{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,23]],"date-time":"2023-10-23T12:02:19Z","timestamp":1698062539291},"reference-count":9,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\nBackground: <\/jats:title>\nMegalencephaly-capillary malformation (M-CM) syndrome is a rare overgrowth syndrome characterized by macrocephaly, port-wine stains, asymmetric brain growth, hydrocephalus, and developmental delay. Cerebellar tonsil herniation is often seen, but rarely with syringomyelia.<\/jats:p>\n<\/jats:sec>\n\nCase Description: <\/jats:title>\nA newborn with M-CM syndrome developed a progressive Chiari malformation type I (CM-I) with syringomyelia. At 4 months, he was treated for subdural hematomas, while at 10 months, he required a shunt for hydrocephalus. At 16 years of age, he newly presented a left hemiparesis and ataxia. Notably, successive volumetric measurements of the posterior fossa\/cerebellum showed disproportionate cerebellar growth over time that correlated with the appearance of a CM-I. Following a suboccipital craniectomy with C1-laminectomy and duraplasty, he neurologically improved.<\/jats:p>\n<\/jats:sec>\n\nConclusion: <\/jats:title>\nM-CM with CM-I and syringomyelia rarely present together. Here, we treated an infant with M-CM who developed a progressive CM-I malformation and syringomyelia reflecting disproportionate growth of the cerebellum\/posterior fossa over a 16-year period.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_1016_2021","type":"journal-article","created":{"date-parts":[[2022,5,20]],"date-time":"2022-05-20T12:44:38Z","timestamp":1653050678000},"page":"211","update-policy":"http:\/\/dx.doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Brain overgrowth associated with megalencephaly-capillary malformation syndrome causing progressive Chiari and syringomyelia"],"prefix":"10.25259","volume":"13","author":[{"given":"Tom","family":"Deleu","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, University Hospitals Leuven, Leuven, Belgium."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katrien","family":"Jansen","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University Hospitals Leuven, Leuven, Belgium."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank Van","family":"Calenbergh","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University Hospitals Leuven, Leuven, Belgium."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2022,5,20]]},"reference":[{"key":"10.25259\/SNI_1016_2021\/ref-1","doi-asserted-by":"crossref","first-page":"161","DOI":"10.3171\/2014.10.PEDS14295","article-title":"Pediatric and adult Chiari malformation Type I surgical series 1965-2013: A review of demographics, operative treatment, and outcomes","volume":"15","author":"Arnautovic","year":"2015","journal-title":"J Neurosurg Pediatr"},{"key":"10.25259\/SNI_1016_2021\/ref-2","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1097\/00019605-199710000-00001","article-title":"Macrocephaly with cutis marmorata, haemangioma and syndactyly a distinctive overgrowth 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