{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T21:46:27Z","timestamp":1789767987173,"version":"4.0.1"},"reference-count":13,"publisher":"Scientific Scholar","content-domain":{"domain":["ruralneuropractice.com"],"crossmark-restriction":true},"short-container-title":["JNRP"],"abstract":"<jats:p>Optic nerve (ON) sheath meningocele is an enlargement of the ON sheath, consisting in a cerebrospinal fluid collection along the perineural space of the optic nerve. It should be considered primary when it is not associated with orbital-cerebral neoplasm or with cranio-orbital junction malformations. Here, we report a case of bilateral primary idiopathic ON meningocele with gradual vision loss, treated with acetazolamide, which showed a maintained visual recovery and partial improvement during a 6-month follow-up period. The literature review retrieved eight cases of primary idiopathic ON sheath meningocele: ON sheath fenestration is considered in patients with progressive and severe vision loss, otherwise, acetazolamide treatment is indicated with good results on symptoms control, as confirmed in our case report.<\/jats:p>","DOI":"10.25259\/jnrp_5_2022","type":"journal-article","created":{"date-parts":[[2022,11,2]],"date-time":"2022-11-02T06:28:50Z","timestamp":1667370530000},"page":"781-784","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Bilateral idiopathic optic nerve sheath meningocele: A case report and literature review"],"prefix":"10.25259","volume":"13","author":[{"given":"Alberto","family":"Morello","sequence":"first","affiliation":[{"name":"Department of Neuroscience, University of Turin, Turin, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Bianconi","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, University of Turin, Turin, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Cogoni","sequence":"additional","affiliation":[{"name":"Department of Radiology, CTO Hospital, Turin, Italy,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvana","family":"Borgarello","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, CTO Hospital, Turin, Italy,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diego","family":"Garbossa","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, University of Turin, Turin, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara Massa","family":"Micon","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, CTO Hospital, Turin, Italy,"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2022,11,2]]},"reference":[{"key":"10.25259\/JNRP_5_2022\/ref-1","doi-asserted-by":"publisher","first-page":"1519","DOI":"10.1016\/S0161-6420(90)32382-5","article-title":"Optic nerve sheath meningoceles. Clinical and radiographic features in 13 cases with a review of the literature","volume":"97","author":"Garrity","year":"1990","journal-title":"Ophthalmology"},{"key":"10.25259\/JNRP_5_2022\/ref-2","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1007\/BF01105565","article-title":"Surgically verified case of optic sheath nerve meningocele: Case report with review of the literature","volume":"20","author":"Lunardi","year":"1997","journal-title":"Neurosurg Rev"},{"key":"10.25259\/JNRP_5_2022\/ref-3","doi-asserted-by":"publisher","first-page":"661","DOI":"10.2147\/OPTH.S2689","article-title":"Optic nerve sheath meningocele","volume":"2","author":"Mesa-Guti\u00e9rrez","year":"2008","journal-title":"Clin Ophthalmol"},{"key":"10.25259\/JNRP_5_2022\/ref-4","doi-asserted-by":"publisher","first-page":"800","DOI":"10.1038\/sj.eye.6700212","article-title":"Bilateral idopathic optic nerve sheath meningocele associated with unilateral transient cystoid macular oedema","volume":"16","author":"Shanmuganathan","year":"2002","journal-title":"Eye (Lond)"},{"key":"10.25259\/JNRP_5_2022\/ref-5","doi-asserted-by":"publisher","first-page":"213","DOI":"10.2147\/IMCRJ.S166655","article-title":"Optic nerve sheath meningocele","volume":"11","author":"Algarni","year":"2018","journal-title":"Int Med Case Rep J"},{"key":"10.25259\/JNRP_5_2022\/ref-6","doi-asserted-by":"publisher","first-page":"1336","DOI":"10.1016\/S0161-6420(86)33577-2","article-title":"The natural history and CT appearance of acquired hyperopia with choroidal folds","volume":"93","author":"Dailey","year":"1986","journal-title":"Ophthalmology"},{"key":"10.25259\/JNRP_5_2022\/ref-7","doi-asserted-by":"publisher","first-page":"349","DOI":"10.4103\/jnrp.jnrp_232_18","article-title":"Dural ectasia of the optic nerve: A rare presentation in neurofibromatosis Type I","volume":"10","author":"Shaikh","year":"2019","journal-title":"J Neurosci Rural Pract"},{"key":"10.25259\/JNRP_5_2022\/ref-8","doi-asserted-by":"publisher","first-page":"728","DOI":"10.1097\/00004728-199409000-00009","article-title":"Dural ectasia of the optic nerve sheath in neurofibromatosis Type 1: CT and MR features","volume":"18","author":"L\u00f6vblad","year":"1994","journal-title":"J Comput Assist Tomogr"},{"key":"10.25259\/JNRP_5_2022\/ref-9","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1007\/s00234-006-0095-y","article-title":"Idiopathic intracranial hypertension: The validity of cross-sectional neuroimaging signs","volume":"48","author":"Agid","year":"2006","journal-title":"Neuroradiology"},{"key":"10.25259\/JNRP_5_2022\/ref-10","first-page":"1130","article-title":"Dural ectasia of optic nerve-an important clinical finding in marfan's syndrome","volume":"2","author":"Mehta","year":"2016","journal-title":"Open J Clin Med Case Rep"},{"key":"10.25259\/JNRP_5_2022\/ref-11","doi-asserted-by":"publisher","first-page":"78","DOI":"10.3109\/01658107.2013.766219","article-title":"Optic nerve sheath meningocele: A case report","volume":"37","author":"Halimi","year":"2013","journal-title":"Neuroophthalmology"},{"key":"10.25259\/JNRP_5_2022\/ref-12","doi-asserted-by":"publisher","first-page":"e85","DOI":"10.1097\/IOP.0000000000001270","article-title":"Optic nerve sheath meningocele with optic disc pit: A rare finding","volume":"35","author":"Jain","year":"2019","journal-title":"Ophthal Plast Reconstr Surg"},{"key":"10.25259\/JNRP_5_2022\/ref-13","doi-asserted-by":"publisher","first-page":"e160","DOI":"10.1097\/IOP.0000000000000932","article-title":"Stabilization of visual function after optic nerve sheath fenestration for optic nerve meningocele","volume":"33","author":"Mahatma","year":"2017","journal-title":"Ophthalmic Plast Reconstr Surg"}],"container-title":["Journal of Neurosciences in Rural Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/ruralneuropractice.com\/bilateral-idiopathic-optic-nerve-sheath-meningocele-a-case-report-and-literature-review\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/ruralneuropractice.com\/bilateral-idiopathic-optic-nerve-sheath-meningocele-a-case-report-and-literature-review\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,20]],"date-time":"2023-03-20T12:32:11Z","timestamp":1679315531000},"score":1,"resource":{"primary":{"URL":"https:\/\/ruralneuropractice.com\/bilateral-idiopathic-optic-nerve-sheath-meningocele-a-case-report-and-literature-review\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,2]]},"references-count":13,"alternative-id":["10.25259\/JNRP_5_2022"],"URL":"https:\/\/doi.org\/10.25259\/jnrp_5_2022","relation":{},"ISSN":["0976-3155","0976-3147"],"issn-type":[{"value":"0976-3155","type":"electronic"},{"value":"0976-3147","type":"print"}],"subject":[],"published":{"date-parts":[[2022,11,2]]},"article-number":"781"}}