{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T00:36:26Z","timestamp":1760056586606,"version":"build-2065373602"},"reference-count":20,"publisher":"Scientific Scholar","content-domain":{"domain":["nmji.in"],"crossmark-restriction":true},"short-container-title":["NMJI"],"abstract":"<jats:sec id=\"st1\">\n<jats:title>Background<\/jats:title>\n<jats:p>Certain dermatological disorders can result in major morbidity and mortality. There are few studies worldwide regarding mortality in dermatology, with a paucity of data on the epidemiological and aetiological profile of sepsis in dermatology patients, necessitating further research and awareness. We aimed to bridge this gap by studying the mortality associated with dermatological diseases at a tertiary care hospital in southern India.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st2\">\n<jats:title>Methods<\/jats:title>\n<jats:p>Inpatient records of all patients admitted over a period of 5 years (2018\u20132022) with a dermatological disease and systemic complications resulting in mortality were reviewed. Details regarding the nature of the disorder, disease characteristics, investigations, treatment, and course of hospitalization were collected and analyzed.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st3\">\n<jats:title>Results<\/jats:title>\n<jats:p>Thirteen patients with dermatological disease-related mortality were included in the study. Mortality was highest in the 4th\u20136th decade age group. Cutaneous adverse drug reactions accounted for the highest mortality. Septic shock was the most common cause of death in these patients.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st4\">\n<jats:title>Conclusion<\/jats:title>\n<jats:p>Cutaneous adverse drug reactions are a common cause of mortality among dermatology inpatients. Sepsis and multiorgan dysfunction are important complications in these patients, highlighting the role of strict aseptic precautions, barrier nursing and multidisciplinary care in patients with extensive skin involvement.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/nmji_1205_2023","type":"journal-article","created":{"date-parts":[[2025,9,18]],"date-time":"2025-09-18T09:56:49Z","timestamp":1758189409000},"page":"203-206","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Mortality in dermatology: A retrospective study of cause and course"],"prefix":"10.25259","volume":"38","author":[{"given":"CAROL","family":"LOBO","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"AKANKSHA PRASAD","family":"CHERALA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"AISHWARYA","family":"SATYANARAYANA","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"VIJAY","family":"AITHAL","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2025,9,18]]},"reference":[{"key":"10.25259\/NMJI_1205_2023\/ref-1","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1001\/jamadermatol.2016.5538","article-title":"Global skin disease morbidity and mortality: An update from the global burden of disease study 2013","volume":"153","author":"Karimkhani","year":"2017","journal-title":"JAMA Dermatol"},{"key":"10.25259\/NMJI_1205_2023\/ref-2","doi-asserted-by":"publisher","first-page":"943","DOI":"10.21037\/jtd.2017.03.125","article-title":"SIRS, qSOFA and new sepsis definition","volume":"9","author":"Marik","year":"2017","journal-title":"J Thorac Dis"},{"key":"10.25259\/NMJI_1205_2023\/ref-3","doi-asserted-by":"publisher","first-page":"342","DOI":"10.25259\/IJDVL_711_20","article-title":"Profile of dermatology inpatients and admissions over a four year period in a tertiary level government teaching hospital in North India","volume":"88","author":"Gupta","year":"2022","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"10.25259\/NMJI_1205_2023\/ref-4","doi-asserted-by":"publisher","first-page":"105","DOI":"10.4103\/injms.injms_131_21","article-title":"Mortality in dermatology: A closer look","volume":"13","author":"Bhandare","year":"2022","journal-title":"Indian J Med Spec"},{"key":"10.25259\/NMJI_1205_2023\/ref-5","doi-asserted-by":"publisher","first-page":"23","DOI":"10.4103\/0378-6323.13781","article-title":"Astudy of mortality in dermatology","volume":"71","author":"Nair","year":"2005","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"10.25259\/NMJI_1205_2023\/ref-6","doi-asserted-by":"publisher","first-page":"626","DOI":"10.4103\/ijd.IJD_284_17","article-title":"Inpatient mortality resulting from dermatological disorders at a tertiary care center in Eastern India: A record-based observational study","volume":"62","author":"Chowdhury","year":"2017","journal-title":"Indian J Dermatol"},{"key":"10.25259\/NMJI_1205_2023\/ref-7","doi-asserted-by":"publisher","first-page":"18","DOI":"10.4103\/ds.DS-D-22-00134","article-title":"Mortality and cause of death in patients with dermatologic diseases: An 11-year record-based observational study","volume":"41","author":"Saber","year":"2023","journal-title":"Dermatol Sin"},{"key":"10.25259\/NMJI_1205_2023\/ref-8","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1111\/j.1365-4632.2012.05818.x","article-title":"Inpatient