.25259\/IJMR_1911_2025\/ref-8","doi-asserted-by":"publisher","first-page":"863","DOI":"10.1007\/s10654-011-9617-y","article-title":"Diabetes mellitus and incidence and mortality of colorectal cancer: A systematic review and meta\u2013analysis of cohort studies","volume":"26","author":"Jiang","year":"2011","journal-title":"Eur J Epidemiol."},{"key":"10.25259\/IJMR_1911_2025\/ref-9","doi-asserted-by":"publisher","first-page":"1013","DOI":"10.1007\/s00125-011-2051-6","article-title":"Diabetes mellitus and incidence of kidney cancer: A meta\u2013analysis of cohort studies","volume":"54","author":"Larsson","year":"2011","journal-title":"Diabetologia."},{"key":"10.25259\/IJMR_1911_2025\/ref-10","doi-asserted-by":"publisher","first-page":"2819","DOI":"10.1007\/s00125-006-0468-0","article-title":"Diabetes mellitus and risk of bladder cancer: A meta\u2013analysis","volume":"49","author":"Larsson","year":"2006","journal-title":"Diabetologia."},{"key":"10.25259\/IJMR_1911_2025\/ref-11","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1002\/ijc.22717","article-title":"Diabetes mellitus and risk of breast cancer: A meta\u2010analysis","volume":"121","author":"Larsson","year":"2007","journal-title":"Intl Cancer."},{"key":"10.25259\/IJMR_1911_2025\/ref-12","doi-asserted-by":"publisher","first-page":"1365","DOI":"10.1007\/s00125-007-0681-5","article-title":"Diabetes mellitus and risk of endometrial cancer: A meta\u2013analysis","volume":"50","author":"Friberg","year":"2007","journal-title":"Diabetologia."},{"key":"10.25259\/IJMR_1911_2025\/ref-13","doi-asserted-by":"publisher","first-page":"g7607","DOI":"10.1136\/bmj.g7607","article-title":"Type 2 diabetes and cancer: Umbrella review of meta\u2013analyses of observational studies","volume":"350","author":"Tsilidis","year":"2015","journal-title":"BMJ."},{"key":"10.25259\/IJMR_1911_2025\/ref-14","doi-asserted-by":"publisher","first-page":"828","DOI":"10.3390\/curroncol31020061","article-title":"Acute diabetes\u2013related complications in patients receiving chemoradiotherapy for head and neck cancer","volume":"31","author":"Mellor","year":"2024","journal-title":"Curr Oncol."},{"key":"10.25259\/IJMR_1911_2025\/ref-15","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1038\/ncponc0062","article-title":"Therapy insight: Influence of type 2 diabetes on the development, treatment and outcomes of cancer","volume":"2","author":"Richardson","year":"2005","journal-title":"Nat Clin Pract Oncol."},{"key":"10.25259\/IJMR_1911_2025\/ref-16","doi-asserted-by":"publisher","first-page":"7702","DOI":"10.1038\/s41598-020-64844-1","article-title":"Impact of diabetes mellitus on head and neck cancer patients undergoing concurrent chemoradiotherapy","volume":"10","author":"Kuo","year":"2020","journal-title":"Sci Rep."},{"key":"10.25259\/IJMR_1911_2025\/ref-17","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1002\/ijc.34268","article-title":"Diabetes is associated with high risk of severe adverse events during chemotherapy for cancer patients: A single\u2010center study","volume":"152","author":"Mailliez","year":"2023","journal-title":"Int J Cancer."},{"key":"10.25259\/IJMR_1911_2025\/ref-18","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1177\/0194599815607852","article-title":"Impact of diabetes mellitus on head and neck cancer patients undergoing surgery","volume":"154","author":"Raikundalia","year":"2016","journal-title":"Otolaryngol Head Neck Surg."},{"key":"10.25259\/IJMR_1911_2025\/ref-19","doi-asserted-by":"publisher","first-page":"2170","DOI":"10.1200\/JCO.2008.17.5935","article-title":"Impact of diabetes mellitus on complications and outcomes of adjuvant chemotherapy in older patients with breast cancer","volume":"27","author":"Srokowski","year":"2009","journal-title":"J Clin Oncol."