{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T00:39:01Z","timestamp":1785458341363,"version":"3.56.0"},"reference-count":14,"publisher":"Scientific Scholar","content-domain":{"domain":["clinicalimagingscience.org"],"crossmark-restriction":true},"short-container-title":["JCIS"],"abstract":"<jats:p>We report a case of a 73-year-old woman presenting with intracranial and extracranial meningioma with perineural spread crossing the foramen rotundum and pterygopalatine fossa, primarily along the maxillary nerve. She visited our hospital with the chief complaint of the left cheek swelling. Subsequent magnetic resonance imaging revealed a well-demarcated mass containing intracranial (cavernous sinus, Meckel\u2019s cave, and middle cranial fossa) and extracranial components (pterygopalatine fossa, orbit, nasal cavity, ethmoid and sphenoid sinuses, infratemporal fossa, and buccal space) through the foramen rotundum. A biopsy specimen was obtained from the cheek mass, and the histopathological diagnosis was meningothelial meningioma.<\/jats:p>","DOI":"10.25259\/jcis_97_2024","type":"journal-article","created":{"date-parts":[[2024,9,23]],"date-time":"2024-09-23T06:18:21Z","timestamp":1727072301000},"page":"36","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Computed tomography and magnetic resonance imaging findings of intracranial and extracranial meningioma with perineural spread through the foramen rotundum: A case report"],"prefix":"10.25259","volume":"14","author":[{"given":"Taketo","family":"Suto","sequence":"first","affiliation":[{"name":"Department of Radiology, Gifu University, Gifu, Japan,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroki","family":"Kato","sequence":"additional","affiliation":[{"name":"Department of Radiology, Gifu University, Gifu, Japan,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takenori","family":"Ogawa","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Gifu University, Gifu, Japan,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masayuki","family":"Matsuo","sequence":"additional","affiliation":[{"name":"Department of Radiology, Gifu University, Gifu, Japan,"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2024,9,23]]},"reference":[{"key":"10.25259\/JCIS_97_2024\/ref-1","doi-asserted-by":"publisher","first-page":"20210099","DOI":"10.1259\/bjr.20210099","article-title":"Mimics of perineural tumor spread in the head and neck","volume":"94","author":"Tanwar","year":"2021","journal-title":"Br J Radiol"},{"key":"10.25259\/JCIS_97_2024\/ref-2","doi-asserted-by":"publisher","first-page":"1109","DOI":"10.1016\/j.ijrobp.2018.12.009","article-title":"Perineural invasion and perineural tumor spread in head and neck cancer","volume":"103","author":"Bakst","year":"2019","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.25259\/JCIS_97_2024\/ref-3","doi-asserted-by":"publisher","first-page":"8948","DOI":"10.3390\/curroncol30100647","article-title":"Unraveling the mysteries of perineural invasion in benign and malignant conditions","volume":"30","author":"Bahmad","year":"2023","journal-title":"Curr Oncol"},{"key":"10.25259\/JCIS_97_2024\/ref-4","first-page":"701","article-title":"Perineural spread of head and neck tumors: How accurate is MR imaging?","volume":"19","author":"Nemzek","year":"1998","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.25259\/JCIS_97_2024\/ref-5","doi-asserted-by":"publisher","first-page":"895","DOI":"10.1007\/s00247-005-1472-0","article-title":"Childhood atypical meningioma with perineural spread: MR findings","volume":"35","author":"Wei","year":"2005","journal-title":"Pediatr Radiol"},{"key":"10.25259\/JCIS_97_2024\/ref-6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3941\/jrcr.v9i12.2648","article-title":"A rare case of atypical skull base meningioma with perineural