{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T22:38:23Z","timestamp":1775860703593,"version":"3.50.1"},"reference-count":36,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\nBackground:<\/jats:title>\nThe current study aimed to assess the role of microsurgical treatment of patients with supratentorial cavernoma with epilepsy based on analysis of our patients.<\/jats:p>\n<\/jats:sec>\n\nMethods:<\/jats:title>\nThis retrospective study included 23 patients with supratentorial cavernoma on computed tomography (CT) scan and magnetic resonance imaging (MRI) of the brain admitted to the Department of Neurosurgery, Assiut University Hospitals (single tertiary hospital) between January 2014 and January 2018 (minimum 12-month follow-up). Deep-seated hemispheric and multiple cavernomas were excluded. Radiographs and hospital data of the patients were gathered and analyzed. All patients underwent the surgical procedure by one experienced neurosurgeon and the diagnosis was confirmed by pathologic evaluation.<\/jats:p>\n<\/jats:sec>\n\nResults:<\/jats:title>\nA total of 23 patients underwent surgical intervention consist of 15 (65%) men and 8 (35%) women. Their age varies from 11 to 59 year with an average of 36.6 years. All patients presented with seizure. The supratentorial cavernomas were located commonly in temporal lobes; 9 patients (39.1%). 19 (83%) of cavernoma located in the left side. 18 (78%) of cavernoma had a size <2 cavernoma. Complete excision was confirmed in postoperative investigations (CT and MRI brain images). All 10 patients with only one seizure preoperatively were seizure free at follow-up. Of nine patients who had experienced between two and five seizures preoperatively, 7 (78%) were seizure free, and of four patients with numerous seizures preoperatively, 3 (75%) were seizure free.<\/jats:p>\n<\/jats:sec>\n\nConclusion:<\/jats:title>\nOur retrospective population study demonstrates an insight into the supratentorial cavernoma and suggests that microsurgical removal of the symptomatic cavernoma is generally accepted as the most effective and safe method.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni-178-2019","type":"journal-article","created":{"date-parts":[[2019,8,25]],"date-time":"2019-08-25T11:55:34Z","timestamp":1566734134000},"page":"117","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Supratentorial cavernoma and epilepsy: Experience with 23 cases and literature review"],"prefix":"10.25259","volume":"10","author":[{"given":"Mohamed","family":"Khallaf","sequence":"first","affiliation":[{"name":"Department of Neurosurgery,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"Abdelrahman","sequence":"additional","affiliation":[{"name":"Department of Neurology, Faculty of Medicine, Assiut University, Assiut, Egypt."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2019,6,25]]},"reference":[{"key":"10.25259\/SNI-178-2019\/ref-1","doi-asserted-by":"crossref","first-page":"1589","DOI":"10.1227\/NEU.0b013e3181f8d1b2","article-title":"Cavernous malformations of the brainstem presenting in childhood: Surgical experience in 40 patients","volume":"67","author":"Abla","year":"2010","journal-title":"Neurosurgery"},{"key":"10.25259\/SNI-178-2019\/ref-2","doi-asserted-by":"crossref","first-page":"e7","DOI":"10.3171\/foc.2006.21.1.8","article-title":"Cerebral cavernous malformations and epilepsy","volume":"21","author":"Awad","year":"2006","journal-title":"Neurosurg Focus"},{"key":"10.25259\/SNI-178-2019\/ref-3","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1038\/nrneurol.2009.177","article-title":"Cavernous malformations: Natural history, diagnosis and treatment","volume":"5","author":"Batra","year":"2009","journal-title":"Nat Rev Neurol"},{"key":"10.25259\/SNI-178-2019\/ref-4","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1111\/j.1528-1167.2006.00941.x","article-title":"Seizure outcome after resection of supratentorial cavernous malformations: A study of 168 patients","volume":"48","author":"Baumann","year":"2007","journal-title":"Epilepsia"},{"key":"10.25259\/SNI-178-2019\/ref-5","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1111\/j.1528-1167.2006.00468.x","article-title":"Seizure outcome after resection of cavernous malformations is better when surrounding hemosiderin-stained brain also is removed","volume":"47","author":"Baumann","year":"2006","journal-title":"Epilepsia"},{"key":"10.25259\/SNI-178-2019\/ref-6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s101430100179","article-title":"Cerebral cavernomas in the adult. 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