{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T02:34:28Z","timestamp":1780367668155,"version":"3.54.1"},"reference-count":17,"publisher":"Scientific Scholar","content-domain":{"domain":["nmji.in"],"crossmark-restriction":true},"short-container-title":["NMJI"],"abstract":"<jats:p>Right-sided endocarditis is a rare entity, with various series reporting an incidence of 5%\u201310%. Pulmonary valve (PV) is not only the least commonly involved valve in infective endocarditis (IE), with an incidence of 1.5%\u20132%, but \u2018isolated\u2019 pulmonic valve endocarditis (PVE) without tricuspid valve involvement is even rarer with limited published data. We report a middle-aged man with Noonan syndrome and a dysplastic PV with severe pulmonary stenosis. He presented with a large isolated mobile PV vegetation with moderate pulmonary regurgitation (PR). Initially, he was managed conservatively, but due to persistent fever, pulmonary regurgitation and evidence of pulmonary annular abscess extending into the right ventricular outflow tract, he required surgical intervention. Considering the low incidence of isolated PVE, it poses a challenge for physicians in prompt diagnosis and timely management of the infection.<\/jats:p>","DOI":"10.25259\/nmji_512_20","type":"journal-article","created":{"date-parts":[[2023,2,17]],"date-time":"2023-02-17T13:54:10Z","timestamp":1676642050000},"page":"281-283","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Isolated pulmonary valve endocarditis with pulmonary annular abscess in a patient of Noonan syndrome"],"prefix":"10.25259","volume":"35","author":[{"given":"SHIVANI","family":"RAO","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"PRAKASH CHAND","family":"NEGI","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2023,2,16]]},"reference":[{"key":"10.25259\/NMJI_512_20\/ref-1","doi-asserted-by":"publisher","first-page":"374","DOI":"10.1086\/313664","article-title":"Right-side endocarditis in injection drug users: Review of proposed mechanisms of pathogenesis","volume":"30","author":"Frontera","year":"2000","journal-title":"Clin Infect Dis"},{"key":"10.25259\/NMJI_512_20\/ref-2","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1001\/archinternmed.2008.603","article-title":"Clinical presentation, etiology, and outcome of infective endocarditis in the 21st century: The International Collaboration on Endocarditis-Prospective Cohort Study","volume":"169","author":"Murdoch","year":"2009","journal-title":"Arch Intern Med"},{"key":"10.25259\/NMJI_512_20\/ref-3","first-page":"1282","article-title":"Isolated pulmonic valve endocarditis in healthy hearts: A case report and review of the literature","volume":"16","author":"Ramadan","year":"2000","journal-title":"Can J Cardiol"},{"key":"10.25259\/NMJI_512_20\/ref-4","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1186\/1749-8090-3-46","article-title":"Pulmonary valve endocarditis caused by right ventricular outflow obstruction in association with sinus of Valsalva aneurysm: A case report","volume":"3","author":"Nishida","year":"2008","journal-title":"J Cardiothorac Surg"},{"key":"10.25259\/NMJI_512_20\/ref-5","doi-asserted-by":"publisher","first-page":"558","DOI":"10.1016\/0002-8703(85)90563-0","article-title":"Isolated pulmonic valve infective endocarditis: A diagnostically elusive entity","volume":"109","author":"Cassling","year":"1985","journal-title":"Am Heart J"},{"key":"10.25259\/NMJI_512_20\/ref-6","doi-asserted-by":"publisher","first-page":"480","DOI":"10.1136\/heart.89.5.480","article-title":"Pulmonary valve endocarditis","volume":"89","author":"Dhakam","year":"2003","journal-title":"Heart"},{"key":"10.25259\/NMJI_512_20\/ref-7","first-page":"125","article-title":"Infective endocarditis in intravenous drug abusers: Patterns of presentation and long-term outcomes of surgical treatment","volume":"15","author":"Carozza","year":"2006","journal-title":"J Heart Valve Dis"},{"key":"10.25259\/NMJI_512_20\/ref-8","doi-asserted-by":"publisher","first-page":"910","DOI":"10.1093\/infdis\/168.4.910","article-title":"Effect of thrombocytopenia on the early course of streptococcal endo-carditis","volume":"168","author":"Sullam","year":"1993","journal-title":"J Infect Dis"},{"key":"10.25259\/NMJI_512_20\/ref-9","first-page":"199","article-title":"Right-sided infective endocarditis: Recent epidemiologic changes","volume":"7","author":"Yuan","year":"2014","journal-title":"Int J Clin Exp Med"},{"key":"10.25259\/NMJI_512_20\/ref-10","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1186\/s12882-017-0706-3","article-title":"A chronic hemodialysis patient with isolated pulmonary valve infective endocarditis caused by non-albicans Candida: A rare case and literature review","volume":"18","author":"Chang","year":"2017","journal-title":"BMC Nephrol"},{"key":"10.25259\/NMJI_512_20\/ref-11","doi-asserted-by":"publisher","first-page":"2905","DOI":"10.1007\/s10096-012-1675-x","article-title":"Infective endocarditis in intravenous drug abusers: An update","volume":"31","author":"Sousa","year":"2012","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.25259\/NMJI_512_20\/ref-12","doi-asserted-by":"publisher","first-page":"560","DOI":"10.7326\/0003-4819-117-7-560","article-title":"Right-sided endocarditis in intravenous drug users. 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