spread","volume":"9","author":"Walton","year":"2015","journal-title":"J Radiol Case Rep"},{"key":"10.25259\/JCIS_97_2024\/ref-7","doi-asserted-by":"publisher","first-page":"637","DOI":"10.1080\/02688697.2018.1530730","article-title":"An unusual case of a grade I meningioma with perineural spread","volume":"37","author":"Fadelalla","year":"2023","journal-title":"Br J Neurosurg"},{"key":"10.25259\/JCIS_97_2024\/ref-8","doi-asserted-by":"publisher","first-page":"566","DOI":"10.1055\/s-0043-1777743","article-title":"Atypical meningioma with perineural spread along hypoglossal nerve","volume":"34","author":"Rastogi","year":"2024","journal-title":"Indian J Radiol Imaging"},{"key":"10.25259\/JCIS_97_2024\/ref-9","doi-asserted-by":"publisher","first-page":"3379","DOI":"10.1002\/cncr.24396","article-title":"Perineural invasion in cancer: A review of the literature","volume":"115","author":"Liebig","year":"2009","journal-title":"Cancer"},{"key":"10.25259\/JCIS_97_2024\/ref-10","doi-asserted-by":"publisher","first-page":"1925","DOI":"10.1111\/odi.13190","article-title":"Activation of BDNF\/TrkB\/Akt pathway is associated with aggressiveness and unfavorable survival in oral squamous cell carcinoma","volume":"25","author":"Moraes","year":"2019","journal-title":"Oral Dis"},{"key":"10.25259\/JCIS_97_2024\/ref-11","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1186\/s12885-016-2218-0","article-title":"More expression of BDNF associates with lung squamous cell carcinoma and is critical to the proliferation and invasion of lung cancer cells","volume":"16","author":"Zhang","year":"2016","journal-title":"BMC Cancer"},{"key":"10.25259\/JCIS_97_2024\/ref-12","doi-asserted-by":"publisher","first-page":"4221","DOI":"10.3892\/etm.2019.8100","article-title":"Expression of BDNF, TrkB, VEGF and CD105 is associated with pelvic lymph node metastasis and prognosis in IB2-stage squamous cell carcinoma","volume":"18","author":"Qi","year":"2019","journal-title":"Exp Ther Med"},{"key":"10.25259\/JCIS_97_2024\/ref-13","doi-asserted-by":"publisher","first-page":"1373","DOI":"10.3892\/or_00000363","article-title":"Immunohistochemical profile of neurotrophins in human cranial dura mater and meningiomas","volume":"21","author":"Artico","year":"2009","journal-title":"Oncol Rep"},{"key":"10.25259\/JCIS_97_2024\/ref-14","doi-asserted-by":"publisher","first-page":"CNS72","DOI":"10.2217\/cns-2021-0003","article-title":"Meningioma: Not always a benign tumor. A review of advances in the treatment of meningiomas","volume":"10","author":"Maggio","year":"2021","journal-title":"CNS Oncol"}],"container-title":["Journal of Clinical Imaging Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/clinicalimagingscience.org\/computed-tomography-and-magnetic-resonance-imaging-findings-of-intracranial-and-extracranial-meningioma-with-perineural-spread-through-the-foramen-rotundum-a-case-report\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/clinicalimagingscience.org\/computed-tomography-and-magnetic-resonance-imaging-findings-of-intracranial-and-extracranial-meningioma-with-perineural-spread-through-the-foramen-rotundum-a-case-report\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,23]],"date-time":"2024-09-23T06:18:24Z","timestamp":1727072304000},"score":1,"resource":{"primary":{"URL":"https:\/\/clinicalimagingscience.org\/computed-tomography-and-magnetic-resonance-imaging-findings-of-intracranial-and-extracranial-meningioma-with-perineural-spread-through-the-foramen-rotundum-a-case-report\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,23]]},"references-count":14,"alternative-id":["10.25259\/JCIS_97_2024"],"URL":"https:\/\/doi.org\/10.25259\/jcis_97_2024","relation":{},"ISSN":["2156-5597","2156-7514"],"issn-type":[{"value":"2156-5597","type":"electronic"},{"value":"2156-7514","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9,23]]},"article-number":"36"}}