{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T17:00:07Z","timestamp":1783443607616,"version":"3.54.6"},"reference-count":4,"publisher":"Scientific Scholar","content-domain":{"domain":["indianjnephrol.org"],"crossmark-restriction":true},"short-container-title":["IJN"],"abstract":"<jats:p>Leprosy, an infectious disease known for its debilitating effects on the skin and nerves, can trigger immunologic reactions affecting multiple organs. We present the case of a 57-year-old male who developed acute glomerulonephritis following leprosy treatment. Clinical examination revealed newly developed pitting edema in the legs, along with residual nerve thickening and skin changes. Laboratory findings showed elevated serum creatinine (3.2mg\/dl) accompanied by low C3 and C4 levels. Urinalysis supported the diagnosis of glomerulonephritis. Renal biopsy demonstrated immune complex deposition on immunofluorescence, suggesting a diagnosis of leprosy-related post-treatment immune-mediated glomerulonephritis. Treatment with oral steroids led to complete resolution of the condition.<\/jats:p>","DOI":"10.25259\/ijn_536_23","type":"journal-article","created":{"date-parts":[[2024,6,29]],"date-time":"2024-06-29T10:58:19Z","timestamp":1719658699000},"page":"520-521","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Immune-Mediated Glomerulonephritis as Type 2 Lepra Reaction Posttreatment of Lepromatous Leprosy: A Case Report"],"prefix":"10.25259","volume":"34","author":[{"given":"Divya","family":"Kantak","sequence":"first","affiliation":[{"name":"Department of Medicine, The Grant Government Medical College and Sir J.J. Group of Hospitals, JJ Marg, Nagpada-Mumbai Central, Near Sandhurst Road and J J Police Station, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marius","family":"Dsouza","sequence":"additional","affiliation":[{"name":"Department of Medicine, The Grant Government Medical College and Sir J.J. Group of Hospitals, JJ Marg, Nagpada-Mumbai Central, Near Sandhurst Road and J J Police Station, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2024,6,29]]},"reference":[{"key":"10.25259\/ijn_536_23\/ref-1","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1590\/S0036-46652015000100002","article-title":"Leprosy nephropathy: A review of clinical and histopathological features","volume":"57","author":"Silva Junior","year":"2015","journal-title":"Rev Inst Med Trop Sao Paulo"},{"key":"10.25259\/ijn_536_23\/ref-2","doi-asserted-by":"publisher","first-page":"289","DOI":"10.4103\/IJPM.IJPM_654_17","article-title":"Hansen\u2019s disease with lepra reaction presenting with IgA dominant infection related glomerulonephritis","volume":"63","author":"Indhumathi","year":"2020","journal-title":"Indian J Pathol Microbiol"},{"key":"10.25259\/ijn_536_23\/ref-3","doi-asserted-by":"publisher","first-page":"619","DOI":"10.1136\/bmj.3.5984.619","article-title":"Lepromatous leprosy presenting with polyarthritis, myositis, and immune-complex glomerulonephritis","volume":"3","author":"Iveson","year":"1975","journal-title":"Br Med J"},{"key":"10.25259\/ijn_536_23\/ref-4","doi-asserted-by":"publisher","first-page":"1171","DOI":"10.3109\/0886022X.2015.1057470","article-title":"It is time to review concepts on renal involvement in leprosy: Pre- and post-treatment evaluation of 189 patients","volume":"37","author":"Polito","year":"2015","journal-title":"Ren Fail"}],"container-title":["Indian Journal of Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/indianjnephrol.org\/immune-mediated-glomerulonephritis-as-type-2-lepra-reaction-posttreatment-of-lepromatous-leprosy-a-case-report\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/indianjnephrol.org\/immune-mediated-glomerulonephritis-as-type-2-lepra-reaction-posttreatment-of-lepromatous-leprosy-a-case-report\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,30]],"date-time":"2024-08-30T12:11:46Z","timestamp":1725019906000},"score":1,"resource":{"primary":{"URL":"https:\/\/indianjnephrol.org\/immune-mediated-glomerulonephritis-as-type-2-lepra-reaction-posttreatment-of-lepromatous-leprosy-a-case-report\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,29]]},"references-count":4,"alternative-id":["10.25259\/ijn_536_23"],"URL":"https:\/\/doi.org\/10.25259\/ijn_536_23","relation":{},"ISSN":["1998-3662","0971-4065"],"issn-type":[{"value":"1998-3662","type":"electronic"},{"value":"0971-4065","type":"print"}],"subject":[],"published":{"date-parts":[[2024,6,29]]},"article-number":"520"}}