},{"key":"10.25259\/IJMR_1911_2025\/ref-20","doi-asserted-by":"publisher","first-page":"3031","DOI":"10.1002\/hed.26349","article-title":"Diabetes mellitus in major head and neck cancer surgery: Systematic review and meta\u2010analysis","volume":"42","author":"Caputo","year":"2020","journal-title":"Head Neck."},{"key":"10.25259\/IJMR_1911_2025\/ref-21","doi-asserted-by":"crossref","first-page":"e18553","DOI":"10.1200\/JCO.2020.38.15_suppl.e18553","article-title":"Optimal cumulative cisplatin dose for radio\u2013sensitization in locally advanced head and neck cancer","volume":"38","author":"Bhattacharjee","year":"2020","journal-title":"JCO."},{"key":"10.25259\/IJMR_1911_2025\/ref-22","doi-asserted-by":"publisher","first-page":"931","DOI":"10.2337\/dc09-1721","article-title":"Postoperative mortality in cancer patients with preexisting diabetes","volume":"33","author":"Barone","year":"2010","journal-title":"Diabetes Care."},{"key":"10.25259\/IJMR_1911_2025\/ref-23","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1007\/s10549-023-06915-1","article-title":"Impact of diabetes on surgery and radiotherapy for breast cancer","volume":"199","author":"Lawrenson","year":"2023","journal-title":"Breast Cancer Res Treat."},{"key":"10.25259\/IJMR_1911_2025\/ref-24","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1016\/s0360-3016(01)01690-x","article-title":"Randomized trial addressing risk features and time factors of surgery plus radiotherapy in advanced head\u2013and\u2013neck cancer","volume":"51","author":"Ang","year":"2001","journal-title":"Int J Radiat Oncol Biol Phys."},{"key":"10.25259\/IJMR_1911_2025\/ref-25","doi-asserted-by":"publisher","first-page":"677","DOI":"10.1007\/s12094-015-1417-5","article-title":"Compliance to radiation therapy of head and neck cancer patients and impact on treatment outcome","volume":"18","author":"Ferreira","year":"2016","journal-title":"Clin Transl Oncol."},{"key":"10.25259\/IJMR_1911_2025\/ref-26","doi-asserted-by":"publisher","first-page":"e196","DOI":"10.1016\/j.clnesp.2015.03.045","article-title":"Enteral nutrition in head and neck cancer patients treated with intensity\u2013modulated radiotherapy at a United Kingdom cancer centre","volume":"10","author":"Lewis","year":"2015","journal-title":"Clin Nutr ESPEN."},{"key":"10.25259\/IJMR_1911_2025\/ref-27","doi-asserted-by":"publisher","first-page":"e249548","DOI":"10.1001\/jamanetworkopen.2024.9548","article-title":"Preexisting diabetes and breast cancer treatment among low\u2013income women","volume":"7","author":"Bekele","year":"2024","journal-title":"JAMA Netw Open."},{"key":"10.25259\/IJMR_1911_2025\/ref-28","doi-asserted-by":"publisher","first-page":"1461","DOI":"10.1186\/s12885-024-13232-3","article-title":"The impact of diabetes mellitus on short and long term outcomes in patients with gastric cancer following radical surgery: A retrospective cohort study with propensity score matching","volume":"24","author":"Yu","year":"2024","journal-title":"BMC Cancer."},{"key":"10.25259\/IJMR_1911_2025\/ref-29","doi-asserted-by":"publisher","first-page":"2915","DOI":"10.1007\/s40618-024-02417-z","article-title":"Glycemic control and cancer outcomes association of medical oncology in oncologic patients with diabetes: An Italian (AIOM), Italian association of medical diabetologists (AMD), Italian society of diabetology (SID), Italian society of endocrinology (SIE), Italian society of pharmacology (SIF) multidisciplinary critical view","volume":"47","author":"Natalicchio","year":"2024","journal-title":"J Endocrinol Invest."},{"key":"10.25259\/IJMR_1911_2025\/ref-30","doi-asserted-by":"publisher","first-page":"2754","DOI":"10.1001\/jama.2008.824","article-title":"Long\u2013term all\u2013cause mortality in cancer patients with preexisting diabetes mellitus: A systematic review and meta\u2013analysis","volume":"300","author":"Barone","year":"2008","journal-title":"JAMA."