{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T17:30:55Z","timestamp":1787679055389,"version":"build-2784847793"},"reference-count":14,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\n Background:<\/jats:title>\n The aim of this study is to highlight the importance of cryptococcosis as one of the most common fungal infections of the central nervous system, stressing the consideration of a cryptococcoma within the list of differential diagnosis of intraventricular masses in immunocompetent hosts.<\/jats:p>\n <\/jats:sec>\n \n Case Description:<\/jats:title>\n \n We present the case of an immunocompetent 41-year-old female from Philippines with an intraventricular cryptococcoma due to\n Cryptococcus neoformans<\/jats:italic>\n , mimicking an intraventricular primary brain tumor, who had hydrocephalus. She was approached as having a neoplastic lesion and underwent surgical resection plus third ventriculostomy through endoscopy. Later in her evolution, we realized the infectious nature of the lesion, and antifungal systemic therapy was initiated. In the end, she needed the placement of a ventriculoperitoneal shunt to maintain a good neurologic status. Despite all our efforts, she had a fatal outcome due to various complications.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n \n Our case is the first intraventricular cryptococcoma due to\n C. neoformans<\/jats:italic>\n , as far as we know, to be reported in English, German, or Spanish literature. Our report stresses the importance to consider this kind of infection in immunocompetent patients, to raise the level of suspicion of this diagnosis, and to know the complications and management options.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.25259\/sni-104-2019","type":"journal-article","created":{"date-parts":[[2019,8,23]],"date-time":"2019-08-23T12:47:57Z","timestamp":1566564477000},"page":"115","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Intraventricular cryptococcoma mimicking a neoplastic lesion in an immunocompetent patient with hydrocephalus: A case report"],"prefix":"10.25259","volume":"10","author":[{"given":"Xavier A.","family":"Santander","sequence":"first","affiliation":[{"name":"Departments of Neurosurgery,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raquel","family":"Guti\u00e9rrez-Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Cot\u00faa","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Tejerina","sequence":"additional","affiliation":[{"name":"Departments of Pathology, University Hospital Puerta de Hierro Majadahonda, Madrid, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregorio-Boto","family":"Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery,"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2019,6,25]]},"reference":[{"key":"10.25259\/SNI-104-2019\/ref-1","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1080\/02688690310001611242","article-title":"Surgical treatment of intracranial hypertension in encephalic cryptococcosis","volume":"17","author":"Calvo","year":"2003","journal-title":"Br J Neurosurg"},{"key":"10.25259\/SNI-104-2019\/ref-2","first-page":"99","article-title":"Epidemiologic study of cryptococcosis in Spain: First results","volume":"18","author":"Colom-Valiente","year":"2001","journal-title":"Rev Iberoam Micol"},{"key":"10.25259\/SNI-104-2019\/ref-3","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1590\/0037-8682-0176-2013","article-title":"Ventriculoperitoneal shunts for treating increased intracranial pressure in cryptococcal meningitis with or without ventriculomegaly","volume":"47","author":"Corti","year":"2004","journal-title":"Rev Soc Bras Med Trop"},{"key":"10.25259\/SNI-104-2019\/ref-4","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/j.surneu.2004.04.020","article-title":"Intracranial fungal granuloma: Analysis of 40 patients and review of the literature","volume":"63","author":"Dubey","year":"2005","journal-title":"Surg Neurol"},{"key":"10.25259\/SNI-104-2019\/ref-5","doi-asserted-by":"crossref","first-page":"1642","DOI":"10.1128\/JCM.28.7.1642-1644.1990","article-title":"Natural habitat of Cryptococcus neoformans var. Gattii","volume":"28","author":"Ellis","year":"1990","journal-title":"J Clin Microbiol"},{"key":"10.25259\/SNI-104-2019\/ref-6","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1093\/cid\/cir723","article-title":"Cryptococcus gattii in the United States: Clinical aspects of infection with an emerging pathogen","volume":"53","author":"Harris","year":"2011","journal-title":"Clin Infect Dis"},{"key":"10.25259\/SNI-104-2019\/ref-7","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/s00701-009-0311-8","article-title":"Central nervous system cryptococcoma in immunocompetent patients: A short review illustrated by a new case","volume":"152","author":"Li","year":"2010","journal-title":"Acta Neurochir"},{"key":"10.25259\/SNI-104-2019\/ref-8","doi-asserted-by":"crossref","first-page":"327","DOI":"10.5582\/bst.2014.01070","article-title":"The use of ventriculoperitoneal shunts for uncontrollable intracranial hypertension in patients with HIV-associated cryptococcal meningitis with or without hydrocephalus","volume":"8","author":"Liu","year":"2014","journal-title":"Biosci Trends"},{"key":"10.25259\/SNI-104-2019\/ref-9","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1016\/j.wneu.2015.01.053","article-title":"Intracranial fungal granulomas: A single institutional clinicopathologic study of 66 patients and review of the literature","volume":"83","author":"Naik","year":"2015","journal-title":"World Neurosurg"},{"key":"10.25259\/SNI-104-2019\/ref-10","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1590\/S0036-46652007000400014","article-title":"Cryptococcus gattii fungemia: Report of a case with lung and brain lesions mimicking radiological features of malignancy","volume":"49","author":"Oliveira","year":"2007","journal-title":"Rev Inst Med Trop Sao Paulo"},{"key":"10.25259\/SNI-104-2019\/ref-11","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1086\/649858","article-title":"Clinical practice guidelines for the management of cryptococcal disease: 2010 update by the Infectious Diseases Society of America","volume":"50","author":"Perfect","year":"2010","journal-title":"Clin Infect Dis"},{"key":"10.25259\/SNI-104-2019\/ref-12","doi-asserted-by":"crossref","first-page":"603","DOI":"10.2214\/ajr.154.3.2106227","article-title":"CT of intracranial cryptococcosis","volume":"154","author":"Popovich","year":"1990","journal-title":"Am J Roentgenol"},{"key":"10.25259\/SNI-104-2019\/ref-13","first-page":"218824","article-title":"Cerebral cryptococcoma mimicking glioblastoma","volume":"2017","author":"Ulett","year":"2017","journal-title":"BMJ Case Rep"},{"key":"10.25259\/SNI-104-2019\/ref-14","doi-asserted-by":"crossref","first-page":"2387","DOI":"10.2169\/internalmedicine.52.0613","article-title":"Central nervous system infection caused by Cryptococcus","volume":"52","author":"Yeh","year":"2013","journal-title":"Intern Med"}],"container-title":["Surgical Neurology International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/surgicalneurologyint.com\/intraventricular-cryptococcoma-mimicking-a-neoplastic-lesion-in-an-immunocompetent-patient-with-hydrocephalus-a-case-report\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/intraventricular-cryptococcoma-mimicking-a-neoplastic-lesion-in-an-immunocompetent-patient-with-hydrocephalus-a-case-report\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,17]],"date-time":"2021-01-17T04:44:37Z","timestamp":1610858677000},"score":1,"resource":{"primary":{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/intraventricular-cryptococcoma-mimicking-a-neoplastic-lesion-in-an-immunocompetent-patient-with-hydrocephalus-a-case-report\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,25]]},"references-count":14,"alternative-id":["10.25259\/SNI-104-2019"],"URL":"https:\/\/doi.org\/10.25259\/sni-104-2019","relation":{},"ISSN":["2152-7806"],"issn-type":[{"value":"2152-7806","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6,25]]},"article-number":"115"}}