{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,12,20]],"date-time":"2024-12-20T05:38:34Z","timestamp":1734673114674,"version":"3.32.0"},"reference-count":13,"publisher":"Scientific Scholar","content-domain":{"domain":["ijmr.org.in"],"crossmark-restriction":true},"short-container-title":["IJMR"],"abstract":"<jats:sec>\n<jats:title>Background &amp; objectives<\/jats:title>\n<jats:p>Tuberculosis (TB) control programmes routinely use indicators like incidence and mortality. A single indicator, like disability-adjusted life years (DALYs) may yield a more comprehensive burden estimate. This study attempted to estimate the state and district-specific TB burden in Kerala.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>The sole data source for these computations was the <jats:italic>Ni-kshay<\/jats:italic>, notification register for 2017 to 2020, Kerala. Age of the patient and outcome are available in the register. Notified incident TB\/1000, the median age of onset of TB, case fatality due to TB, and the median age of mortality were computed using SPSS software. DALYs was calculated using the DALYs package of the R program, using these input parameters. Disability weight was taken as 0.333. The absolute and relative DALY\/100,000 population was estimated along with the 95% confidence interval (CI).<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>Relative DALYs was highest in 2019 at 1482\/100,000 and lowest at 1124\/100,000 in the year 2020 during the period 2017 to 2020. The districts, which had the highest incidence were not the same as those with the highest DALYs. Ernakulam and Thrissur districts had the highest burden and Idukki had the least burden.<\/jats:p>\n<\/jats:sec>\n<jats:sec>\n<jats:title>Interpretation &amp; conclusions<\/jats:title>\n<jats:p>DALYs estimates for Kerala showed an increasing trend before 2020, which could be due to the increased efforts to detect TB as part of the elimination drive. The study points towards the need for using DALYs as a measure for prioritizing districts for resource allocation.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/ijmr_368_23","type":"journal-article","created":{"date-parts":[[2024,9,9]],"date-time":"2024-09-09T16:28:32Z","timestamp":1725899312000},"page":"539-546","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Estimation of State and district-specific disability adjusted life years (DALYs) due to tuberculosis for Kerala, India, 2017-2020"],"prefix":"10.25259","volume":"159","author":[{"given":"Zinia T.","family":"Nujum","sequence":"first","affiliation":[{"name":"Department of Community Medicine, Government Medical College, Kollam, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rakesh P.","family":"Suseela","sequence":"additional","affiliation":[{"name":"The Union, South East Asia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.G.","family":"Lakshmi","sequence":"additional","affiliation":[{"name":"National Health Mission, Kerala, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2024,9,7]]},"reference":[{"journal-title":"Global Tuberculosis report 2023","year":"2023","author":"World Health Organization","key":"10.25259\/IJMR_368_23\/ref-1"},{"key":"10.25259\/IJMR_368_23\/ref-3","doi-asserted-by":"crossref","first-page":"S7","DOI":"10.1016\/j.ijid.2021.02.107","article-title":"Global tuberculosis report 2020 - reflections on the global TB burden, treatment and prevention efforts","volume":"113","author":"Chakaya","year":"2021","journal-title":"Int J Infect Dis"},{"key":"10.25259\/IJMR_368_23\/ref-4","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1186\/s12890-021-01740-y","article-title":"Trends in incidence and mortality of tuberculosis in India over past three decades: a joinpoint and age\u2013period\u2013cohort analysis","volume":"21","author":"Dhamnetiya","year":"2021","journal-title":"BMC Pulm Med"},{"key":"10.25259\/IJMR_368_23\/ref-6","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1186\/s12916-021-02063-9","article-title":"Tuberculosis related disability: A systematic review and meta-analysis","volume":"19","author":"Alene","year":"2021","journal-title":"BMC