},{"key":"10.25259\/IJMR_1911_2025\/ref-31","doi-asserted-by":"publisher","first-page":"e7981","DOI":"10.1097\/MD.0000000000007981","article-title":"The association between diabetes\/hyperglycemia and the prognosis of cervical cancer patients: A systematic review and meta\u2013analysis","volume":"96","author":"Chen","year":"2017","journal-title":"Medicine (Baltimore)."},{"key":"10.25259\/IJMR_1911_2025\/ref-32","doi-asserted-by":"publisher","first-page":"e17008","DOI":"10.1200\/jco.2019.37.15_suppl.e17008","article-title":"Survival of patients with cervical cancer and diabetes: An exploratory study","volume":"37","author":"Romero","year":"2019","journal-title":"JCO."},{"key":"10.25259\/IJMR_1911_2025\/ref-33","doi-asserted-by":"publisher","first-page":"e28","DOI":"10.3802\/jgo.2016.27.e28","article-title":"Impact of diabetes mellitus on oncological outcomes after radical hysterectomy for early stage cervical cancer","volume":"27","author":"Jiamset","year":"2016","journal-title":"J Gynecol Oncol."},{"key":"10.25259\/IJMR_1911_2025\/ref-34","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1186\/s12885-022-09510-7","article-title":"Survival outcomes in endometrial cancer patients according to diabetes: A systematic review and meta\u2013analysis","volume":"22","author":"McVicker","year":"2022","journal-title":"BMC Cancer."},{"key":"10.25259\/IJMR_1911_2025\/ref-35","doi-asserted-by":"publisher","first-page":"e0176068","DOI":"10.1371\/journal.pone.0176068","article-title":"The relationship between diabetes and colorectal cancer prognosis: A meta\u2013analysis based on the cohort studies","volume":"12","author":"Zhu","year":"2017","journal-title":"PLoS One."},{"key":"10.25259\/IJMR_1911_2025\/ref-36","first-page":"9509","article-title":"Impact of diabetes and metformin use on prostate cancer outcome of patients treated with radiation therapy: Results from a large institutional database","volume":"25","author":"Taussky","year":"2018","journal-title":"Can J Urol."},{"key":"10.25259\/IJMR_1911_2025\/ref-37","doi-asserted-by":"publisher","first-page":"FSO683","DOI":"10.2144\/fsoa-2020-0150","article-title":"Survival and glycemic control in patients with co\u2013existing squamous cell carcinoma and diabetes mellitus","volume":"7","author":"Ederaine","year":"2021","journal-title":"Future Sci OA."},{"key":"10.25259\/IJMR_1911_2025\/ref-38","doi-asserted-by":"publisher","first-page":"e17040","DOI":"10.1200\/jco.2014.32.15_suppl.e17040","article-title":"Head and neck squamous cell carcinoma (HNSCC), diabetes mellitus (DM), and metformin","volume":"32","author":"Alshehri","year":"2014","journal-title":"JCO."},{"key":"10.25259\/IJMR_1911_2025\/ref-39","doi-asserted-by":"publisher","first-page":"1140","DOI":"10.1111\/jdi.14223","article-title":"Impact of diabetes on the prognosis of patients with oral and oropharyngeal cancer: A meta\u2010analysis","volume":"15","author":"Xu","year":"2024","journal-title":"J Diabetes Investig."},{"key":"10.25259\/IJMR_1911_2025\/ref-40","doi-asserted-by":"publisher","first-page":"2175","DOI":"10.1245\/s10434-010-0996-1","article-title":"Impact of diabetes mellitus on the prognosis of patients with oral squamous cell carcinoma: A retrospective cohort study","volume":"17","author":"Wu","year":"2010","journal-title":"Ann Surg Oncol."},{"key":"10.25259\/IJMR_1911_2025\/ref-41","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1038\/bjc.2016.141","article-title":"Pre\u2013existing diabetes and lung cancer prognosis","volume":"115","author":"Luo","year":"2016","journal-title":"Br J Cancer."