{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T14:00:25Z","timestamp":1769349625431,"version":"3.49.0"},"reference-count":29,"publisher":"Scientific Scholar","content-domain":{"domain":["ruralneuropractice.com"],"crossmark-restriction":true},"short-container-title":["JNRP"],"abstract":"<jats:sec id=\"st1\">\n<jats:title>Objectives:<\/jats:title>\n<jats:p>Cerebral microbleeds (MBs) are recently described entity on magnetic resonance (MR) neuroimaging and are considered one of the markers of small vessel disease. We aimed to study the clinicoradiological features of cerebral MBs that were diagnosed in MR neuroimaging.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st2\">\n<jats:title>Materials and Methods:<\/jats:title>\n<jats:p>We studied 109 South Indian patients, who presented to a tertiary care institution for MR neuroimaging with cerebral MBs as diagnosed on MR neuroimaging based on either the gradient T2* imaging or susceptibility-weighted imaging. The clinical details and coexisting MR features of infarcts, macrohemorrhages, lacunar infarcts, and white matter leukoaraiosis were evaluated and analyzed.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st3\">\n<jats:title>Results:<\/jats:title>\n<jats:p>Of 109 patients, 79 were males and 30 were females. Associated clinical comorbidities noted include hypertension (62.39%), diabetes (23.85%), and alcoholism (31.19%) apart from the history of anti-platelet\/anti-coagulant usage (15.5%), previous cardiac disease (12.84%), and previous stroke\/transient ischemic attacks (9.17%). Other co-existing neuroimaging abnormalities noted include cortical infarcts (27.52%), old hemorrhages (29.36%), lacunar infarcts (56.88%), and white matter leukaraiosis (67.89%).<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st4\">\n<jats:title>Conclusion:<\/jats:title>\n<jats:p>The clinicoradiological features of cerebral MBs in South Indian patients are similar to other Asian and Western studies with significant coexistence of clinical comorbidities and imaging features of small vessel changes. Further studies with a larger sample are needed to correlate the grade of MBs to the individual risk of these clinicoradiological characteristics.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/jnrp_331_2023","type":"journal-article","created":{"date-parts":[[2024,3,20]],"date-time":"2024-03-20T05:23:15Z","timestamp":1710912195000},"page":"300-306","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Clinicoradiological features of cerebral microbleeds diagnosed on magnetic resonance neuroimaging"],"prefix":"10.25259","volume":"15","author":[{"given":"Jayaram","family":"Bharath","sequence":"first","affiliation":[{"name":"Department of Radio-Diagnosis, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohan","family":"Amuthabharathi","sequence":"additional","affiliation":[{"name":"Department of Radio-Diagnosis, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kulumani M.","family":"Sivasubramaniyan","sequence":"additional","affiliation":[{"name":"Department of Radio-Diagnosis, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Subathra","family":"Adithan","sequence":"additional","affiliation":[{"name":"Department of Radio-Diagnosis, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sunil K.","family":"Narayan","sequence":"additional","affiliation":[{"name":"Department of Neurology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vellathussery C.","family":"Sunitha","sequence":"additional","affiliation":[{"name":"Department of Radio-Diagnosis, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krishnan","family":"Nagarajan","sequence":"additional","affiliation":[{"name":"Department of Radio-Diagnosis, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India,"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2024,3,20]]},"reference":[{"key":"10.25259\/JNRP_331_2023\/ref-1","first-page":"637","article-title":"Histopathologic analysis of foci of signal loss on gradient-echo T2*-weighted MR images in patients with spontaneous intracerebral hemorrhage: Evidence of microangiopathy-related microbleeds","volume":"20","author":"Fazekas","year":"1999","journal-title":"AJNR Am J 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