{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T10:31:01Z","timestamp":1767349861307,"version":"3.48.0"},"reference-count":29,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\n Background:<\/jats:title>\n \n Cerebral sparganosis is a rare parasitic infection of the central nervous system caused by the plerocercoid larva of\n Spirometra<\/jats:italic>\n species. A hallmark of the disease is the dynamic migratory behavior of the parasite within the brain, often resulting in progressive neurological symptoms and shifting radiologic features. While most cases are diagnosed within a few years of symptom onset, chronic cases spanning more than a decade are exceedingly rare. Understanding long-term imaging evolution, migratory patterns, and treatment strategies in these rare cases is crucial for optimal management.\n <\/jats:p>\n <\/jats:sec>\n \n Case Description:<\/jats:title>\n We report a rare case of cerebral sparganosis with an exceptionally prolonged disease course of 19 years. The patient initially presented with seizures and underwent a stereotactic brain biopsy; however, a definitive diagnosis could not be established at that time. Serial magnetic resonance imaging revealed a unique and extensive intracerebral migratory pattern, including deep-seated and eloquent areas. Eventually, the parasite migrated to a surgically accessible cortical location, allowing for successful resection. Histopathology confirmed a degenerated Sparganum larva surrounded by chronic inflammation. A schematic diagram was created to illustrate the complex migratory pathway. A literature review of cases lasting \u226510 years was also conducted, highlighting the parasite\u2019s exceptional longevity and treatment outcomes.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n This case highlights the remarkable ability of Sparganum larvae to survive within human brain tissue for nearly two decades, with evidence of active intracerebral migration. Surgical excision remains the most definitive and effective treatment approach. Due to the potential for delayed diagnosis and chronic progression, long-term imaging follow-up and continued clinical awareness are essential for early recognition and successful management, even in regions where sparganosis is not commonly encountered.<\/jats:p>\n <\/jats:sec>","DOI":"10.25259\/sni_1041_2025","type":"journal-article","created":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T09:56:10Z","timestamp":1766742970000},"page":"550","update-policy":"https:\/\/doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A hidden traveler in the brain: A 19-year odyssey of migratory cerebral sparganosis"],"prefix":"10.25259","volume":"16","author":[{"given":"Prasert","family":"Iampreechakul","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Neurological Institute of Thailand, Bangkok, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chonlada","family":"Angsusing","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, Neurological Institute of Thailand, Bangkok, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sunisa","family":"Hangsapruek","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, Neurological Institute of Thailand, Bangkok, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Punjama","family":"Lertbutsayanukul","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, Neurological Institute of Thailand, Bangkok, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thananan","family":"Phothi","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, Neurological Institute of Thailand, Bangkok, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samasuk","family":"Thammachantha","sequence":"additional","affiliation":[{"name":"Department of Pathology, Neurological Institute of Thailand, Bangkok, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adisak","family":"Tanpun","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Neurosurgery, Phrapokklao Hospital, Chanthaburi, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ratirath","family":"Samol","sequence":"additional","affiliation":[{"name":"Department of Pathology, Sawanpracharak Hospital, Nakhon Sawan, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ekkarong","family":"Suwanwech","sequence":"additional","affiliation":[{"name":"Department of Surgery, Sawanpracharak Hospital, Nakhon Sawan, 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