},{"key":"10.25259\/IJMR_1911_2025\/ref-42","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1016\/j.athoracsur.2022.07.046","article-title":"Impact of diabetes on pathologic response to multimodality therapy for esophageal cancer","volume":"117","author":"Worrell","year":"2024","journal-title":"Ann Thorac Surg."},{"key":"10.25259\/IJMR_1911_2025\/ref-43","doi-asserted-by":"publisher","first-page":"FSO397","DOI":"10.2144\/fsoa-2019-0038","article-title":"Glycemic control and survival of patients with coexisting diabetes mellitus and gastric or esophageal cancer","volume":"5","author":"Karlin","year":"2019","journal-title":"Future Sci OA."},{"key":"10.25259\/IJMR_1911_2025\/ref-44","doi-asserted-by":"publisher","first-page":"885","DOI":"10.1001\/jama.285.7.885","article-title":"Effect of age and comorbidity in postmenopausal breast cancer patients aged 55 years and older","volume":"285","author":"Yancik","year":"2001","journal-title":"JAMA."},{"key":"10.25259\/IJMR_1911_2025\/ref-45","doi-asserted-by":"publisher","first-page":"1835","DOI":"10.2337\/dc12-0002","article-title":"Diabetes and cause\u2013specific mortality in a prospective cohort of one million U.S. adults","volume":"35","author":"Campbell","year":"2012","journal-title":"Diabetes Care."},{"key":"10.25259\/IJMR_1911_2025\/ref-46","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1016\/j.pan.2019.10.007","article-title":"Diabetes mellitus is associated with unfavorable pathologic features, increased postoperative mortality, and worse long\u2013term survival in resected pancreatic cancer","volume":"20","author":"Hank","year":"2020","journal-title":"Pancreatology."},{"key":"10.25259\/IJMR_1911_2025\/ref-47","doi-asserted-by":"publisher","first-page":"17102","DOI":"10.1038\/srep17102","article-title":"Effect of diabetes mellitus on survival in patients with pancreatic cancer: A systematic review and meta\u2013analysis","volume":"5","author":"Mao","year":"2015","journal-title":"Sci Rep."},{"key":"10.25259\/IJMR_1911_2025\/ref-48","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1200\/JGO.19.00061","article-title":"Influence of preexisting diabetes on survival after a breast cancer diagnosis in first nations women in Ontario, Canada","volume":"6","author":"Sheppard","year":"2020","journal-title":"JCO Glob Oncol."},{"key":"10.25259\/IJMR_1911_2025\/ref-49","doi-asserted-by":"publisher","first-page":"1196","DOI":"10.1016\/j.urology.2013.01.047","article-title":"Toxicity after external beam radiotherapy for prostate cancer: An analysis of late morbidity in men with diabetes mellitus","volume":"81","author":"Kalakota","year":"2013","journal-title":"Urology."},{"key":"10.25259\/IJMR_1911_2025\/ref-50","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/j.ctro.2017.02.003","article-title":"What is the impact of diabetes mellitus on radiation induced acute proctitis after radical radiotherapy for adenocarcinoma prostate? A prospective longitudinal study","volume":"14","author":"Alashkham","year":"2017","journal-title":"Clin Transl Radiat Oncol."},{"key":"10.25259\/IJMR_1911_2025\/ref-51","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1016\/s0360-3016(98)00460-x","article-title":"Diabetes mellitus: A predictor for late radiation morbidity","volume":"43","author":"Herold","year":"1999","journal-title":"Int J Radiat Oncol Biol Phys."},{"key":"10.25259\/IJMR_1911_2025\/ref-52","doi-asserted-by":"publisher","first-page":"7103","DOI":"10.2147\/CMAR.S210095","article-title":"Diabetes mellitus is a predictive factor for radiation pneumonitis after thoracic radiotherapy in patients with lung cancer","volume":"11","author":"Kong","year":"2019","journal-title":"Cancer Manag Res."},{"key":"10.25259\/IJMR_1911_2025\/ref-53","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1188\/12.ONF.449-457","article-title":"Diabetes and cancer: Impact on health\u2013related quality of life","volume":"39","author":"Hershey","year":"2012","journal-title":"Oncol Nurs Forum."