{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T06:32:40Z","timestamp":1784529160702,"version":"3.55.0"},"reference-count":24,"publisher":"Scientific Scholar","content-domain":{"domain":["jpalliativecare.com"],"crossmark-restriction":true},"short-container-title":["IJPC"],"abstract":"<jats:sec id=\"st1\">\n<jats:title>Objectives:<\/jats:title>\n<jats:p>The assessment of prevalence of delirium in advanced cancer patients admitted in hospice centre and outcome after palliative intervention. The possible related risk factors for development of delirium.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st2\">\n<jats:title>Material and Methods:<\/jats:title>\n<jats:p>This was prospective analytic study done at hospice centre attached with tertiary cancer hospital in Ahmedabad during August 2019 \u2013 July 2021. This study was approved by the Institutional Review Committee. We selected patients according to following inclusion criteria (all patient admitted to hospice centre above 18 years, with advance cancer disease and on best supportive care) and exclusion criteria (Lack of informed consent, Inability to participate in study due to mentally retard or coma). The following information were collected: age, gender, address, type of cancer, comorbidities, history of substance abuse, history of (h\/o) palliative chemotherapy or radiotherapy within last 3month, general condition, ESAS (Edmonton symptom assessment scale), ECOG (Eastern cooperative oncology group), PaP score (palliative prognostic score), medication including opioids, NSAIDs (Non-steroidal anti-inflammatory drugs), steroids, antibiotic, adjuvant analgesic, PPI (Proton pump inhibitor), anti-emetic etc. Delirium diagnosis was based on diagnostic criterion of DSM-IV text revised and MDAS.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st3\">\n<jats:title>Results:<\/jats:title>\n<jats:p>In our study we found prevalence of delirium was 31.29% in advanced cancer patients admitted to hospice centre. We found most common type of delirium is hypoactive (34.7%) and mixed subtype (34.7%) followed by hyperactive (30.4%) delirium. Resolution of delirium was higher among hyperactive delirium (78.57%) followed by mixed subtype (50%) and hypoactive (12.5%). Mortality was higher among patient with hypoactive subtype (81.25%) followed by mixed (43.75%) and hyperactive delirium (14.28%).<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st4\">\n<jats:title>Conclusion:<\/jats:title>\n<jats:p>An identification and assessment of delirium is vital for acceptable end of life care within the palliative care in light of the fact that the presence of delirium is related with morbidity, mortality, prolonged ICU hospitalization, expanded time on a ventilator, and by and large more prominent medical services costs. Clinicians should utilize one of a few approved delirium assessment tools to help evaluate and archive cognitive function. Prevention and recognizing the clinical reason for delirium are generally the best method for diminishing the morbidity from delirium. The study results demonstrate that multi component delirium management or projects are generally proficient to lessen the prevalence and negative outcomes of delirium. It was found that palliative care intervention has quite a positive outcome as it not only focus on the mental health of the patients but also of family members who go through the same amount of distress and also help them to communicate properly and manage to settle the mental state and end the life without pain and distress.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/ijpc_114_2022","type":"journal-article","created":{"date-parts":[[2022,9,7]],"date-time":"2022-09-07T09:57:25Z","timestamp":1662544645000},"page":"82-88","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Prevalence of Delirium in Advance Cancer Patients Admitted in Hospice Centre and Outcome after Palliative Intervention"],"prefix":"10.25259","volume":"29","author":[{"given":"Kikato V.","family":"Chishi","sequence":"first","affiliation":[{"name":"Department of Palliative Medicine, Gujarat Cancer and Research Institute, Ahmedabad, Gujarat, India,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhavna Chirag","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Palliative Medicine, Gujarat Cancer and Research Institute, Ahmedabad, Gujarat, India,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ravi A.","family":"Umrania","sequence":"additional","affiliation":[{"name":"Department of Palliative Medicine, Gujarat Cancer and Research Institute, Ahmedabad, Gujarat, India,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priti