{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T14:49:13Z","timestamp":1785422953943,"version":"3.56.0"},"reference-count":36,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\">\n<jats:title>Background<\/jats:title>\n<jats:p>Chronic subdural hematomas (cSDHs), blood collections under the dural layer of the brain, are common in the elderly and frequently linked to trauma and anticoagulation. As the global elderly population increases, the incidence of cSDH is expected to rise, straining healthcare systems. Middle meningeal artery embolization is a minimally invasive alternative to surgery, which could prove especially beneficial for elderly patients with multiple comorbidities or contraindications to surgery. However, the efficacy and patient-related outcomes associated with different embolization materials remain unknown.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st2\">\n<jats:title>Methods<\/jats:title>\n<jats:p>The authors conducted a scoping review of manuscripts published through August 2023 to assess outcomes associated with various embolization materials used in middle meningeal artery embolization for cSDH. Recurrence rates after embolization and complications were the primary outcomes.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st3\">\n<jats:title>Results<\/jats:title>\n<jats:p>The authors analyzed a total of 25 studies, reporting 1579 embolizations in 1362 patients. Embolic materials included particles (35.7%), liquid embolisates (31.5%), coils (3.2%), and combinations of the aforementioned materials (29.6%). Recurrence rates were low (5.1%), and the most common complications were seizures and strokes. The overall mortality was 1.4%, with three procedure-related deaths.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st4\">\n<jats:title>Conclusion<\/jats:title>\n<jats:p>With low recurrence and complication rates, middle meningeal artery embolization is a safe and effective treatment for cSDH. However, due to limitations in data availability, we were not able to link hematoma recurrence or complication rates with the type of embolization material used. To better understand the safety profiles of different materials, further large-scale studies are warranted.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_1003_2024","type":"journal-article","created":{"date-parts":[[2025,3,14]],"date-time":"2025-03-14T01:54:39Z","timestamp":1741917279000},"page":"88","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Middle meningeal artery embolization: A scoping review of trends and outcomes by embolization material"],"prefix":"10.25259","volume":"16","author":[{"given":"Tiffany","family":"Chu","sequence":"first","affiliation":[{"name":"Department of Neurologic Surgery, Creighton University School of Medicine, Omaha, Nebraska, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan","family":"Sindewald","sequence":"additional","affiliation":[{"name":"Department of Neurologic Surgery, University of California San Diego School of Medicine, La Jolla, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren E.","family":"Stone","sequence":"additional","affiliation":[{"name":"Department of Neurologic Surgery, University of California San Diego, La Jolla, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arvin R.","family":"Wali","sequence":"additional","affiliation":[{"name":"Department of Neurologic Surgery, University of California San Diego, La Jolla, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Santiago-Dieppa","sequence":"additional","affiliation":[{"name":"Department of Neurologic Surgery, University of California San Diego, La Jolla, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2025,3,14]]},"reference":[{"key":"10.25259\/SNI_1003_2024\/ref-1","doi-asserted-by":"crossref","first-page":"916","DOI":"10.3174\/ajnr.A7077","article-title":"Middle meningeal artery embolization using combined particle embolization and n-BCA with the dextrose 5% in water push technique for chronic subdural hematomas: A prospective safety and feasibility study","volume":"42","author":"Al-Mufti","year":"2021","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.25259\/SNI_1003_2024\/ref-2","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/s10143-004-0337-6","article-title":"Demographics