{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T14:47:05Z","timestamp":1772462825141,"version":"3.50.1"},"reference-count":18,"publisher":"Scientific Scholar","content-domain":{"domain":["jpalliativecare.com"],"crossmark-restriction":true},"short-container-title":["IJPC"],"abstract":"\nObjectives:<\/jats:title>\nThe corona virus disease-19 (COVID-19) pandemic has affected every domain of human health be it physical or mental. The uncertainty of disease progression in patients with SARS-CoV-2 infection can lead to major psychological and psychiatric concerns that should not be overlooked. The interventions should be directed to the vulnerable population to help them mitigate the stress and anxiety caused by the infection and isolation. We evaluated the effect of meditation and breathing exercises on the well-being of patients with SARS-CoV-2 infection under institutional isolation.<\/jats:p>\n<\/jats:sec>\n\nMaterials and Methods:<\/jats:title>\nWe conducted a randomized control trial on 84 subjects, 18 years and above, asymptomatic, or mildly symptomatic SARS-CoV-2 infected patients under institutional isolation. Subjects were randomly and equally divided into a control group and interventional group. We measured the depression, anxiety, and stress levels as well as quality of sleep in patients after 7 days of meditation and breathing exercises in the intervention group versus standard care in the control group.<\/jats:p>\n<\/jats:sec>\n\nResults:<\/jats:title>\nMeditation and breathing exercises had a statistically significant effect on the depression level (P < 0.001), stress level (P = 0.004), and the quality of sleep [trouble falling asleep (P = 0.007), trouble staying asleep (P = 0.004), and feel tired after waking up in the morning (P = 0.003)]. Further, the positive effect of intervention on the level of anxiety in patients under isolation was also observed; however, the difference was not found to be statistically significant (P = 0.528).<\/jats:p>\n<\/jats:sec>\n\nConclusion:<\/jats:title>\nMeditation and breathing exercises have positive effects on depression, stress levels, and quality of sleep in COVID-19 positive patients under strict institutional isolation.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/ijpc_40_21","type":"journal-article","created":{"date-parts":[[2021,11,26]],"date-time":"2021-11-26T06:51:23Z","timestamp":1637909483000},"page":"490-494","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Effect of Meditation and Breathing Exercises on the Well-being of Patients with SARS-CoV-2 Infection under Institutional Isolation: A Randomized Control Trial"],"prefix":"10.25259","volume":"27","author":[{"given":"Kiran","family":"Mahendru","sequence":"first","affiliation":[{"name":"Department of Onco-Anaesthesia and Palliative Medicine, Dr. B. R. Ambedkar Institute Rotary Cancer Hospital, New Delhi, India,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anuja","family":"Pandit","sequence":"additional","affiliation":[{"name":"Department of Onco-Anaesthesia and Palliative Medicine, National Cancer Institute, New Delhi, India,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vishwajeet","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, All India Institute of Medical Sciences, New Delhi, India,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nandan","family":"Choudhary","sequence":"additional","affiliation":[{"name":"Department of Onco-Anaesthesia and Palliative Medicine, Dr. B. R. Ambedkar Institute Rotary Cancer Hospital, New Delhi, India,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anant","family":"Mohan","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine and Sleep Disorders, All India Institute of Medical Sciences, New Delhi, India,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sushma","family":"Bhatnagar","sequence":"additional","affiliation":[{"name":"Department of Onco-Anaesthesia and Palliative Medicine, Dr. B. R. Ambedkar Institute Rotary Cancer Hospital, New Delhi, India,"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2021,11,26]]},"reference":[{"key":"10.25259\/IJPC_40_21\/ref-1","doi-asserted-by":"publisher","first-page":"1199","DOI":"10.1056\/NEJMoa2001316","article-title":"Early