Rashmin","family":"Sanghavi","sequence":"additional","affiliation":[{"name":"Department of Palliative Medicine, Gujarat Cancer and Research Institute, Ahmedabad, Gujarat, India,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Varun Shaileshbhai","family":"Yadav","sequence":"additional","affiliation":[{"name":"Department of Palliative Medicine, Gujarat Cancer and Research Institute, Ahmedabad, Gujarat, India,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lekha V.","family":"Raval","sequence":"additional","affiliation":[{"name":"Department of Palliative Medicine, Gujarat Cancer and Research Institute, Ahmedabad, Gujarat, India,"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2022,9,7]]},"reference":[{"key":"10.25259\/IJPC_114_2022\/ref-1","doi-asserted-by":"publisher","first-page":"1048","DOI":"10.1176\/ajp.140.8.1048","article-title":"Delirium in terminally ill cancer patients","volume":"140","author":"Massie","year":"1983","journal-title":"Am J Psychiatry"},{"key":"10.25259\/IJPC_114_2022\/ref-2","doi-asserted-by":"publisher","first-page":"1425","DOI":"10.1634\/theoncologist.2015-0115","article-title":"The frequency, characteristics, and outcomes among cancer patients with delirium admitted to an acute palliative care unit","volume":"20","author":"de la Cruz","year":"2015","journal-title":"Oncologist"},{"key":"10.25259\/IJPC_114_2022\/ref-3","doi-asserted-by":"publisher","first-page":"4193275","DOI":"10.1155\/2018\/4193275","article-title":"Incidence of delirium in critically Ill cancer patients","volume":"2018","author":"S\u00e1nchez-Hurtado","year":"2018","journal-title":"Pain Res Manag"},{"key":"10.25259\/IJPC_114_2022\/ref-4","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1080\/09540260802675460","article-title":"Motor subtypes of delirium: Past, present and future","volume":"21","author":"Meagher","year":"2009","journal-title":"Int Rev Psychiatry"},{"key":"10.25259\/IJPC_114_2022\/ref-5","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1002\/pon.4140","article-title":"The experiences of caregivers of patients with delirium, and their role in its management in palliative care settings: An integrative literature review","volume":"26","author":"Finucane","year":"2017","journal-title":"Psychooncology"},{"key":"10.25259\/IJPC_114_2022\/ref-6","doi-asserted-by":"publisher","first-page":"638","DOI":"10.1089\/jpm.2016.0315","article-title":"Increased symptom expression among patients with delirium admitted to an acute palliative care unit","volume":"20","author":"de la Cruz","year":"2017","journal-title":"J Palliat Med"},{"key":"10.25259\/IJPC_114_2022\/ref-7","doi-asserted-by":"publisher","first-page":"2427","DOI":"10.1007\/s00520-015-2610-3","article-title":"The frequency of missed delirium in patient referred to palliative care in a comprehensive cancer centre","volume":"23","author":"de la Cruz","year":"2015","journal-title":"Supportive Care Cancer"},{"key":"10.25259\/IJPC_114_2022\/ref-8","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1093\/ageing\/afu022","article-title":"Risk factors for incident delirium among older people in acute hospital medical units: A systematic review and meta-analysis","volume":"43","author":"Ahmed","year":"2014","journal-title":"Age Ageing"},{"key":"10.25259\/IJPC_114_2022\/ref-9","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/0165-1781(88)90037-6","article-title":"A symptom rating scale for delirium","volume":"23","author":"Trzepacz","year":"1988","journal-title":"Psychiatry Res"},{"key":"10.25259\/IJPC_114_2022\/ref-10","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1177\/002383099200500103","article-title":"The delirium symptom interview: An interview for the detection of delirium symptoms in hospitalized patients","volume":"5","author":"Albert","year":"1992","journal-title":"J Geriatr Psychiatry Neurol"},{"key":"10.25259\/IJPC_114_2022\/ref-11","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1016\/S0885-3924(96)00316-8","article-title":"The memorial delirium assessment scale","volume":"13","author":"Breitbart","year":"1997","journal-title":"J Pain Symptom Manage"},{"key":"10.25259\/IJPC_114_2022\/ref-12","doi-asserted-by":"publisher","first-page":"1907","DOI":"10.1007\/s00134-008-1177-6","article-title":"Understanding international differences in terminology for delirium and other types of acute brain dysfunction in critically ill patients","volume":"34","author":"Morandi","year":"2008","journal-title":"Intensive Care Med"},{"key":"10.25259\/IJPC_114_2022\/ref-13","doi-asserted-by":"publisher","first-page":"860","DOI":"10.1016\/j.jpainsymman.2013.06.019","article-title":"Palliative sedation in patient with advance cancer followed at home: A prospective