{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T10:46:52Z","timestamp":1767869212518,"version":"3.49.0"},"reference-count":26,"publisher":"Scientific Scholar","content-domain":{"domain":["clinicalimagingscience.org"],"crossmark-restriction":true},"short-container-title":["JCIS"],"abstract":"<jats:p>Primary cerebellar angiosarcoma is an exceptionally rare intracranial malignancy, with only 22 cases reported in the literature. We report the case of a 67-year-old male who presented with a severe headache, unsteady gait, and giddiness. Computed tomography of the brain demonstrated a hemorrhagic lesion in the right cerebellar hemisphere with associated vasogenic edema and early hydrocephalus. Magnetic resonance imaging revealed a right cerebellar intra-axial lesion with mixed signal intensities and a characteristic peripheral \u201cbull\u2019s eye\u201d enhancement pattern. Histopathological evaluation showed a vasoformative neoplasm with atypical endothelial cells, high mitotic activity, and immunopositivity for CD31 and erythroblast transformation specific (ETS)-related gene (ERG), consistent with low-grade angiosarcoma. The patient underwent gross total resection and remained recurrence-free 16 months postoperatively. This case underscores the importance of multi-modality imaging in the early recognition of hemorrhagic cerebellar tumors and reinforces the role of radiological-pathological correlation in diagnosis and treatment planning. Given its rarity, diagnosis of cerebellar angiosarcoma requires a high index of suspicion, supported by advanced imaging and immunohistochemical profiling. Multidisciplinary management is essential, and further case documentation is necessary to guide therapeutic strategies and prognostication.<\/jats:p>","DOI":"10.25259\/jcis_214_2025","type":"journal-article","created":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T05:15:22Z","timestamp":1767849322000},"page":"2","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Primary cerebellar angiosarcoma: A rare case of posterior fossa vascular tumor with hemorrhagic presentation and favorable surgical outcome"],"prefix":"10.25259","volume":"16","author":[{"given":"Yi Cong","family":"Chew","sequence":"first","affiliation":[{"name":"Department of Radiology, Sengkang General Hospital, Singapore,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Po Yin","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Anatomical Pathology, Singapore General Hospital, Singapore,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siang Hui","family":"Lai","sequence":"additional","affiliation":[{"name":"Department of Anatomical Pathology, Singapore General Hospital, Singapore,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chi Long","family":"Ho","sequence":"additional","affiliation":[{"name":"Department of Radiology, Sengkang General Hospital, Singapore,"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2026,1,9]]},"reference":[{"key":"10.25259\/JCIS_214_2025\/ref-1","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1111\/neup.12178","article-title":"Primary central nervous system angiosarcoma: A case report and literature review","volume":"35","author":"La Corte","year":"2015","journal-title":"Neuropathology"},{"key":"10.25259\/JCIS_214_2025\/ref-2","doi-asserted-by":"publisher","first-page":"171","DOI":"10.4274\/tnd.10693","article-title":"Central nervous system angiosarcoma: A case report","volume":"24","author":"Sari","year":"2018","journal-title":"T\u00fcrk N\u00f6rol Derg"},{"key":"10.25259\/JCIS_214_2025\/ref-3","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1186\/1752-1947-6-251","article-title":"Primary central nervous system angiosarcoma: Two case reports","volume":"6","author":"Hackney","year":"2012","journal-title":"J Med Case Rep"},{"key":"10.25259\/JCIS_214_2025\/ref-4","doi-asserted-by":"publisher","first-page":"806","DOI":"10.3171\/jns.1988.68.5.0806","article-title":"Primary cerebral angiosarcoma. 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