and prevalent risk factors of chronic subdural haematoma: Results of a large single-center cohort study","volume":"27","author":"Baechli","year":"2004","journal-title":"Neurosurg Rev"},{"key":"10.25259\/SNI_1003_2024\/ref-3","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1148\/radiol.2017170053","article-title":"Middle meningeal artery embolization for chronic subdural hematoma","volume":"286","author":"Ban","year":"2018","journal-title":"Radiology"},{"key":"10.25259\/SNI_1003_2024\/ref-4","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1111\/ane.13518","article-title":"Presenting symptoms and functional outcome of chronic subdural hematoma patients","volume":"145","author":"Blaauw","year":"2022","journal-title":"Acta Neurol Scand"},{"key":"10.25259\/SNI_1003_2024\/ref-5","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1136\/neurintsurg-2020-016552","article-title":"Middle meningeal artery embolization for chronic subdural hematoma: An institutional technical analysis","volume":"13","author":"Catapano","year":"2021","journal-title":"J Neurointerv Surg"},{"key":"10.25259\/SNI_1003_2024\/ref-6","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1136\/neurintsurg-2021-017352","article-title":"Middle meningeal artery embolization for chronic subdural hematoma: A systematic review and meta-analysis","volume":"13","author":"Ironside","year":"2021","journal-title":"J Neurointerv Surg"},{"key":"10.25259\/SNI_1003_2024\/ref-7","doi-asserted-by":"crossref","first-page":"15910199231217144","DOI":"10.1177\/15910199231217144","article-title":"Coil embolization alone appears sufficient for middle meningeal artery embolization","author":"Iyer","year":"2023","journal-title":"Interv Neuroradiol"},{"key":"10.25259\/SNI_1003_2024\/ref-8","first-page":"1","article-title":"Efficacy of middle meningeal artery embolization for organized chronic subdural hematoma","volume":"13","author":"Izawa","year":"2019","journal-title":"J Neuroendovasc Ther"},{"key":"10.25259\/SNI_1003_2024\/ref-9","doi-asserted-by":"crossref","first-page":"E5","DOI":"10.3171\/2020.7.FOCUS20518","article-title":"Middle meningeal artery embolization treatment of nonacute subdural hematomas in the elderly: A multiinstitutional experience of 151 cases","volume":"49","author":"Joyce","year":"2020","journal-title":"Neurosurg Focus"},{"key":"10.25259\/SNI_1003_2024\/ref-10","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1093\/neuros\/nyaa379","article-title":"Middle meningeal artery embolization for chronic subdural hematoma: A multi-center experience of 154 consecutive embolizations","volume":"88","author":"Kan","year":"2021","journal-title":"Neurosurgery"},{"key":"10.25259\/SNI_1003_2024\/ref-11","doi-asserted-by":"crossref","first-page":"e581","DOI":"10.1016\/j.wneu.2022.06.099","article-title":"Middle meningeal artery embolization with isolated use of coils for treatment of chronic subdural hematomas: A case series","volume":"165","author":"Khorasanizadeh","year":"2022","journal-title":"World Neurosurg"},{"key":"10.25259\/SNI_1003_2024\/ref-12","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1016\/j.wneu.2017.02.070","article-title":"Embolization therapy for refractory hemorrhage in patients with chronic subdural hematomas","volume":"101","author":"Kim","year":"2017","journal-title":"World Neurosurg"},{"key":"10.25259\/SNI_1003_2024\/ref-13","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1038\/nrneurol.2014.163","article-title":"Chronic subdural haematoma: Modern management and emerging therapies","volume":"10","author":"Kolias","year":"2014","journal-title":"Nat Rev Neurol"},{"key":"10.25259\/SNI_1003_2024\/ref-14","doi-asserted-by":"crossref","first-page":"e27","DOI":"10.1016\/j.wneu.2023.01.077","article-title":"Outcomes of particle versus liquid embolic materials used in middle meningeal artery embolization for the treatment of chronic subdural hematoma","volume":"173","author":"Krothapalli","year":"2023","journal-title":"World Neurosurg"},{"key":"10.25259\/SNI_1003_2024\/ref-15","doi-asserted-by":"crossref","first-page":"297","DOI":"10.3174\/ajnr.A7796","article-title":"Embolic