{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T16:41:18Z","timestamp":1649090478785},"reference-count":6,"publisher":"Scientific Scholar","content-domain":{"domain":["surgicalneurologyint.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\">\n<jats:title>Background: <\/jats:title>\n<jats:p>A depressed host defense is a major contributor to the oral shedding of herpes simplex virus (HSV) type 1. Here, we present an instance in which herpes simplex labialis was reactivated following major spinal deformity surgery.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st2\">\n<jats:title>Case Description: <\/jats:title>\n<jats:p>A 59-year-old female underwent spinal deformity correction for lumbar degenerative scoliosis. On postoperative days 2\u20133, she presented with pyrexia (38\u00b0C) and tachycardia (94\/min); by day 5 she had multiple ulcers around her lips and was HSV IgG positive. She had a remote history of herpes simplex I infection 7 years previously. Once started on oral acyclovir, the lesions improved, and by day 15 postoperative, her pyrexia and all lesions completely resolved.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"st3\">\n<jats:title>Conclusion: <\/jats:title>\n<jats:p>HSV-1 should be suspected in patients with a previous history of HSV and postoperative pyrexia. Adequate prophylactic administration of acyclovir should result in resolution of these outbreaks, in this case, attributed to overly extensive spinal deformity surgery.<\/jats:p>\n<\/jats:sec>","DOI":"10.25259\/sni_1042_2021","type":"journal-article","created":{"date-parts":[[2021,11,16]],"date-time":"2021-11-16T10:28:34Z","timestamp":1637058514000},"page":"562","update-policy":"http:\/\/dx.doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Reactivation of herpes simplex labialis following adult spine deformity correction surgery"],"prefix":"10.25259","volume":"12","author":[{"given":"Nitin","family":"Adsul","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Idris","family":"Hamim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohan","family":"Banglore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2021,11,16]]},"reference":[{"key":"10.25259\/SNI_1042_2021\/ref-1","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1016\/S1386-6532(10)70002-0","article-title":"Advances in the understanding of the pathogenesis and epidemiology of herpes zoster","volume":"48","author":"Gershon","year":"2010","journal-title":"J Clin Virol"},{"key":"10.25259\/SNI_1042_2021\/ref-2","doi-asserted-by":"crossref","DOI":"10.1136\/jnnp.73.3.237","article-title":"Herpes simplex encephalitis","author":"Kennedy","year":"2002"},{"key":"10.25259\/SNI_1042_2021\/ref-3","doi-asserted-by":"crossref","first-page":"10980","DOI":"10.1073\/pnas.92.24.10980","article-title":"Reactivated and latent varicellazoster virus in human dorsal root ganglia","volume":"92","author":"Lungu","year":"1995","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.25259\/SNI_1042_2021\/ref-4","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1093\/infdis\/138.3.405","article-title":"Reactivation of herpes simplex virus after decompression of the trigeminal nerve root","volume":"138","author":"Pazin","year":"1978","journal-title":"J Infect Dis"},{"key":"10.25259\/SNI_1042_2021\/ref-5","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1097\/00003246-198408000-00003","article-title":"Herpes simplex virus reactivation in surgical patients","volume":"12","author":"Porteous","year":"1984","journal-title":"Crit Care Med"},{"key":"10.25259\/SNI_1042_2021\/ref-6","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1086\/340041","article-title":"Seroprevalence and coinfection with herpes simplex virus Type 1 and Type 2 in the United States, 1988-1994","volume":"185","author":"Xu","year":"2002","journal-title":"J Infect Dis"}],"container-title":["Surgical Neurology International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/surgicalneurologyint.com\/reactivation-of-herpes-simplex-labialis-following-adult-spine-deformity-correction-surgery\/","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/reactivation-of-herpes-simplex-labialis-following-adult-spine-deformity-correction-surgery\/","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,16]],"date-time":"2021-11-16T10:28:38Z","timestamp":1637058518000},"score":1,"resource":{"primary":{"URL":"http:\/\/surgicalneurologyint.com\/surgicalint-articles\/reactivation-of-herpes-simplex-labialis-following-adult-spine-deformity-correction-surgery\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,16]]},"references-count":6,"alternative-id":["10.25259\/SNI_1042_2021"],"URL":"https:\/\/doi.org\/10.25259\/sni_1042_2021","relation":{},"ISSN":["2152-7806"],"issn-type":[{"value":"2152-7806","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,16]]},"article-number":"562"}}