},{"key":"10.25259\/IJMR_1911_2025\/ref-54","doi-asserted-by":"publisher","first-page":"779","DOI":"10.1177\/0145721712458835","article-title":"Perceived impact of cancer treatment on diabetes self\u2013management","volume":"38","author":"Hershey","year":"2012","journal-title":"Diabetes Educ."},{"key":"10.25259\/IJMR_1911_2025\/ref-55","doi-asserted-by":"publisher","first-page":"e0176941","DOI":"10.1371\/journal.pone.0176941","article-title":"Glycaemic control in people with type 2 diabetes mellitus during and after cancer treatment: A systematic review and meta\u2013analysis","volume":"12","author":"Pettit","year":"2017","journal-title":"PLoS One."},{"key":"10.25259\/IJMR_1911_2025\/ref-56","doi-asserted-by":"publisher","first-page":"417","DOI":"10.6004\/jnccn.2015.0057","article-title":"Delayed recovery and increased severity of Paclitaxel\u2013induced peripheral neuropathy in patients with diabetes","volume":"13","author":"de la Morena Barrio","year":"2015","journal-title":"J Natl Compr Canc Netw."},{"key":"10.25259\/IJMR_1911_2025\/ref-57","doi-asserted-by":"publisher","first-page":"5735","DOI":"10.3390\/cancers13225735","article-title":"Diabetes and cancer: Risk, challenges, management and outcomes","volume":"13","author":"Shahid","year":"2021","journal-title":"Cancers (Basel)."},{"key":"10.25259\/IJMR_1911_2025\/ref-58","doi-asserted-by":"publisher","first-page":"110414","DOI":"10.1016\/j.intimp.2023.110414","article-title":"Recent advances in immune checkpoint inhibitor\u2013induced type 1 diabetes mellitus","volume":"122","author":"Liao","year":"2023","journal-title":"Int Immunopharmacol."},{"key":"10.25259\/IJMR_1911_2025\/ref-59","doi-asserted-by":"publisher","first-page":"469","DOI":"10.4158\/EP08331.RAR","article-title":"Glucocorticoid\u2013induced hyperglycemia","volume":"15","author":"Clore","year":"2009","journal-title":"Endocr Pract."},{"key":"10.25259\/IJMR_1911_2025\/ref-60","doi-asserted-by":"publisher","first-page":"e18232","DOI":"10.1200\/jco.2017.35.15_suppl.e18232","article-title":"Cancer patients with undiagnosed and poorly managed diabetes mellitus","volume":"35","author":"Kim","year":"2017","journal-title":"JCO."},{"key":"10.25259\/IJMR_1911_2025\/ref-61","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1186\/s12931-021-01754-4","article-title":"Effects of diabetes on the development of radiation pneumonitis","volume":"22","author":"Dong","year":"2021","journal-title":"Respir Res."},{"key":"10.25259\/IJMR_1911_2025\/ref-62","doi-asserted-by":"publisher","first-page":"1011","DOI":"10.1111\/dme.13675","article-title":"The Joint British diabetes societies (JBDS) for inpatient care. Management of hyperglycaemia and steroid (glucocorticoid) therapy: A guideline from the Joint British diabetes societies (JBDS) for inpatient care group","volume":"35","author":"Roberts","year":"2018","journal-title":"Diabet Med."},{"key":"10.25259\/IJMR_1911_2025\/ref-63","doi-asserted-by":"publisher","first-page":"102062","DOI":"10.1016\/j.esmoop.2023.102062","article-title":"Diabetes management in cancer patients an Italian association of medical oncology, Italian association of medical diabetologists, Italian society of diabetology, Italian society of endocrinology and Italian society of pharmacology multidisciplinary consensus position paper","volume":"8","author":"Silvestris","year":"2023","journal-title":"ESMO Open."},{"key":"10.25259\/IJMR_1911_2025\/ref-64","doi-asserted-by":"publisher","first-page":"R207","DOI":"10.1530\/EC-20-0342","article-title":"Management of endocrine immune\u2013related adverse events of immune checkpoint inhibitors: An updated review","volume":"9","author":"Stelmachowska\u2013Bana\u015b","year":"2020","journal-title":"Endocr Connect."