agent choice in middle meningeal artery embolization as primary or adjunct treatment for chronic subdural hematoma: A systematic review and meta-analysis","volume":"44","author":"Ku","year":"2023","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.25259\/SNI_1003_2024\/ref-16","doi-asserted-by":"crossref","first-page":"168","DOI":"10.25259\/SNI_208_2023","article-title":"The efficacy of postoperative middle meningeal artery embolization on chronic subdural hematoma-A multicentered randomized controlled trial","volume":"14","author":"Lam","year":"2023","journal-title":"Surg Neurol Int"},{"key":"10.25259\/SNI_1003_2024\/ref-17","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1093\/neuros\/nyy521","article-title":"Middle meningeal artery embolization for chronic subdural hematoma: A series of 60 cases","volume":"85","author":"Link","year":"2019","journal-title":"Clin Neurosurg"},{"key":"10.25259\/SNI_1003_2024\/ref-18","doi-asserted-by":"crossref","first-page":"e6","DOI":"10.1016\/j.wneu.2023.03.050","article-title":"Time and influencing factors to chronic subdural hematoma resolution after middle meningeal artery embolization","volume":"179","author":"Liu","year":"2023","journal-title":"World Neurosurg"},{"key":"10.25259\/SNI_1003_2024\/ref-19","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1227\/neu.0000000000001882","article-title":"Middle meningeal artery embolization for chronic subdural hematoma using N-butyl cyanoacrylate with D5W push technique","volume":"90","author":"Majidi","year":"2022","journal-title":"Neurosurgery"},{"key":"10.25259\/SNI_1003_2024\/ref-20","doi-asserted-by":"crossref","first-page":"686","DOI":"10.3171\/jns.2000.93.4.0686","article-title":"Middle meningeal artery embolization for refractory chronic subdural hematoma. Case report","volume":"93","author":"Mandai","year":"2000","journal-title":"J Neurosurg"},{"key":"10.25259\/SNI_1003_2024\/ref-21","first-page":"e39733","article-title":"Revolutionizing treatment for chronic subdural hematoma: Promising outcomes with middle meningeal artery embolization","volume":"15","author":"Msheik","year":"2023","journal-title":"Cureus"},{"key":"10.25259\/SNI_1003_2024\/ref-22","doi-asserted-by":"crossref","first-page":"e166","DOI":"10.1016\/j.wneu.2020.05.060","article-title":"Increases in subdural hematoma with an aging population-the future of American cerebrovascular disease","volume":"141","author":"Neifert","year":"2020","journal-title":"World Neurosurg"},{"key":"10.25259\/SNI_1003_2024\/ref-23","doi-asserted-by":"crossref","first-page":"e671","DOI":"10.1016\/j.wneu.2019.02.121","article-title":"Midterm follow-up of patients with middle meningeal artery embolization in intractable chronic subdural hematoma","volume":"126","author":"Okuma","year":"2019","journal-title":"World Neurosurg"},{"key":"10.25259\/SNI_1003_2024\/ref-24","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1136\/neurintsurg-2020-016185","article-title":"Transradial middle meningeal artery embolization for chronic subdural hematoma using Onyx: case series","volume":"12","author":"Rajah","year":"2020","journal-title":"J Neurointerv Surg"},{"key":"10.25259\/SNI_1003_2024\/ref-25","doi-asserted-by":"crossref","first-page":"2033","DOI":"10.1007\/s00701-020-04398-3","article-title":"Chronic subdural hematoma-incidence, complications, and financial impact","volume":"162","author":"Rauhala","year":"2020","journal-title":"Acta Neurochir (Wien)"},{"key":"10.25259\/SNI_1003_2024\/ref-26","doi-asserted-by":"crossref","first-page":"105","DOI":"10.2176\/nmccrj.cr.2018-0275","article-title":"Angiogenesis in the septum and inner membrane of refractory chronic subdural hematomas: Consideration of findings after middle meningeal artery embolization with low-concentration n-butyl-2-cyanoacrylate","volume":"6","author":"Saito","year":"2019","journal-title":"NMC Case Rep J"},{"key":"10.25259\/SNI_1003_2024\/ref-27","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1227\/neu.0000000000002038","article-title":"The \u201cbright falx\u201d sign-midline embolic penetration is associated with faster resolution of chronic subdural hematoma after middle meningeal artery embolization: A case