{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T21:57:15Z","timestamp":1780091835804,"version":"3.54.0"},"reference-count":8,"publisher":"Scientific Scholar","content-domain":{"domain":["ruralneuropractice.com"],"crossmark-restriction":true},"short-container-title":["JNRP"],"abstract":"<jats:p>Morvan\u2019s syndrome is a rare anti-contactin-associated protein-like 2 (CASPR2) antibody-mediated autoimmune disorder. The clinical features of this syndrome include muscular twitching, insomnia, dysautonomia, peripheral nerve hyperexcitability, and fluctuating delirium. An underlying tumor is commonly found among Morvan\u2019s syndrome cases, with thymoma being the most frequent association. We describe an unusual case of a 39-year-old female with excruciating bilateral leg pain, insomnia, hyperhidrosis, peripheral nerve hyperexcitability, serum anti-CASPR2 antibody positivity, and a solid pseudopapillary tumor of the pancreas on histopathology. Furthermore, the patient\u2019s symptoms improved after receiving intravenous immunoglobulin (0.4 g\/kg per day for 5 days). To the best of our knowledge, this is the first case of Morvan syndrome associated with a solid pseudopapillary pancreatic tumor to be reported in the literature to date. Our case adds to the spectrum of malignancies that are associated with Morvan\u2019s syndrome. The recognition of this rare syndrome and its various associations are important for the neurologist, as it is a potentially treatable condition.<\/jats:p>","DOI":"10.25259\/jnrp-2022-3-49","type":"journal-article","created":{"date-parts":[[2022,11,18]],"date-time":"2022-11-18T11:33:52Z","timestamp":1668771232000},"page":"768-770","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Morvan\u2019s syndrome: An unusual presentation of a solid pseudopapillary pancreatic tumor"],"prefix":"10.25259","volume":"13","author":[{"given":"Alvee","family":"Saluja","sequence":"first","affiliation":[{"name":"Department of Neurology, Lady Hardinge Medical College, New Delhi, India,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jyoti","family":"Verma","sequence":"additional","affiliation":[{"name":"Department of Neurology, Lady Hardinge Medical College, New Delhi, India,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahbaz","family":"Anees","sequence":"additional","affiliation":[{"name":"Department of Neurology, Lady Hardinge Medical College, New Delhi, India,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anita","family":"Nangia","sequence":"additional","affiliation":[{"name":"Department of Pathology, Lady Hardinge Medical College, New Delhi, India,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajinder K.","family":"Dhamija","sequence":"additional","affiliation":[{"name":"Department of Neurology, Lady Hardinge Medical College, New Delhi, India,"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2022,11,18]]},"reference":[{"key":"10.25259\/JNRP-2022-3-49\/ref-1","doi-asserted-by":"publisher","first-page":"440","DOI":"10.1097\/00004691-200411000-00008","article-title":"Neurophysiologic studies in Morvan syndrome","volume":"21","author":"Josephs","year":"2004","journal-title":"J Clin Neurophysiol"},{"key":"10.25259\/JNRP-2022-3-49\/ref-2","doi-asserted-by":"publisher","first-page":"1367","DOI":"10.1016\/S0140-6736(16)31459-3","article-title":"Morvan syndrome as a paraneoplastic disorder of thymoma with anti-CASPR2 antibodies","volume":"389","author":"Vale","year":"2017","journal-title":"Lancet"},{"key":"10.25259\/JNRP-2022-3-49\/ref-3","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1212\/WNL.0000000000004861","article-title":"Morvan syndrome associated with CASPR2 and LGI1 antibodies in a child","volume":"90","author":"Nikolaus","year":"2018","journal-title":"Neurology"},{"key":"10.25259\/JNRP-2022-3-49\/ref-4","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1002\/ana.24979","article-title":"Expanded phenotypes and outcomes among 256 LGI1\/CASPR2-IgG-positive patients","volume":"82","author":"Gadoth","year":"2017","journal-title":"Ann 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