transmission dynamics in Wuhan, China, of novel Coronavirus-infected pneumonia","volume":"382","author":"Li","year":"2020","journal-title":"N Engl J Med"},{"key":"10.25259\/IJPC_40_21\/ref-2","author":"World Health Organization Press Conference","year":"2020","unstructured":"Available from: https:\/\/www.who.int\/emergencies\/diseases\/novel-coronavirus-2019 [Last accessed on 2020 Feb 11]"},{"key":"10.25259\/IJPC_40_21\/ref-3","doi-asserted-by":"publisher","first-page":"112954","DOI":"10.1016\/j.psychres.2020.112954","article-title":"Generalized anxiety disorder, depressive symptoms and sleep quality during COVID-19 outbreak in China: A web-based cross-sectional survey","volume":"288","author":"Huang","year":"2020","journal-title":"Psychiatry Res"},{"key":"10.25259\/IJPC_40_21\/ref-4","doi-asserted-by":"publisher","first-page":"360","DOI":"10.1089\/acm.2020.0129","article-title":"Public health approach of ayurveda and yoga for COVID-19 prophylaxis","volume":"26","author":"Tillu","year":"2020","journal-title":"J Altern Complement Med"},{"key":"10.25259\/IJPC_40_21\/ref-5","doi-asserted-by":"publisher","first-page":"696","DOI":"10.1089\/acm.2017.0102","article-title":"Effect of yoga breathing (Pranayama) on exercise tolerance in patients with chronic obstructive pulmonary disease: A randomized, controlled trial","volume":"23","author":"Kaminsky","year":"2017","journal-title":"J Altern Complement Med"},{"key":"10.25259\/IJPC_40_21\/ref-6","doi-asserted-by":"publisher","first-page":"447","DOI":"10.23736\/S1973-9087.16.04374-4","article-title":"Effects of yogic exercises on functional capacity, lung function and quality of life in participants with obstructive pulmonary disease: A randomized controlled study","volume":"53","author":"Papp","year":"2017","journal-title":"Eur J Phys Rehabil Med"},{"key":"10.25259\/IJPC_40_21\/ref-7","doi-asserted-by":"publisher","first-page":"e100903","DOI":"10.1371\/journal.pone.0100903","article-title":"The effects of mind-body therapies on the immune system: Meta-analysis","volume":"9","author":"Morgan","year":"2014","journal-title":"PLoS One"},{"key":"10.25259\/IJPC_40_21\/ref-8","first-page":"981","article-title":"Exercise, yoga, and meditation for depressive and anxiety disorders","volume":"81","author":"Saeed","year":"2010","journal-title":"Am Fam Physician"},{"key":"10.25259\/IJPC_40_21\/ref-9","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1097\/MCP.0000000000000207","article-title":"The value of mindfulness meditation in the treatment of insomnia","volume":"21","author":"Martires","year":"2015","journal-title":"Curr Opin Pulm Med"},{"key":"10.25259\/IJPC_40_21\/ref-10","doi-asserted-by":"publisher","first-page":"209","DOI":"10.4187\/respcare.02565","article-title":"Effectiveness of controlled breathing techniques on anxiety and depression in hospitalized patients with COPD: A randomized clinical trial","volume":"59","author":"Valenza","year":"2014","journal-title":"Respir Care"},{"key":"10.25259\/IJPC_40_21\/ref-11","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1016\/j.jaim.2017.07.008","article-title":"Effects of yogic breath regulation: A narrative review of scientific evidence","volume":"10","author":"Saoji","year":"2019","journal-title":"J Ayurveda Integr Med"},{"key":"10.25259\/IJPC_40_21\/ref-12","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1037\/1040-3590.10.2.176","article-title":"Psychometric properties of the 42-item and 21-item versions of the depression anxiety stress scales in clinical groups and a community sample","volume":"10","author":"Antony","year":"1998","journal-title":"Psychol Assess"},{"key":"10.25259\/IJPC_40_21\/ref-13","doi-asserted-by":"publisher","DOI":"10.1037\/t01004-000","article-title":"Manual for the Depression Anxiety Stress Scales","author":"Lovibond","year":"1995","edition":"2nd ed"},{"key":"10.25259\/IJPC_40_21\/ref-14","doi-asserted-by":"publisher","first-page":"e00054020","DOI":"10.1590\/0102-311x00054020","article-title":"Stress, anxiety, and depression levels in the initial stage of the COVID-19 outbreak in a population sample in the Northern Spain. 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