{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,16]],"date-time":"2025-02-16T05:02:28Z","timestamp":1739682148626,"version":"3.37.1"},"reference-count":29,"publisher":"Scientific Scholar","content-domain":{"domain":["jpalliativecare.com"],"crossmark-restriction":true},"short-container-title":["IJPC"],"abstract":"<jats:sec id=\"st1\">\n<jats:title>Objectives:<\/jats:title>\n<jats:p>Yoga, renowned for its ability to maintain physical, mental and spiritual well-being, has recently gained prominence as a supportive therapy during conventional breast cancer (BC) treatment. This paradigm shift reflects a growing trend of people embracing yoga to enhance their overall health and aid in managing BC. The objective of this study was to determine the yoga intervention and inflammatory homoeostasis in newly diagnosed BC patients.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st2\">\n<jats:title>Materials and Method:<\/jats:title>\n<jats:p>This study recruited 44 newly diagnosed BC patients at stages II, III and IV (without distant metastasis or other inflammatory diseases), all admitted for neoadjuvant chemotherapy followed by surgery. A prospective non-randomised control design was employed. Baseline assessments were conducted before the first chemotherapy cycle, with follow-ups before the 2<jats:sup>nd<\/jats:sup> and 3<jats:sup>rd<\/jats:sup> chemotherapy cycles, before surgery, and 2 months post-surgery. The outcome was compared with the control group.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st3\">\n<jats:title>Results:<\/jats:title>\n<jats:p>The study showed significant within-subject effects in the yoga intervention group on serum tumour necrosis factor-alpha, interleukin (IL)-1-beta and IL-6 levels, while no significant changes were observed in the control group. Although between groups did not show statistically significant, the mean values indicated a consistent downregulation of proinflammatory markers over time in the yoga group.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st4\">\n<jats:title>Conclusion:<\/jats:title>\n<jats:p>Incorporating yoga as a complementary therapy alongside conventional BC treatment significantly improved the health outcomes of BC patients by modulating proinflammatory markers.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/ijpc_181_2024","type":"journal-article","created":{"date-parts":[[2024,10,7]],"date-time":"2024-10-07T06:24:09Z","timestamp":1728282249000},"page":"1-7","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Yoga Intervention and Inflammatory Homoeostasis in Breast Cancer Patients"],"prefix":"10.25259","volume":"31","author":[{"given":"Kaini Cecilia","family":"Kaje","sequence":"first","affiliation":[{"name":"Department of Medical Surgical Nursing, Nitte Usha Institute of Nursing Sciences, NITTE (Deemed to be University), Mangaluru, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatima","family":"Dsilva","sequence":"additional","affiliation":[{"name":"Department of Medical Surgical Nursing, Nitte Usha Institute of Nursing Sciences, NITTE (Deemed to be University), Mangaluru, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Praveen Kumar","family":"Shetty","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, K.S. Hegde Medical Academy, NITTE (Deemed to be University), Mangaluru, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajashekar","family":"Mohan","sequence":"additional","affiliation":[{"name":"Department of General Surgery, K.S. Hegde Medical Academy, All India Institute of Medical Sciences, Guntur Mangalagiri, Andra Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shishir","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, K.S. Hegde Medical Academy, NITTE (Deemed to be University), Mangaluru, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neevan","family":"Dsouza","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, K.S. 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