{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T12:19:14Z","timestamp":1773922754263,"version":"3.50.1"},"reference-count":22,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\">\n<jats:title>Background: <\/jats:title>\n<jats:p>Myxopapillary ependimoma (MPE) is a benign slow-growing tumor, and it has been designated histologically as a Grade I neoplasm according to the 2016 World Health Organization classification. Despite the benign character, dissemination and metastasis have occasionally been reported. The retrograde dissemination to other levels of the neuraxis is extremely rare, being more frequent to the intracranial compartment.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st2\">\n<jats:title>Case Description: <\/jats:title>\n<jats:p>We hereby present a case of medullary metastasis of cauda equina MPE, with a history of having undergone a subtotal resection and postoperative adjuvant radiotherapy. The patient presents complaints of night dorsal pain attributable to intradural metastasis twenty-one years after the first surgical intervention.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st3\">\n<jats:title>Conclusion: <\/jats:title>\n<jats:p>The case reported highlights the importance of long follow-up in patients with MPE, since the possibility of secondary seeding to distant craniospinal sites or local spinal sites after surgery, and radiotherapy should be considered in metastatic disease.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni-96-2019","type":"journal-article","created":{"date-parts":[[2019,8,25]],"date-time":"2019-08-25T08:02:34Z","timestamp":1566720154000},"page":"83","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["A rare case of an intramedullary metastasis of a myxopapillary ependymoma"],"prefix":"10.25259","volume":"10","author":[{"given":"Lino","family":"Fonseca","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Centro Hospitalar Lisboa Central-Hospital S\u00e3o Jos\u00e9, Serrano, Lisboa, Portugal, Barcelona, Spain."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Cicuendez","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Hospital Universitari Vall d\u2019Hebron, Barcelona, Spain."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco","family":"Mart\u00ednez-Ricarte","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Hospital Universitari Vall d\u2019Hebron, Barcelona, Spain."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Mart\u00ednez-Saez","sequence":"additional","affiliation":[{"name":"Department of Pathology, Hospital Universitari Vall d\u2019Hebron, Barcelona, Spain."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esteban","family":"Cordero","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Hospital Universitari Vall d\u2019Hebron, Barcelona, Spain."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agust\u00edn","family":"Bescos","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Hospital Universitari Vall d\u2019Hebron, Barcelona, Spain."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2019,5,10]]},"reference":[{"key":"10.25259\/SNI-96-2019\/ref-1","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1111\/j.1365-2559.2004.02009.x","article-title":"Metastasizing myxopapillary ependymoma","volume":"46","author":"Al-Hussaini","year":"2005","journal-title":"Histopathology"},{"key":"10.25259\/SNI-96-2019\/ref-2","doi-asserted-by":"crossref","first-page":"68","DOI":"10.4184\/asj.2011.5.1.68","article-title":"Multi-focal myxopapillary ependymoma in the lumbar and sacral regions requiring cranio-spinal radiation therapy: A case report","volume":"5","author":"Andoh","year":"2011","journal-title":"Asian Spine J"},{"key":"10.25259\/SNI-96-2019\/ref-3","doi-asserted-by":"crossref","first-page":"40","DOI":"10.17305\/bjbms.2009.2755","article-title":"Extramedullary intradural spinal tumors: A review of modern diagnostic and treatment options and a report of a series","volume":"9","author":"Arnautovic","year":"2009","journal-title":"Bosn J Basic Med Sci"},{"key":"10.25259\/SNI-96-2019\/ref-4","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1007\/s10143-009-0190-8","article-title":"Long term outcomes following surgical resection of myxopapillary ependymomas","volume":"32","author":"Bagley","year":"2009","journal-title":"Neurosurg Rev"},{"key":"10.25259\/SNI-96-2019\/ref-5","doi-asserted-by":"crossref","first-page":"5404","DOI":"10.4081\/rt.2014.5404","article-title":"Spinal drop metastasis in myxopapillary ependymoma: A case report and a review of treatment options","volume":"6","author":"Bates","year":"2014","journal-title":"Rare Tumors"},{"key":"10.25259\/SNI-96-2019\/ref-6","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1007\/s11060-016-2135-8","article-title":"Spinal cord ependymoma: A review of the literature and case series of ten patients","volume":"128","author":"Celano","year":"2016","journal-title":"J Neurooncol"},{"key":"10.25259\/SNI-96-2019\/ref-7","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/s10014-011-0059-8","article-title":"Primary myxopapillary ependymoma of the fourth ventricle with cartilaginous metaplasia: A case report and review of the literature","volume":"29","author":"Chakraborti","year":"2012","journal-title":"Brain Tumor Pathol"},{"key":"10.25259\/SNI-96-2019\/ref-8","first-page":"87","article-title":"Concomitant localization of a myxopapillary ependymoma at the middle thoracic part of the spinal cord and at the distal part of the filum terminale. 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