dermatology: Profile of patients and characteristics of admissions to a tertiary dermatology inpatient unit in S\u00e3o Paulo, Brazil","volume":"53","author":"De Paula Samorano-Lima","year":"2014","journal-title":"Int J Dermatol"},{"key":"10.25259\/NMJI_1205_2023\/ref-9","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/j.annder.2012.10.591","article-title":"Changes in mortality in the Reims University Hospital Dermatology Department (1996-2009)","volume":"140","author":"Journet-Tollhupp","year":"2013","journal-title":"Ann Dermatol V\u00e9n\u00e9r\u00e9ol"},{"key":"10.25259\/NMJI_1205_2023\/ref-10","doi-asserted-by":"publisher","first-page":"S356","DOI":"10.1016\/j.annder.2014.09.297","article-title":"Morbidity and mortality in the dermatology department of the CHU of Conakry (Guinea)","volume":"141","author":"Keita","year":"2014","journal-title":"Ann Dermatol V\u00e9n\u00e9r\u00e9ol"},{"key":"10.25259\/NMJI_1205_2023\/ref-11","doi-asserted-by":"publisher","first-page":"56","DOI":"10.17140\/DRMTOJ-1-115","article-title":"Analysis of mortality in a dermatological affections referral center in Sub-Saharan Africa, Abidjan, R\u00e9publique de C\u00f4te d'Ivoire","volume":"1","author":"Ecra","year":"2016","journal-title":"Dermatol Open J"},{"key":"10.25259\/NMJI_1205_2023\/ref-12","doi-asserted-by":"publisher","first-page":"AB96","DOI":"10.1016\/j.jaad.2015.02.398","article-title":"Deaths and dermatology","volume":"72","author":"Gupta","year":"2015","journal-title":"J Am Acad Dermatol"},{"key":"10.25259\/NMJI_1205_2023\/ref-13","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1001\/archderm.145.1.67","article-title":"Twelve-year analysis of severe cases of drug reaction with eosinophilia and systemic symptoms: Acause of unpredictable multiorgan failure","volume":"145","author":"Eshki","year":"2009","journal-title":"Arch Dermatol"},{"key":"10.25259\/NMJI_1205_2023\/ref-14","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1007\/s10067-012-2152-8","article-title":"Leflunomide-induced DRESS syndrome with renal involvement and vasculitis","volume":"32","author":"Pinto","year":"2013","journal-title":"Clin Rheumatol"},{"key":"10.25259\/NMJI_1205_2023\/ref-15","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1016\/j.burns.2017.09.015","article-title":"Improving mortality outcomes of Stevens Johnson syndrome\/toxic epidermal necrolysis: A regional burns centre experience","volume":"44","author":"Nizamoglu","year":"2018","journal-title":"Burns"},{"key":"10.25259\/NMJI_1205_2023\/ref-16","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1016\/j.burns.2016.07.026","article-title":"Steven Johnson syndrome and toxic epidermal necrolysis in a burn unit: A15-year experience","volume":"43","author":"McCullough","year":"2017","journal-title":"Burns"},{"key":"10.25259\/NMJI_1205_2023\/ref-17","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1097\/00004630-200203000-00004","article-title":"A multicenter review of toxic epidermal necrolysis treated in U.S. Burn centers at the end of the twentieth century","volume":"23","author":"Palmieri","year":"2002","journal-title":"J Burn Care Rehabil"},{"key":"10.25259\/NMJI_1205_2023\/ref-18","doi-asserted-by":"publisher","first-page":"706","DOI":"10.4103\/0378-6323.116745","article-title":"Aretrospective study of mortality of pemphigus patients in a tertiary care hospital","volume":"79","author":"Nair","year":"2013","journal-title":"Indian J Dermatol Venereol Leprol"},{"key":"10.25259\/NMJI_1205_2023\/ref-19","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1111\/j.1365-4632.2004.02533.x","article-title":"Pemphigus in the Mediterranean region of Turkey: Astudy of 148cases","volume":"45","author":"Uzun","year":"2006","journal-title":"Int J Dermatol"},{"key":"10.25259\/NMJI_1205_2023\/ref-20","doi-asserted-by":"publisher","first-page":"906","DOI":"10.4103\/jcrt.JCRT_785_19","article-title":"Incidence of melanoma and nonmelanoma skin cancers in Indian and the global regions","volume":"17","author":"Labani","year":"2021","journal-title":"J Cancer Res Ther"}],"container-title":["The National Medical Journal of India"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/nmji.in\/mortality-in-dermatology-a-retrospective-study-of-cause-and-course\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/nmji.in\/mortality-in-dermatology-a-retrospective-study-of-cause-and-course\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T11:36:55Z","timestamp":1760009815000},"score":1,"resource":{"primary":{"URL":"https:\/\/nmji.in\/mortality-in-dermatology-a-retrospective-study-of-cause-and-course\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,18]]},"references-count":20,"alternative-id":["10.25259\/NMJI_1205_2023"],"URL":"https:\/\/doi.org\/10.25259\/nmji_1205_2023","relation":{},"ISSN":["2583-150X","0970-258X"],"issn-type":[{"type":"electronic","value":"2583-150X"},{"type":"print","value":"0970-258X"}],"subject":[],"published":{"date-parts":[[2025,9,18]]},"article-number":"203"}}