Med"},{"volume-title":"India: Health of the Nation\u2019s States-The India State-Level Disease Burden Initiative","year":"2017","author":"Indian Council of Medical Research, Public Health Foundation of India and Institute for Health Metrics and Evaluation","key":"10.25259\/IJMR_368_23\/ref-8"},{"key":"10.25259\/IJMR_368_23\/ref-9","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.ijtb.2021.04.005","article-title":"Trends and sub-national disparities in TB notifications in India: Insights from HMIS data","volume":"69","author":"Golandaj","year":"2022","journal-title":"Indian J Tuberc"},{"key":"10.25259\/IJMR_368_23\/ref-14","doi-asserted-by":"crossref","first-page":"e1679","DOI":"10.1016\/S2214-109X(21)00367-3","article-title":"Lifetime burden of disease due to incident tuberculosis: A global reappraisal including post-tuberculosis sequelae","volume":"9","author":"Menzies","year":"2021","journal-title":"Lancet Glob Health"},{"key":"10.25259\/IJMR_368_23\/ref-16","doi-asserted-by":"crossref","first-page":"1859","DOI":"10.1016\/S0140-6736(18)32335-3","article-title":"Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990\u20132017: A systematic analysis for the Global Burden of Disease Study 2017","volume":"392","year":"2018","journal-title":"Lancet"},{"key":"10.25259\/IJMR_368_23\/ref-17","doi-asserted-by":"crossref","first-page":"5960","DOI":"10.3390\/ijerph17165960","article-title":"Estimating Disability-Adjusted Life Years due to Tuberculosis in Korea through to the Year 2040","volume":"17","author":"Jang","year":"2020","journal-title":"Int J Environ Res Public Health"},{"key":"10.25259\/IJMR_368_23\/ref-19","doi-asserted-by":"crossref","first-page":"e060197","DOI":"10.1136\/bmjopen-2021-060197","article-title":"Subnational TB claims verification group. Estimation of tuberculosis incidence at the subnational level using three methods to monitor progress towards ending TB in India, 2015-2020","volume":"12","author":"Jeyashree","year":"2022","journal-title":"BMJ Open"},{"key":"10.25259\/IJMR_368_23\/ref-20","doi-asserted-by":"crossref","first-page":"848370","DOI":"10.3389\/fpubh.2022.848370","article-title":"Comparison of disability-adjusted life years (DALYs) and economic burden on people with drug-susceptible tuberculosis and multidrug-resistant tuberculosis in Korea","volume":"10","author":"Lee","year":"2022","journal-title":"Front Public Health"},{"key":"10.25259\/IJMR_368_23\/ref-21","doi-asserted-by":"crossref","first-page":"e007643","DOI":"10.1136\/bmjgh-2021-007643","article-title":"TB morbidity estimates overlook the contribution of post-TB disability: Evidence from urban Malawi","volume":"7","author":"Tomeny","year":"2022","journal-title":"BMJ Glob Health"},{"key":"10.25259\/IJMR_368_23\/ref-23","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1016\/S0140-6736(12)61680-8","article-title":"Common values in assessing health outcomes from disease and injury: Disability weights measurement study for the global burden of disease study 2010","volume":"380","author":"Salomon","year":"2012","journal-title":"Lancet"}],"container-title":["Indian Journal of Medical Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/ijmr.org.in\/estimation-of-state-and-district-specific-disability-adjusted-life-years-dalys-due-to-tuberculosis-for-kerala-india-2017-2020\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/ijmr.org.in\/estimation-of-state-and-district-specific-disability-adjusted-life-years-dalys-due-to-tuberculosis-for-kerala-india-2017-2020\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,20]],"date-time":"2024-12-20T03:30:10Z","timestamp":1734665410000},"score":1,"resource":{"primary":{"URL":"http:\/\/ijmr.org.in\/estimation-of-state-and-district-specific-disability-adjusted-life-years-dalys-due-to-tuberculosis-for-kerala-india-2017-2020\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,7]]},"references-count":13,"alternative-id":["10.25259\/IJMR_368_23"],"URL":"https:\/\/doi.org\/10.25259\/ijmr_368_23","relation":{},"ISSN":["0971-5916"],"issn-type":[{"type":"print","value":"0971-5916"}],"subject":[],"published":{"date-parts":[[2024,9,7]]},"article-number":"539"}}