study","volume":"47","author":"Mercadante","year":"2014","journal-title":"J Pain Symptom Manag"},{"key":"10.25259\/IJPC_114_2022\/ref-14","doi-asserted-by":"publisher","first-page":"947","DOI":"10.1016\/j.jpainsymman.2013.01.012","article-title":"Validation of edmonton system assessment scale in Korean cancer patient","volume":"46","author":"Kwon","year":"2013","journal-title":"J Pain Symptom Manage"},{"key":"10.25259\/IJPC_114_2022\/ref-15","doi-asserted-by":"publisher","first-page":"728","DOI":"10.1159\/000503095","article-title":"Performance status assessment by using ECOG (Eastern cooperative oncology group) score for cancer patients by oncology healthcare professional","volume":"12","author":"Azam","year":"2019","journal-title":"Cese Rep Oncol"},{"key":"10.25259\/IJPC_114_2022\/ref-16","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1016\/j.jpainsymman.2010.12.013","article-title":"Evaluation of the palliative prognostic score (PaP) and routinely collected clinical data in prognostication of survival for patients referred to a palliative care consultation service in an acute care hospital","volume":"42","author":"Tarumi","year":"2011","journal-title":"J Pain Symptom Manage"},{"key":"10.25259\/IJPC_114_2022\/ref-17","doi-asserted-by":"publisher","first-page":"2898","DOI":"10.1001\/jama.2008.885","article-title":"Agitation and delirium at the end of life: \u201cWe couldn't manage him\u201c","volume":"300","author":"Breitbart","year":"2008","journal-title":"JAMA"},{"key":"10.25259\/IJPC_114_2022\/ref-18","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1159\/000017177","article-title":"Predisposing and precipitating factors for delirium in hospitalized older patients","volume":"10","author":"Inouye","year":"1999","journal-title":"Dement Geriatr Cogn Disord"},{"key":"10.25259\/IJPC_114_2022\/ref-19","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1177\/0269216312457214","article-title":"Delirium prevalence, incidence and implication for screening in specialist palliative care inpatient setting: A systemic review","volume":"27","author":"Hosie","year":"2013","journal-title":"Palliat Med"},{"key":"10.25259\/IJPC_114_2022\/ref-20","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1093\/jjco\/hym155","article-title":"Prevalence, detection and treatment of delirium in terminal cancer inpatients: A prospective survey","volume":"38","author":"Fang","year":"2008","journal-title":"Jpn J Clin Oncol"},{"key":"10.25259\/IJPC_114_2022\/ref-21","first-page":"1","article-title":"Practice guideline for the treatment of patients with delirium. American Psychiatric Association","volume":"156","author":"American Psychiatric Association","year":"1999","journal-title":"Am J Psychiatry"},{"key":"10.25259\/IJPC_114_2022\/ref-22","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1016\/j.ejcsup.2013.07.008","article-title":"Drug-associated delirium in cancer patients","volume":"11","author":"Caraceni","year":"2013","journal-title":"EJC Suppl"},{"key":"10.25259\/IJPC_114_2022\/ref-23","doi-asserted-by":"publisher","first-page":"786","DOI":"10.1001\/archinte.160.6.786","article-title":"Occurrence, causes and outcome of delirium in patients with advance cancer","volume":"160","author":"Lawlor","year":"2000","journal-title":"Arch Itern Med"},{"key":"10.25259\/IJPC_114_2022\/ref-24","doi-asserted-by":"publisher","first-page":"32","DOI":"10.7326\/0003-4819-135-1-200107030-00011","article-title":"Diagnosis and management of delirium near the end of life","volume":"135","author":"Casarett","year":"2001","journal-title":"Ann Intern Med"}],"container-title":["Indian Journal of Palliative Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/jpalliativecare.com\/prevalence-of-delirium-in-advance-cancer-patients-admitted-in-hospice-centre-and-outcome-after-palliative-intervention\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/jpalliativecare.com\/prevalence-of-delirium-in-advance-cancer-patients-admitted-in-hospice-centre-and-outcome-after-palliative-intervention\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,20]],"date-time":"2023-03-20T07:23:11Z","timestamp":1679296991000},"score":1,"resource":{"primary":{"URL":"https:\/\/jpalliativecare.com\/prevalence-of-delirium-in-advance-cancer-patients-admitted-in-hospice-centre-and-outcome-after-palliative-intervention\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,7]]},"references-count":24,"alternative-id":["10.25259\/IJPC_114_2022"],"URL":"https:\/\/doi.org\/10.25259\/ijpc_114_2022","relation":{},"ISSN":["1998-3735","0973-1075"],"issn-type":[{"value":"1998-3735","type":"electronic"},{"value":"0973-1075","type":"print"}],"subject":[],"published":{"date-parts":[[2022,9,7]]},"article-number":"82"}}