series","volume":"91","author":"Samarage","year":"2022","journal-title":"Neurosurgery"},{"key":"10.25259\/SNI_1003_2024\/ref-28","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.3171\/2020.10.JNS202856","article-title":"Perioperative prophylactic middle meningeal artery embolization for chronic subdural hematoma: A series of 44 cases","volume":"135","author":"Schwarz","year":"2021","journal-title":"J Neurosurg"},{"key":"10.25259\/SNI_1003_2024\/ref-29","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1177\/15910199221104631","article-title":"Radiographic and clinical outcomes with particle or liquid embolic agents for middle meningeal artery embolization of nonacute subdural hematomas","volume":"29","author":"Scoville","year":"2023","journal-title":"Interv Neuroradiol"},{"key":"10.25259\/SNI_1003_2024\/ref-30","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1227\/neu.0000000000002307","article-title":"Onyx versus particles for middle meningeal artery embolization in chronic subdural hematoma","volume":"92","author":"Shehabeldin","year":"2023","journal-title":"Neurosurgery"},{"key":"10.25259\/SNI_1003_2024\/ref-31","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1136\/neurintsurg-2020-016048","article-title":"Middle meningeal artery embolization reduces the post-operative recurrence rate of at-risk chronic subdural hematoma","volume":"12","author":"Shotar","year":"2020","journal-title":"J Neurointerv Surg"},{"key":"10.25259\/SNI_1003_2024\/ref-32","doi-asserted-by":"crossref","first-page":"CASE24192","DOI":"10.3171\/CASE24192","article-title":"Simultaneous resolution of arachnoid cyst and chronic subdural hematoma after middle meningeal artery embolization: Illustrative case","volume":"8","author":"Sindewald","year":"2024","journal-title":"J Neurosurg Case Lessons"},{"key":"10.25259\/SNI_1003_2024\/ref-33","doi-asserted-by":"crossref","first-page":"402","DOI":"10.2176\/nmc.ra.2016-0337","article-title":"Chronic subdural hematoma in elderly patients: Is this disease benign?","volume":"57","author":"Uno","year":"2017","journal-title":"Neurol Med Chir (Tokyo)"},{"key":"10.25259\/SNI_1003_2024\/ref-34","doi-asserted-by":"crossref","first-page":"214","DOI":"10.7461\/jcen.2023.E2022.08.001","article-title":"Helical coils augment embolization of the middle meningeal artery for treatment of chronic subdural hematoma: A technical note","volume":"25","author":"Wali","year":"2023","journal-title":"J Cerebrovasc Endovasc Neurosurg"},{"key":"10.25259\/SNI_1003_2024\/ref-35","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.wneu.2019.02.208","article-title":"Safety and effectiveness of embolization for chronic subdural hematoma: Systematic review and case series","volume":"126","author":"Waqas","year":"2019","journal-title":"World Neurosurg"},{"key":"10.25259\/SNI_1003_2024\/ref-36","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.hest.2022.04.004","article-title":"Middle meningeal embolization for chronic subdural Hematoma: A case series of 7 patients and review of time course of resolution","volume":"4","author":"Wong","year":"2023","journal-title":"Brain Hemorrhages"}],"container-title":["Surgical Neurology International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/surgicalneurologyint.com\/middle-meningeal-artery-embolization-a-scoping-review-of-trends-and-outcomes-by-embolization-material\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/middle-meningeal-artery-embolization-a-scoping-review-of-trends-and-outcomes-by-embolization-material\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,14]],"date-time":"2025-03-14T01:54:57Z","timestamp":1741917297000},"score":1,"resource":{"primary":{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/middle-meningeal-artery-embolization-a-scoping-review-of-trends-and-outcomes-by-embolization-material\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,14]]},"references-count":36,"alternative-id":["10.25259\/SNI_1003_2024"],"URL":"https:\/\/doi.org\/10.25259\/sni_1003_2024","relation":{},"ISSN":["2152-7806","2229-5097"],"issn-type":[{"value":"2152-7806","type":"electronic"},{"value":"2229-5097","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3,14]]},"article-number":"88"}}