{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T04:40:14Z","timestamp":1759725614789,"version":"build-2065373602"},"reference-count":19,"publisher":"Scientific Scholar","content-domain":{"domain":["clinicalimagingscience.org"],"crossmark-restriction":true},"short-container-title":["JCIS"],"abstract":"<jats:sec id=\"st1\">\n<jats:title>Objectives:<\/jats:title>\n<jats:p>This study aimed to assess the diagnostic performance of whole-body magnetic resonance imaging (wbMRI) in comparison with gold standard <jats:sup>18<\/jats:sup>F-fluorodeoxyglucose-positron emission tomography\/computed tomography (FDG-PET\/CT) for detecting metastases in patients with gynecological cancer (GCa).<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st2\">\n<jats:title>Material and Methods:<\/jats:title>\n<jats:p>We prospectively enrolled five histologically proven GCa patients who underwent FDG-PET\/CT and were identified with metastatic disease in their lungs. We customized a wbMRI protocol including ultra-short echo time (UTE) MRI sequence with a stack-of-spiral acquisition and imaged the patients on a 3 Tesla MRI scanner. Nuclear medicine physicians and radiologists reviewed the PET\/CT and MRI images respectively and compared the findings for each patient. PET\/CT images were accepted gold standard. We calculated the sensitivities of wbMRI and assessed the differences in diagnostic performance between PET\/CT and wbMRI using McNemar\u2019s test (<jats:italic>P<\/jats:italic> &lt; 0.05).<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st3\">\n<jats:title>Results:<\/jats:title>\n<jats:p>Three patients had cervical cancer while two had ovarian cancer. FDG-PET\/CT detected a total of 44 findings (including nodules, lesions, and lymph nodes) across the five patients. WbMRI showed 39 findings with a sensitivity of 89%. McNemar\u2019s test revealed no statistically significant difference between wbMRI and PET\/CT. The pre-contrast UTE sequence displayed 33 findings (33\/44) and in detecting lung nodules, it displayed an accuracy of 70% (7\/10).<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st4\">\n<jats:title>Conclusion:<\/jats:title>\n<jats:p>This pilot study suggests that wbMRI demonstrates no statistically significant difference compared to <jats:sup>18<\/jats:sup>FDG-PET\/CT for detecting gynecological metastases. Furthermore, the UTE sequence proved valuable as part of the wbMRI protocol for detecting metastases without the need for a contrast agent.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/jcis_59_2025","type":"journal-article","created":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T03:58:27Z","timestamp":1759723107000},"page":"38","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Whole-body magnetic resonance imaging with ultra-short echo time sequence versus fluorodeoxyglucose-positron emission tomography\/computed tomography in detecting gynecologic metastases"],"prefix":"10.25259","volume":"15","author":[{"given":"Kazim Ziya","family":"Gumus","sequence":"first","affiliation":[{"name":"Department of Radiology, University of Florida College of Medicine, Jacksonville, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karina","family":"Hew","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of Florida, Jacksonville, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Savas","family":"Ozdemir","sequence":"additional","affiliation":[{"name":"Department of Radiology, University of Florida College of Medicine, Jacksonville, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjay","family":"Lamsal","sequence":"additional","affiliation":[{"name":"Department of Radiology, University of Florida College of Medicine, Jacksonville, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sindhu","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Radiology, University of Florida College of Medicine, Jacksonville, United 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