},{"key":"10.25259\/IJMR_1911_2025\/ref-65","doi-asserted-by":"publisher","first-page":"534","DOI":"10.31128\/AJGP-01-25-7522","article-title":"Palliative management of type 2 diabetes mellitus in patients with advanced cancer","volume":"54","author":"Weerasinghe","year":"2025","journal-title":"Aust J Gen Pract."},{"key":"10.25259\/IJMR_1911_2025\/ref-66","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1111\/joim.12330","article-title":"Stratified medicine for the use of antidiabetic medication in treatment of type II diabetes and cancer: Where do we go from here?","volume":"277","author":"Emami\u2013Riedmaier","year":"2015","journal-title":"J Intern Med"},{"key":"10.25259\/IJMR_1911_2025\/ref-67","doi-asserted-by":"publisher","first-page":"487","DOI":"10.2337\/dci19-0066","article-title":"2019 Update to: management of hyperglycemia in type 2 diabetes, 2018 a consensus report by the American diabetes association (ADA) and the European association for the study of diabetes (EASD)","volume":"43","author":"Buse","year":"2020","journal-title":"Diabetes Care."},{"key":"10.25259\/IJMR_1911_2025\/ref-68","doi-asserted-by":"publisher","first-page":"1680","DOI":"10.3390\/ijms22041680","article-title":"Diabetes, Antidiabetic medications and cancer risk in type 2 diabetes: Focus on SGLT\u20132 inhibitors","volume":"22","author":"D\u0105browski","year":"2021","journal-title":"Int J Mol Sci."},{"key":"10.25259\/IJMR_1911_2025\/ref-69","doi-asserted-by":"publisher","first-page":"1766","DOI":"10.1007\/s00125-009-1440-6","article-title":"The influence of glucose\u2013lowering therapies on cancer risk in type 2 diabetes","volume":"52","author":"Currie","year":"2009","journal-title":"Diabetologia."},{"key":"10.25259\/IJMR_1911_2025\/ref-70","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1038\/ajg.2011.483","article-title":"Use of antidiabetic agents and the risk of pancreatic cancer: A case\u2013control analysis","volume":"107","author":"Bodmer","year":"2012","journal-title":"Am J Gastroenterol."},{"key":"10.25259\/IJMR_1911_2025\/ref-71","doi-asserted-by":"publisher","first-page":"482","DOI":"10.1111\/1753-0407.12435","article-title":"Cancer risk of sulfonylureas in patients with type 2 diabetes mellitus: A systematic review","volume":"9","author":"Chen","year":"2017","journal-title":"J Diabetes."},{"key":"10.25259\/IJMR_1911_2025\/ref-72","doi-asserted-by":"crossref","first-page":"333","DOI":"10.2174\/15680266113136660067","article-title":"Use of insulin and insulin analogs and risk of cancer \u2014 Systematic review and meta\u2013analysis of observational studies","volume":"8","author":"Karlstad","year":"2013","journal-title":"CDS."},{"key":"10.25259\/IJMR_1911_2025\/ref-73","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1111\/dom.12412","article-title":"Glucose\u2010lowering with exogenous insulin monotherapy in type 2 diabetes: Dose association with all\u2010cause mortality, cardiovascular events and cancer","volume":"17","author":"Holden","year":"2015","journal-title":"Diabetes Obesity Metabolism."}],"container-title":["The Indian Journal of Medical Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/ijmr.org.in\/impact-of-diabetes-mellitus-in-cancer\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/ijmr.org.in\/impact-of-diabetes-mellitus-in-cancer\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T11:20:09Z","timestamp":1774351209000},"score":1,"resource":{"primary":{"URL":"http:\/\/ijmr.org.in\/impact-of-diabetes-mellitus-in-cancer\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,19]]},"references-count":73,"alternative-id":["10.25259\/IJMR_1911_2025"],"URL":"https:\/\/doi.org\/10.25259\/ijmr_1911_2025","relation":{},"ISSN":["0971-5916"],"issn-type":[{"value":"0971-5916","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3,19]]},"article-number":"221"}}